A5100416770- Arsenic contamination and mitigation
- Heavy Metal Exposure and Toxicity
- Acute Ischemic Stroke Management
- Cancer-related molecular mechanisms research
- Antibiotics Pharmacokinetics and Efficacy
- Geochemistry and Geologic Mapping
- Transplantation: Methods and Outcomes
- MicroRNA in disease regulation
- Geochemistry and Geochronology of Asian Mineral Deposits
- Aquaculture Nutrition and Growth
- Traumatic Brain Injury and Neurovascular Disturbances
- Geological and Geochemical Analysis
- Pharmaceutical and Antibiotic Environmental Impacts
- Autophagy in Disease and Therapy
- Liver Disease Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Liver Diseases and Immunity
- Respiratory Support and Mechanisms
- Pregnancy and preeclampsia studies
- Cerebrovascular and Carotid Artery Diseases
- Neurological Disease Mechanisms and Treatments
- Fish Biology and Ecology Studies
- Minerals Flotation and Separation Techniques
- Heavy metals in environment
- Glutathione Transferases and Polymorphisms
Guiyang Medical University
2016-2025
Wuxi People's Hospital
2017-2025
Nanjing Medical University
2017-2025
Soochow University
2011-2024
First Affiliated Hospital of Soochow University
2018-2024
Shanxi Medical University
2022-2024
Chinese Academy of Sciences
2008-2024
Affiliated Hospital of Guizhou Medical University
2019-2024
Guangxi Academy of Fishery Sciences
2019-2024
Ministry of Agriculture and Rural Affairs
2023-2024
Abstract Background Critical patients with the coronavirus disease 2019 (COVID-19), even those whose nucleic acid test results had turned negative and receiving maximal medical support, have been noted to progress irreversible fatal respiratory failure. Lung transplantation (LT) as sole therapy for end-stage pulmonary fibrosis related acute distress syndrome has considered ultimate rescue these patients. Methods From February 10 March 10, 2020, three male were urgently assessed listed...
The performance of thin film nanocomposite (TFN) membrane is significantly determined by the inherent structure and composition incorporated nanofillers. In this work, hydrophilic hollow nanocubes (HHNs) derived from zeolitic imidazolate framework 8 (ZIF-8) were into polyamide layer via an interfacial polymerization approach. HHNs with abundant hydroxyl groups on surface obtained etching solid ZIF-8 using tannic acid. Benefiting hydrophilicity, structure, negative charge HHNs, outstanding...
Previous studies reported that URB597 (URB) had therapeutic potential for treating chronic cerebral hypoperfusion (CCH)-induced neuroinflammation and autophagy dysfunction. However, the interaction mechanisms underlying CCH-induced abnormal excessive remain unknown. In this study, we investigated roles of impaired in nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing (NLRP) 3 inflammasome activation rat hippocampus under condition induced CCH as well...
Many Chinese jurisdictions are establishing "service-oriented" local governments in order to make public service delivery more effective and thereby increase government capacity. This article explores whether the use of e-government improves citizens' perceptions their government. The results indicate that accessing information through Web sites satisfaction with transparency. Citizens' frequent sites, partially mediated transparency, enhances capacity for delivery. Providing on indirectly...
Posttranslational modification of proteins could regulate their multiple biological functions. Transforming growth factor-β receptor I and II (ALK5 TGF-βRII), which are glycoproteins, play important roles in the renal tubular epithelial-mesenchymal transition (EMT). In present study, we examined role core fucosylation TGF-βRII ALK5, is regulated by α-1,6 fucosyltransferase (Fut8), process EMT cultured human proximal epithelial (HK-2) cells. The typical cell model induced TGF-β1 was...
Abstract URB597 (URB) has therapeutic potential for treating chronic cerebral hypoperfusion (CCH)-induced neuronal death. The present study investigated the protective effects of URB on autopahgy and mitophagy in a CCH model as well underlying mechanisms. ultrastructural changes were examined by electron microscopy. mitochondrial membrane was assessed immunofluorescence. expressions autophagy-related proteins (beclin-1, p62, LC3), lysosome-related (CTSD LAMP1), mitophagy-related (BNIP3, cyt...
Reactive oxygen species (ROS) induced by exogenous toxicants are suggested to be involved in carcinogenesis oxidative modification of DNA. 8-Hydroxyl-2-deoxyguanosine (8-OHdG) has been considered as a reliable biomarker for DNA damage both vivo and vitro studies. But the effect smoking on not yet fully elucidated.Wistar rats were exposed cigarette smoke at concentrations 20 60 % 30 min, twice/day 45 weeks. Then histopathology lung tissues, levels ROS, 8-OHdG, total antioxidant (T-AOC),...
Currently, most arsenic (As) studies in populations are concerned with water-borne arsenicosis. However, residents Xingren County of Guizhou Province, Southwest China, represent a unique case arsenicosis which is related to indoor combustion high As-containing coal. This study aimed assess the alterations As levels and its risk factors coal-borne during past 20 years. Four follow-up investigations were selected from year 1998 2017, total 245, 272, 584, 309 involved four investigations,...