- Helicobacter pylori-related gastroenterology studies
- Galectins and Cancer Biology
- Veterinary medicine and infectious diseases
- Plant Stress Responses and Tolerance
- Postharvest Quality and Shelf Life Management
- Genetic Mapping and Diversity in Plants and Animals
- Genetic diversity and population structure
- Digital Marketing and Social Media
- Probiotics and Fermented Foods
- Microscopic Colitis
- Microbial Applications in Construction Materials
- Genetics, Aging, and Longevity in Model Organisms
- Animal Nutrition and Physiology
- Plant Molecular Biology Research
- Viral gastroenteritis research and epidemiology
- Evolution and Genetic Dynamics
- Diverse Aspects of Tourism Research
- IL-33, ST2, and ILC Pathways
- Immune Response and Inflammation
- Animal Disease Management and Epidemiology
- Agriculture, Soil, Plant Science
- Cancer-related molecular mechanisms research
- Sentiment Analysis and Opinion Mining
- Livestock and Poultry Management
- Eosinophilic Esophagitis
Capital Medical University
2018-2024
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Peking University Shougang Hospital
2023
Henan Institute of Science and Technology
2019
China Agricultural University
2005
Chinese Academy of Agricultural Sciences
2004
Biotechnology Research Institute
2004
State Key Laboratory of Plant Genomics
2004
Helicobacter pylori (H. pylori, Hp) has been designated a class I carcinogen and is closely associated with severe gastric diseases. During colonization in the mucosa, H. develops immune escape by inducing host tolerance. The epithelium acts as first line of defense against Toll-like receptors (TLRs) epithelial cells being sensitive to components subsequently activating innate system. However, mechanism tolerance induced through TLR signalling pathway not fully elucidated. In this research,...
Helicobacter pylori is designated as a class I carcinogen of human gastric cancer following long-term infection. During this process, H. bacteria persist in proliferation and death, release bacterial components that come into contact with epithelial cells regulate host cell function. However, the impact exposure to lysate on pathological changes not clear. In study, we aimed investigate regulation mechanisms involved dysfunction continuous lysate. We co-cultured lines GES-1 MKN-45 for 30...
Poultries including chickens, ducks, geese, and pigeons are widely used in the biological medical research many aspects. The genetic quality of experimental poultries directly affects results research. In this study, following electrophoresis analysis short tandem repeat (STR) scanning, we screened out microsatellite loci for determining characteristics Chinese pigeons. panels selected our provide a good choice monitoring population diversity native ducks.
ABSTRACT Helicobacter pylori is a microaerophilic Gram-negative bacterium that resides in the human stomach and classified as class I carcinogen for gastric cancer. Numerous studies have demonstrated H. infection plays role regulating function of host cells, thereby contributing to malignant transformation these cells. However, chronic process, short-term cellular experiments may not provide comprehensive understanding vivo situation, especially when considering lower oxygen levels stomach....
Identifying Helicobacter pylori (H. pylori, Hp) infection in animals before and after artificial influences the subsequent experiment. We established effective noninvasive detection methods, including gastric fluid nested polymerase chain reaction (PCR) method 13C-urea breath test, which can detect Hp modeling Mongolian gerbils. designed a gas collection equipment for PCR was also performed on fluid, mucosa, duodenal contents, faeces of gerbils challenged with Hp. Conventional rapid urease...