Abstract To determine the value of radiomics data extraction from baseline 18F FDG PET/CT in prediction tumor-infiltrating lymphocytes (TILs) among patients with primary breast cancer (BC). We retrospectively evaluated 74 who underwent scans for BC evaluation between October 2020 and April 2022. Radiomics resulted a total 131 radiomic features tumors. TILs status was defined based on histological analyses surgical specimens were categorized as having low or moderate & high TILs. The...

Abstract Background Cases with abnormal category, determined by thyroid fine‐needle aspiration (FNA), frequently undergo surgical resection, despite the majority of cases being identified as benign after resection. Additional diagnostic markers are needed to guide management patients nodules. Materials and Methods The retrospective study enrolled 150 diagnosed FNA cytology that had undergone molecular testing three (BRAF V600E, NRAS, KRAS) on cell block. Seventy‐one a follow‐up. Results When...

Mismatch repair (MMR)-deficient endometrial carcinomas show increased programmed cell death-ligand 1 (PD-L1) expression compared with MMR-intact carcinomas, but there are limited data regarding PD-L1 between sporadic and inherited exhibiting MMR loss. Most of the studies investigating in carcinoma have used tissue microarrays did not examine all tumor blocks. In this study, we analyzed resection specimens 176 consecutive using blocks; MMR-deficient including MLH1 PMS2-loss subgroup, other...

Our aim in this study is to define the histopathological subtypes, body site distribution, and incidence rates of single or multiple BCCs. The conducted on patients from a institution Istanbul which has migrant-receiving population reflecting that country overall.We retrospectively analyzed data concerning 896 cases BCC seen between 2014 2018. Data about patient demographics (age sex), tumor diameter,its anatomic localization, histological type, presence ulceration, lymphovascular/perineural...

Oligosarcoma is a recently identified entity characterized by sarcomatous changes originating from oligodendroglioma. As of our current understanding, components are infrequent in glial tumors. The World Health Organization (WHO) classification describes features as rare pattern grade 3 oligodendrogliomas. In this report, we present 42-year-old man diagnosed with oligosarcoma. patient initially presented lesion the right parietotemporal area 9 years ago, and pathological diagnosis was Nine...

Angiotropism/perivascular invasion (PVI) is an emerging topic in various types of cancer, with studies primarily focusing on melanoma. However, limited data are available the significance PVI breast cancer. This study aimed to assess prognostic cancer and its correlation traditional clinicopathological parameters. A total 150 patients diagnosed between July 2020 January 2022 were included. Clinicopathological retrieved from hospital records. The presence was evaluated hematoxylin&eosin...

Background and Objectives: Among breast cancer molecular types, HER2 positive triple negative (TN) subtypes have the highest likelihood of pathological complete response (pCR), which is a surrogate marker for reduced recurrence improved patient survival after neoadjuvant systemic treatment (NST). Preoperative identification these exceptional responders new era. Therefore, we aimed to determine accuracy trucut biopsy in identifying selected patients. Materials Methods: This two-centre,...

Inflammatory myofibroblastic tumors (IMTs) of the breast are extremely uncommon lesions, usually labelled as a subgroup inflammatory pseudotumors. They composed cells and bland spindle without nuclear atypia. Nearly half all IMTs include clonal translocation anaplastic lymphoma kinase (ALK) gene, located at chromosome band 2p23, generally present with palpable lump, swelling, pain. Herein, we 66-year-old female patient pain, swelling lump in her right breast. A 40×26 mm sized T1A hypointense...

The aim of this study was to evaluate the correlation between clinical histopathologic features and micropapillary (MP) ratio with maximum standardized uptake value (SUVmax) derived from 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in treatment naïve breast cancer.Twenty-nine patients diagnosed cancer a MP component who underwent PET/CT imaging before any local and/or systemic were included retrospective study. All histopathological recorded....

What is known on this subject?Image-guided breast biopsy commonly used for diagnosis of lesions.Breast ultrasound (US), which also screening purposes, an important tool guiding biopsies. study adds?Our findings demonstrate a high radiologichistopathologic correlation rate in US-guided samples.We observed the highest discordance Breast Imaging Reporting and Data System (BI-RADS) 4 lesions.Therefore, histopathological verification necessary patients with BI-RADS lesions to exclude malignancy.

The most common type of renal cancers is the clear cell carcinoma (CCRCC) and 98% CCRCCs have a loss sequence in short arm chromosome 3 by deletion or translocation. Programmed death; another possible mechanism tumorigenesis, comprises two separate components: apoptosis autophagy. This study aims to show rela-tion between prognostic parameters survival, Beclin-1, as representative marker autophagy, Bcl-2 CCRCC patients. In this study, we aimed determine if Beclin-1 expression levels can...

Today breast cancer is the most common type in women, both developed and developing countries. However, occult a highly rare all cancers. For first time history to know, Halsted defined term “occult cancer” with 2 cases of his’ journal, Annals Surgery. We have similar who were 52 61-years-old patients presented our clinic left axillary swelling pain. On physical examination imaging techniques there wasn’t any primary lesion found. Examination lymph nodes’ biopsy material was compatible...

Leiomyomatosis peritonealis disseminata in a nonpregnant woman

Amaç: Merkel hücreli karsinom nadir görülen

There are limited data regarding the correlation of clinical and pathologic parameters with mismatch repair (MMR) protein-deficient subgroups methylation status. In this study, we analyzed status MMR proteins in resection specimens 198 consecutive endometrial carcinomas tumors MLH1 PMS2 deficiency. We, therefore, assessed subgroups. Univariate analysis revealed that deeper myometrial invasion presence tumor-associated lymphocytes were more frequently observed protein deficiency ( P =0.023...

Abstract Gangliogliomas are rare mixed neuronal-glial tumors of the central nervous system. They constitute less than 2% intracranial neoplasms. slow-growing, well-differentiated, and partly calcified tumors. Sellar-suprasellar gangliogliomas very [1]. Although many studies have included only cerebral hemisphere gangliogliomas, tumor could not be classified according to its location because small number patients in most [2]. Herein, a case pediatric ganglioglioma sellar parasellar region is...

Pathology plays a major role in the management of patients. Specimen delivery to pathology laboratory is first step process. Sending materials should be included as part residency training. The aim this study was determine level knowledge and daily practice residents who send laboratory.

<title>Abstract</title> Background Cerebral vasospasm following endoscopic transsphenoidal surgery is rare. In this study, we present a case of sellar-suprasellar pilocytic astrocytoma with the rare and serious complication cerebral after surgery, who had plasminogen activator inhibitor type-1 4G/4G genotype. Case description A 7-year-old female patient presented complaints headache nausea. Upon detection lesion in region, initial intervention involved tumor excision placement an...