Han Li

ORCID: 0000-0003-4978-6502
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About
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Research Areas
  • Smart Agriculture and AI
  • Cancer-related molecular mechanisms research
  • Insect and Pesticide Research
  • MicroRNA in disease regulation
  • Plant Gene Expression Analysis
  • Remote Sensing in Agriculture
  • Plant biochemistry and biosynthesis
  • Plant Molecular Biology Research
  • RNA modifications and cancer
  • Insect and Arachnid Ecology and Behavior
  • Plant and animal studies
  • Plant Stress Responses and Tolerance
  • Plant-Microbe Interactions and Immunity
  • Plant tissue culture and regeneration
  • Insect-Plant Interactions and Control
  • Plant Genetic and Mutation Studies
  • Light effects on plants
  • Fungal Biology and Applications
  • Circular RNAs in diseases
  • Photosynthetic Processes and Mechanisms
  • Soil Carbon and Nitrogen Dynamics
  • Data Quality and Management
  • Leaf Properties and Growth Measurement
  • Phytochemicals and Antioxidant Activities
  • Legume Nitrogen Fixing Symbiosis

Anyang Hospital of Traditional Chinese Medicine
2025

Nanyang Institute of Technology
2025

Eye & ENT Hospital of Fudan University
2023-2025

Huazhong University of Science and Technology
2024-2025

Tongji Hospital
2024-2025

Ocean University of China
2014-2025

Kunming Medical University
2025

Hangzhou Medical College
2023-2024

Ministry of Agriculture and Rural Affairs
2022-2024

China Agricultural University
2018-2024

Entity matching (EM) has been a long-standing challenge in data management. Most current EM works focus only on developing algorithms. We argue that far more efforts should be devoted to building systems. discuss the limitations of systems, then present as solution Magellan, new kind Magellan is novel four important aspects. (1) It provides how-to guides tell users what do each scenario, step by step. (2) tools help these steps; seek cover entire pipeline, not just and blocking systems do....

10.14778/2994509.2994535 article EN Proceedings of the VLDB Endowment 2016-08-01

Background Platinum resistance is a major challenge in the clinical treatment of advanced ovarian cancer (OC). Accumulating evidence shows that tumor-promotive M2 macrophage linked to limiting chemotherapy efficacy multiple malignancies including OC. Circular RNAs (circRNAs) are novel class non-coding which function as critical regulator biological process cancer. However, their impact on polarization and chemoresistance OC remain unclear. Methods Platinum-resistant circRNAs were screened...

10.1136/jitc-2021-004029 article EN cc-by-nc Journal for ImmunoTherapy of Cancer 2022-03-01

WRKY transcription factors constitute a very large family of proteins in plants and participate modulating plant biological processes, such as growth, development stress responses. However, the exact roles are unclear, particularly non-model plants. In this study, Gossypium hirsutum WRKY41 (GhWRKY41) was isolated transformed into Nicotiana benthamiana. Our results showed that overexpression GhWRKY41 enhanced drought salt tolerance transgenic The exhibited lower malondialdehyde content higher...

10.1371/journal.pone.0143022 article EN cc-by PLoS ONE 2015-11-12

Abstract Mulberry fruits with high concentrations of anthocyanins are favored by consumers because their good taste, bright color, and nutritional value. However, neither the regulatory mechanism controlling flavonoid biosynthesis in mulberry nor molecular basis different fruit colors is fully understood. Here, we report that a homeostasis network comprising activation feedback regulation mechanisms determines color. In vitro vivo assays showed MYBA-bHLH3-TTG1 regulates anthocyanins, while...

10.1038/s41438-020-0302-8 article EN cc-by Horticulture Research 2020-05-31

In aging mice, osteoclast number increases in cortical bone but declines trabecular bone, suggesting that different mechanisms underlie age-associated loss these 2 compartments. Osteocytes produce the osteoclastogenic cytokine RANKL, encoded by Tnfsf11. Tnfsf11 mRNA of aged a mechanism underlying loss. To address this possibility, we mice lacking RANKL osteocytes. Whereas control lost between 8 and 24 months age, osteocytes gained during period. Mice both genotypes with age. Osteoclasts...

10.1172/jci.insight.138815 article EN cc-by JCI Insight 2020-09-01

The quaternization of compounds has emerged as a promising molecular design strategy for the development antibiotics. Herein, we report design, synthesis, antibacterial activities, and structure-activity relationships series novel pleuromutilin derivatives containing quaternary amine C-14 side chain. Most these exhibited broad-spectrum activity against tested bacteria. 10b was most effective agent that displayed excellent five clinical methicillin-resistant Staphylococcus aureus (MRSA)...

10.1021/acs.jmedchem.2c02135 article EN Journal of Medicinal Chemistry 2023-02-22

Leaf functional traits (LFTs) are highly plastic and essential to plant resource acquisition utilization. However, the collinearity of environmental factors differences in response distinct types generate challenges clarifying contributions environment variables LFTs. This study selected 28 species from four forests northern China with similar mean annual precipitation (MAP) explore how other dissimilar influence LFTs after controlling for most influential factor. Specifically, we examined...

10.1016/j.ecolind.2024.112199 article EN cc-by Ecological Indicators 2024-06-12

Tomato is well known fruit since it has many essential and beneficial nutrients like antioxidant, vitamin C A for human daily diet. picking by hand both labor time consuming. Therefore, to overcome these issues, tomato needs be picked up automatically with the help of harvesting robot. Recently automation gains great popularity. To guide robot pick correctly, important correctly detect find location red mature fruit. In this study, a new detection algorithm based on improved HSV (Hue,...

10.1016/j.ifacol.2018.08.183 article EN IFAC-PapersOnLine 2018-01-01

Abstract Cadmium (Cd) contamination in water and soil is considered an environmental pollutant. Food crops can absorb accumulate bioavailable Cd. Continuous monitoring of Cd levels the environment minimize exposure harm to humans. Visual pigments have been demonstrated great potential development minimal-equipment biosensors. In present study, a metabolically engineered bacterium was employed produce blue-purple pigment violacein responsive toxic Cd(II). The high stability bisindole...

10.1038/s41598-022-11051-9 article EN cc-by Scientific Reports 2022-04-27

Entity matching (EM) has been a long-standing challenge in data management. Most current EM works, however, focus only on developing algorithms. We argue that far more efforts should be devoted to building systems. discuss the limitations of systems, then present Magellan, new kind systems addresses these limitations. Magellan is novel four important aspects. (1) It provides how-to guide tells users what do each scenario, step by step. (2) tools help steps; seek cover entire pipeline, not...

10.14778/3007263.3007314 article EN Proceedings of the VLDB Endowment 2016-09-01
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