Background: Myopia is a condition in which the visual images come to focus front of retina eye. This disease major cause disability, presents 108 million persons globally. Purpose: study aims determine relationship between degree myopia, axial length, and choroidal thickness (CT). Methods: an observational analytical that made use cross-sectional design. A total 59 participants with refractive errors underwent treatment at Hasanuddin University Hospital 116 eyes were measured analyzed. The...

INTRODUCTION: Diabetic retinopathy (DR) is the leading cause of blindness worldwide. Vitamin E (alpha-tocopherol) an essential micronutrient and a fat-soluble antioxidant with proposed role in delaying progression diabetic through its properties. Therefore, purpose this review was to examine alpha-tocopherol preventing retinopathy.EVIDENCE ACQUISITION: A literature search conducted using four online databases: PubMed, ScienceDirect, Google Scholar, Scopus. The terms included combinations...

Background The magnitude of blindness among children in Indonesia is unknown. In this study, we aimed to define the and aetiology childhood two parts Indonesia. Method Children aged 0–15 years, identified through key informant method from special schools community-based rehabilitation programme Sumba Yogyakarta, were assessed following WHO protocol definitions for ophthalmological assessment classification visual impairment children. Results Out 195 assessed, 113 had blindness/severe...

BACKGROUND: The genetic causes of congenital cataracts vary widely and are related to mutations in specific genes. Forkhead box protein E3 (FoxE3) is a transcription factor required the morphogenesis differentiation anterior segment eye. This study aims evaluate FoxE3 gene mRNA expression cataract patients.METHODS: was an analytic observational with cross-sectional design. sample comprised 14 patients 12 non-cataract control samples. Blood samples were taken, RT-PCR examined...

Abstract Background Diabetic retinopathy (DR) is the most common microvascular complication of diabetes. Retinol and α-tocopherol diabetic models prevent damage photoreceptor retinal ganglion cells (RGC) caused by hyperglycemia. Objective This study aims to examine effect retinol on RGC densities expression caspase-3 -7 layers rat model. Methods Alloxan 150 mg/kg body weight single dose was used develop animal models, which were separated into eight groups. These consist one group without...

Rhegmatogenous retinal detachment (RRD) is a serious and emergency condition that may cause visual disturbance. Treatment includes pars plana vitrectomy with tamponade such as intraocular gas or silicone oil (SO). In many countries, still favorable compared to gases for reattachment of surgery. The application provides higher anatomical success rate, especially in cases proliferative vitreoretinopathy (PVR) were previously considered untreatable. Objective assessment the nerve fiber layer...

This study aimed to investigate the concentrations of vascular endothelial growth factor (VEGF) and platelet-derived (PDGF) in vitreous serum samples, analyze ratio, compare among proliferative diabetic retinopathy (PDR) subgroups.This included 17 eyes patients with PDR, identified as PDR group which was divided into three subgroups (vitreous hemorrhage [VH], VH fibrotic tissues, tractional retinal detachment), five control (nucleus intraocular lens drop). Vitreous samples were obtained on...

Background: This study was aimed to compare the effect of laser photocoagulation (LF), intravitreal bevacizumab (IVB) and combined treatments on biomarkers oxidative stress such as aldehhyde dehidrogenase (ALDH), malondialdehyde (MDA) level, superoxide dismutase (SOD) activities, vitreal vascular endothelial growth factor (VEGF) proliferative diabetic retinopathy (DR) patients.Methods: In this single blind randomized clinical trial, 72 eyes from 69 cases DR in Cipto Mangunkusumo Hospital...

Background: Autoimmune diseases are systemic disorders that involve many organs, including the eyes, and play an important role in dry eyes. This review aims to elucidate relationship between eye disease (DED) autoimmune disease. Methods: literature utilized a database from 2020 until 2024. The keywords “dry disease”, “autoimmune

Introduction: Children eye health are one of the most common problems in ophthalmology that getting attention globally and nationally especially South Sulawesi. To optimize its services quality quantity human resources required. This study aims to report development children Sulawesi.
 Methods: Surveys were carried out several districts assess availability services. Creating collaborations with institutes such as Faculty Medicine, Hasanuddin University related professional...

Introduction: Diabetic retinopathy (DR) is the leading cause of blindness that rises significantly each year along with increasing diabetic population. It estimated 1 out 3 people diabetes will suffer from DR and in 10 them be threatened blindness. The main problem on management delay diagnosis since most patients early stages do not experience visual impairment.Methods: Descriptive research was conducted over three months 175 diagnosed type 2 Diabetes Mellitus (DM) within Internal Medicine...

Purpose : To compare the Ganglion Cell Complex (GCC) thickness with Retinal Nerve Fiber Layer(RNFL) in correlation visual field (VF) varying degrees of myopia. Design: a Cross-Sectional study. Participants: Ninety-six eyes 49 patients Methods: Patients withmyopia examined streak retinoscope to obtained best corrected acuity based onspherical equivalent. then divided into low (50 eyes=50.1%), moderate (31 eyes=32.3%), andhigh (15=15.6%) Axial length measured A-Scan ultrasound short...

Background: Interference is a condition of which sample components cause an error in the analyte measurement analyzer. The most common interference lipemic sample. Lipemic characterized by turbidity serum or plasma caused accumulation lipoprotein particles. Primary mixed hyperlipidemia (PMH) primary hypertrigliseridemia with lipemia manifestation.Case report: A three month-old baby boy was admitted to hospital, having white spots his black eyes. were seen clearer at light exposure, and...

BACKGROUND Retinoblastoma (RB) is an inherited disorder caused by the RB1 gene mutation in retinal cells or germline mutation. Identifying specific crucial for prognosis, inheritance risk assessment, and treatment planning. This study aimed to identify patients with RB their parents from eastern part of Indonesia.
 METHODS observational analytic recruited between 2016 2018 at Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia. The normal control subjects were children outpatient...

Pro-inflammatory cytokines are important contributors to dry eye disease (DED). The cytokine interleukin (IL)-6 has become a therapeutic target in several DED drug studies. This randomized controlled trial aimed determine the effectiveness of topical cyclosporin-A 0.1% compared combination and sodium hyaluronate reducing tear IL-6 levels patients.The participants were 20 patients, each with two eyes, who had moderate-to-severe DED. Before after treatment, clinical degree was examined group,...

Abstract
 Introduction & Objectives : Digital media is currently being increasingly used in recent years. The development of the visual system begins as soon a child born through stimulation and interaction with environment that develops comprehensively general children. Smartphone usage affects eye developmental process. Explain effect ocular biometry components refraction change elementary school children due to duration smartphone usage
 Methods A one-year cohort prospective...

Introduction & Objectives : Introduction: Retinopathy of Prematurity (ROP) is one the leading causes irreversible visual impairment in infants, especially premature infants. Preterm birth leads to incomplete development retina that will cause ROP. ROP screening an early strategy prevent blindness Objective: The purpose this study was describe characteristics Makassar between January 2020 and December 2022.
 Methods A multi-center observational descriptive at ten hospitals...

INTRODUCTION: In the diabetic retina, apoptosis is one of main processes that results in retinal cell death (RCD). The production caspase-3 may be utilized as an apoptotic marker for changes retina occur after developing diabetes. It important pathways and functions a signal severity tissue damage.EVIDENCE ACQUISITION: A literature review was performed on studies published from 2010 until 2023. key words "caspase-3," "apoptosis," "diabetic retinopathy," "oxidative stress," "antioxidants,"...

BACKGROUND: Congenital cataracts can cause visual impairment and blindness in infants, approximately 50% of all congenital cataract cases have a genetic basis. The most abundant membrane protein lens fiber cells is major intrinsic (MIP)/aquaporin 0 (AQP0), which facilitates the movement water into across acts as an adhesion molecule by forming "thin junctions." A that lacks AQP0 loses its regular shape has clear disorganization causing formation cataracts. This study aimed to assess mRNA...

The incidence of cancer is continually increasing with chemotherapy one the most common treatment modalities. use increasingly widespread for various types and can increase patient survival rates. Chemotherapy halts growth tumors by shutting down their ability to divide forcing apoptosis, however, its often has side effects. known produce cytotoxic effects on all eye compartments, including adnexa, anterior segment, posterior as well neuro-ophthalmic disorders. In Indonesia, studies ocular...

Link of Video Abstract: https://youtu.be/L9MLcss_SBI Introduction: Lacritin is a potential human tear glycoprotein for treating some diseases involving eye such as bacterial corneal ulcers. However, the specific role lacritin in improving condition still not known with certainty. The purpose this study to review diseases. Methods: This used literature from January 2001 until June 2023 according (Preferred Reporting Items Systematic Review and Meta-Analyses (PRISMA). was electronic databases;...