A5000398115- Aquaculture disease management and microbiota
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Aquaculture Nutrition and Growth
- Invertebrate Immune Response Mechanisms
- Food Allergy and Anaphylaxis Research
- Viral Infectious Diseases and Gene Expression in Insects
- Animal Virus Infections Studies
- Allergic Rhinitis and Sensitization
- Animal Genetics and Reproduction
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Immunotherapy and Immune Responses
- Bacteriophages and microbial interactions
- Bat Biology and Ecology Studies
- Identification and Quantification in Food
- Turtle Biology and Conservation
- Immune responses and vaccinations
- Asthma and respiratory diseases
- Physiological and biochemical adaptations
- Protein purification and stability
- Blood groups and transfusion
- Advanced biosensing and bioanalysis techniques
- Reproductive biology and impacts on aquatic species
Universidade de Vigo
2003-2024
Galicia Sur Biomedical Foundation
2021
Virologie et Immunologie Moléculaires
2013-2019
University of New Mexico
2016-2019
Université Paris-Saclay
2016-2018
Instituto Español de Oceanografía
2009-2014
Institut National de la Recherche Agronomique
2013
Servicio Gallego de Salud
2013
Hospital Clínico San Carlos
2011
Instituto Superior de Saúde do Alto Ave
2008-2009
Inorganic nanoparticles (NPs) show great potential for medicinal therapy. However, biocompatibility studies are essential to determine if they safe. Here, five different NPs compared their cytotoxicity, internalization, aggregation in medium, and reactive oxygen species (ROS) production, using tumoral normal human blood cells. Differences depending on the cell type analyzed, no direct correlation between ROS production toxicity is found. Results discussed with aim of standardizing procedures...
With lymphoid tissue anatomy different than mammals, and diverse adaptations to all aquatic environments, fish constitute a fascinating group of vertebrate study the biology B cell repertoires in comparative perspective. Fish lymphocytes express immunoglobulin (Ig) on their surface secrete antigen-specific antibodies response immune challenges. Three antibody classes have been identified fish, namely IgM, IgD, IgT, while IgG, IgA, IgE are absent. IgM IgD found species analyzed, thus seem be...
Abstract Tetrapods contain a single CD4 coreceptor with four Ig domains that likely arose from primordial two-domain ancestor. Notably, teleost fish two genes. Like tetrapod CD4, CD4-1 of rainbow trout includes domains, whereas CD4-2 contains only two. Because is reminiscent the prototypic coreceptor, we hypothesized by characterizing cell types bearing and CD4-2, would shed light into evolution roles CD4-bearing cells. Using newly established mAbs against identified bona-fide CD4+ T...
Currently, there is still a need to improve the contiguity of rainbow trout reference genome and use multiple genetic backgrounds that will represent diversity this species. The Arlee doubled haploid line was originated from domesticated hatchery strain originally collected northern California coast. Canu pipeline used generate de-novo assembly high coverage PacBio long-reads sequence data. further improved with Bionano optical maps Hi-C proximity ligation data 32 major scaffolds...
Abstract Background Bony fish present an immunological system, which evolved independently from those of animals that migrated to land 400 million years ago. The publication whole genome sequences and the availability several cDNA libraries for medaka ( Oryzias latipes ) permitted us perform a thorough analysis immunoglobulin heavy chains in this teleost. Results We identified IgM IgD coding ESTs, mainly spleen, kidney gills using published but we did not find any sequence coded IgT or other...
<i>Background:</i> Lentils are increasingly consumed in many parts of the world.Two allergens, Len c 1 and 2, have been reported previously. Recently, peanut green bean lipid transfer proteins (LTPs) identified as first two members an important group allergens that might be associated with severe food allergies. <i>Objective: </i>To investigate lentil LTP a potential new allergen. <i>Methods:</i> Efficacy extraction was monitored at different acidic pH...
Bony fish represent the most basal vertebrate branch with a dedicated mucosal immune system, which comprises immunologically heterogeneous microenvironments armed innate and adaptive components. In rainbow trout (Oncorhynchus mykiss), nasopharynx-associated lymphoid tissue (NALT) was recently described as diffuse network of myeloid cells located in olfactory organ fish. Several studies have demonstrated high levels protection conferred by nasal vaccines against viral bacterial pathogens;...
In teleost fish as in mammals, humoral adaptive immunity is based on B lymphocytes expressing highly diverse immunoglobulins (IG). During cell differentiation, IG loci are subjected to genomic rearrangements of V, D, and J genes, producing a unique antigen receptor expressed the surface each lymphocyte. course an immune response infections or immunizations, clones specific epitopes from immunogen expanded activated, leading production antibodies. Among fish, salmonids comprise key species...
Vaccination induces "public" antibody clonotypes common to all individuals of a species, that may mediate universal protection against pathogens. Only few studies tried trace back the origin these public B-cell clones. Here we used Illumina sequencing and computational modeling unveil mechanisms shaping structure fish memory response an attenuated Viral Hemorrhagic Septicemia rhabdovirus. After vaccination, persistent with VH5JH5 IgM component was composed dominant antibodies shared among...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 316:115-125 (2006) - doi:10.3354/meps316115 Feeding strategies of copepod Acartia clausi on single and mixed diets toxic non-toxic strains dinoflagellate Alexandrium minutum A. Barreiro1,*, C. Guisande1, M. Frangópulos2, González-Fernández1, S. Muñoz1, D. Pérez1, Magadán1, I. Maneiro1, Riveiro1, P. Iglesias1...