Meng-Chuan Lu

ORCID: 0000-0003-2978-741X
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About
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Research Areas
  • Cancer, Lipids, and Metabolism
  • Cardiomyopathy and Myosin Studies
  • Reproductive biology and impacts on aquatic species
  • Meat and Animal Product Quality
  • Physiological and biochemical adaptations
  • Liver Disease Diagnosis and Treatment
  • Cancer Mechanisms and Therapy
  • Neurobiology and Insect Physiology Research
  • Muscle Physiology and Disorders
  • Abdominal vascular conditions and treatments
  • Acupuncture Treatment Research Studies
  • Ferroptosis and cancer prognosis
  • Hormonal Regulation and Hypertension
  • Infection Control in Healthcare
  • RNA Research and Splicing
  • Therapeutic Uses of Natural Elements
  • Retinopathy of Prematurity Studies
  • Hepatitis Viruses Studies and Epidemiology
  • Intramuscular injections and effects
  • Pharmacy and Medical Practices
  • Nitric Oxide and Endothelin Effects
  • Bacterial Genetics and Biotechnology
  • Complementary and Alternative Medicine Studies
  • Glaucoma and retinal disorders
  • Genetic Neurodegenerative Diseases

National Defense Medical Center
1982-2024

Tri-Service General Hospital
2001-2024

Cheng Ching Hospital
2015

Weatherford College
1998

University of Pennsylvania
1990

Cultured cardiac myocytes were stained with antibodies to sarcomeric alpha-actinin, troponin-I, alpha-actin, myosin heavy chain (MHC), titin, myomesin, C-protein, and vinculin. Attention was focused on the distribution of these proteins respect nonstriated myofibrils (NSMFs) striated (SMFs). In NSMFs, alpha-actinin is found as longitudinally aligned, irregular approximately 0.3-microns aggregates. Such aggregates are associated titin. These I-Z-I-like complexes also ectopic patches outside...

10.1083/jcb.110.4.1159 article EN The Journal of Cell Biology 1990-04-01

RNase J is a conserved ribonuclease that belongs to the β-CASP family of nucleases. It possesses both endo- and exo-ribonuclease activities, which play key role in pre-rRNA maturation mRNA decay. Here we report high-resolution crystal structures Deinococcus radiodurans complexed with RNA or uridine 5′-monophosphate presence manganese ions. Biochemical structural studies revealed uses zinc ions for two-metal-ion catalysis. One residue among orthologues (motif B) forms specific electrostatic...

10.1093/nar/gkv444 article EN cc-by-nc Nucleic Acids Research 2015-05-04

Lu, M; Kuroki, Amano, S; Tolentino, Keough, K; Kim, I; Bucala, R; Adamis, A P Author Information

10.1097/00006982-199805000-00030 article EN Retina 1998-05-01

Heart failure (HF) and cancer have similar risk factors. HMG-CoA reductase inhibitors, also known as statins, are chemoprotective agents against carcinogenesis. We aimed to evaluate the effects of statins liver in patients with HF. This cohort study enrolled HF aged ≥20 years between 1 January 2001 31 December 2012 from National Health Insurance Research Database Taiwan. Each patient was followed assess risk. A total 25,853 were for a 12-year period; 7364 used 18,489 did not. The decreased...

10.3390/cancers15112959 article EN Cancers 2023-05-29

Hepatocellular carcinoma accounts for approximately 90% of primary liver cancers and hepatitis virus was believed to have the potential altering pathogenesis arteriosclerosis. However, influence on coronary artery disease or cerebral vascular remains unclear. This study used Taiwan National Health Insurance Research Database clarify virus-associated risk in patients with hepatocellular (HCC). A total 188,039 HCC individuals, age 20 years older, were enrolled from Longitudinal between 2000...

10.3390/jcm12072602 article EN Journal of Clinical Medicine 2023-03-30

Background: Approximately 10–40% of hepatocellular carcinoma (HCC) patients have definite vascular invasion at the time diagnosis. Without curative treatment options, these an abysmal prognosis with a median survival only few months following systemic therapy. However, supportive evidence combining multiple locoregional treatments therapy is limited. This study compared outcomes sorafenib alone versus multimodality sorafenib, radiotherapy (RT), and transarterial chemoembolization (TACE) in...

10.3390/cancers15102687 article EN Cancers 2023-05-10

Upper gastrointestinal angiodysplasia (UGIA) is a unique mucosal vascular lesion that causes acute or recurrent bleeding. Despite the increasing incidence of UGIA, risk factors for bleeding in this condition remain unclear. We investigated predictors active and among patients with UGIA. conducted retrospective cohort study 104,086 who underwent esophagogastroduodenoscopy (EGD) at Tri-Service General Hospital Taiwan between October 2011 September 2021. UGIA was diagnosed 112 patients, data...

10.1097/md.0000000000040921 article EN cc-by-nc Medicine 2024-12-13

Ovaries of hypophysectomized Rana catesbeiana tadpoles. weighing I to 14 g, were prepared for electron microscopic study. The oocytes are at the growth phase, ranging from 50 190 μm in diameter. observation on these has revealed presence intramitochondrial yolk-crystals but not cytoplasmic yolk platelets. crystalline structure, situated within intracristal space, consists a hexagonal array dense particles about Å diameter and 72 periodicity. Our data agree with those reported intact ranid...

10.1111/j.1440-169x.1982.00319.x article EN Development Growth & Differentiation 1982-08-01

Introduction: Cupping therapy has been widely performed in oriental countries and considered a safety alternative to relieve pain. Here, we report rare complication from abdominal cupping. Case presentation: A 49-year-old man presented with 2-day history of left upper quadrant pain after cupping 3 days earlier. His abdomen was soft but appeared localized rebounding tenderness. Contrast-enhanced computed tomography the showed intraperitoneal hemorrhage originated omentum. Discussion: Several...

10.1177/1024907918784076 article EN cc-by-nc Hong Kong Journal of Emergency Medicine 2018-06-21

10.1016/j.jmii.2015.02.409 article EN publisher-specific-oa Journal of Microbiology Immunology and Infection 2015-03-28
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