A5023375690- Barrier Structure and Function Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer-related molecular mechanisms research
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- GDF15 and Related Biomarkers
- TGF-β signaling in diseases
- Liver physiology and pathology
- Neurological Disease Mechanisms and Treatments
- Biochemical effects in animals
- Cholangiocarcinoma and Gallbladder Cancer Studies
Second Hospital of Anhui Medical University
2022
Anhui Medical University
2022
Bengbu Medical College
2018
Guang Fu Hospital
2014
The association between collagen type I alpha (COL1A) and chemoresistance has been verified in cancers. However, the specific role of COL1A2 gastric cancer (GC) cell resistance to apatinib, a highly selective small-molecule inhibitor vascular endothelial growth factor receptor 2, not investigated before. purpose this study was explore potential factors associated with regulation on GC apatinib vitro. With aid Oncomine database integrated bioinformatics methods, we identified overexpression...
Metastasis associated in colon cancer 1 (MACC1), a key regulator of the hepatocyte growth factor (HGF)/MET signaling pathway, has been implicated multiple human cancers. However, little is known regarding its expression and biological function gallbladder (GBC). In this study, we focused on clinical significance functions MACC1 GBC found that protein overexpression was frequently detected tissues. Patients with MACC1-positive tumors had worse overall survival than patients MACC1-negative...
Gallbladder cancer has a high recurrence and mortality rate, with limited treatment options. Therefore, elucidating the underlying molecular mechanisms of this disease would be beneficial to achieve an earlier diagnosis potentially identify novel targets. Claudin-1 is tight junction protein associated development prognosis several types cancer, our preliminary studies have demonstrated that claudin-1 expression elevated in gallbladder tissues. aim present study was investigate effects...