A5043548048- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Leptospirosis research and findings
- Toxoplasma gondii Research Studies
- Insect and Pesticide Research
- Vector-Borne Animal Diseases
- Zoonotic diseases and public health
- Cytomegalovirus and herpesvirus research
- Vector-borne infectious diseases
- Parasites and Host Interactions
- Viral Infections and Vectors
- T-cell and Retrovirus Studies
- Dermatological diseases and infestations
- Forensic Entomology and Diptera Studies
- Immunodeficiency and Autoimmune Disorders
- Maternal and Neonatal Healthcare
- Insect symbiosis and bacterial influences
- Parasite Biology and Host Interactions
- History of Medicine and Tropical Health
- Science and Education Research
- Entrepreneurship Studies and Influences
- Parvovirus B19 Infection Studies
- Race, Identity, and Education in Brazil
- Bartonella species infections research
- Insects and Parasite Interactions
Instituto Adolfo Lutz
2015-2024
Instituto de Saúde
2020
Universidade de São Paulo
2020
Universidade Estadual Paulista (Unesp)
2020
Escola Nacional de Saúde Pública
2006
Secretaria da Saúde
1992
In October, 1986, 7 to 22 days after a meeting at farm in Paraíba state, 26 individuals presented with febrile illness associated bilateral eyelid and lower limb edema, mild hepatosplenomegaly, lymphadenopathy and, occasionally skin rash. A 11-year-old boy exhibited atrial premature complexes 74-year-old patient developed acute heart failure. two patients hospitalized São Paulo city, Chagas' disease was diagnosed by the demonstration of circulating Trypanosoma cruzi. At autopsy fatal case,...
Estimate the coverage of control measures visceral leishmaniasis and relate them with occurrence human in endemic urban area.Cases canine were considered as study population evaluated by a serological survey conducted Araçatuba, state São Paulo, from 2007 to 2015. The cases geocoded address patients disease dogs' owners. survey, euthanasia, insecticide spraying was calculated, well seroprevalence incidence rates leishmaniasis. relationship between evaluated, comparing maps linear regression....
Immune reconstitution inflammatory syndromes (IRISs) have been reported in patients with human immunodeficiency virus/acquired syndrome (AIDS) since the introduction of highly active antiretroviral therapy (HAART). This is characterized by clinical manifestations opportunistic infections when signs immune are observed during therapy. We report on leishmaniasis, suggestive HAART-induced IRIS, 2 AIDS. After beginning HAART, 1 patient presented disseminated, tegumentary lesions, whereas other...
To evaluate the possible role of parasitemia on Chagas' disease reactivation in disease/human immunodeficiency virus (HIV) coinfection cases and impact HIV Trypanosoma cruzi genetic diversity, 71 patients with (34 HIV+ 37 HIV-) were surveyed. Moreover, 92 T. stocks from 47 chronic chagasic (29 18 isolated analyzed by multilocus enzyme electrophoresis a random amplified polymorphic DNA procedure. High appeared to play major reactivation. In patients, diversity population structure (clonality)...
Relata-se o quadro clínico de 27 pacientes com doença Chagas aguda, acompanhados no ambulatório da Clínica Doenças Infecciosas e Parasitárias do Hospital das Clínicas FM-USP período 1974 a 1987. As vias transmissão envolvidas foram: vetorial em 7 casos, transfusional 9, transplante rim e/ou 4, acidental 1, via oral 3, provável aleitamento materno congênita ou 1. Pacientes infecção por eram procedentes Bahia Minas Gerais, tendo 6 apresentado 1980 um Já os infectados adquiriram na Grande São...
Toxoplasmosis is a highly prevalent zoonotic human infection caused by the Apicomplexa protozoon Toxoplasma gondii. The acute disease usually mild or asymptomatic, except for foetal transmitted acutely infected pregnant women, which courses as devastating disease. In order to determine possible regional variations in risk factors, we studied frequency of seronegativity areas São Paulo Metropolitan Region, comparing titers and age groups. prevalence was determined retrospectively 1286 women...
When it comes to visceral leishmaniasis (VL) in Brazil, one of the main targets public health policies surveillance is control domestic canine reservoirs Leishmania infantum. This paper aims evaluate effect dog population and household environment for maintenance natural foci transmission human animal hosts an endemic city VL, Bauru, Brazil. We collected 6,578 blood samples dogs living 3,916 households from Nov.2019 Mar.2020 applied geospatial models predict disease risk based on population....
Flebotomíneos são insetos de importância médica, responsáveis pela transmissão parasitas do gênero Leishmania entre humanos e animais não humanos, os quais encontrados no estado São Paulo, Brasil. A correta identificação das espécies envolvidas na doenças é fundamental para elaboração estratégias o controle desses vetores. Para produzir uma chave ilustrada as 67 machos 57 fêmeas flebotomíneos registradas examinamos ilustramos espécimes montados em lâminas microscopia obtidos coleções entomológicas.
Background Leishmaniasis is a rapidly expanding zoonosis that shows increasing urbanization. Concern exists regarding the role of wildlife in visceral leishmaniasis (VL) transmission, due to frequent natural or anthropogenic environmental changes facilitate contact between wildlife, humans and their pets. The municipality Campinas, southeastern Brazil, initially recorded VL 2009, when first autochthonous case was confirmed dog living an upscale residential condominium, located inside...
Other authors have demonstrated that itraconazole has antiparasitic activity against Trypanosoma cruzi both in vitro and animal acute infection. Because of these observations, we decided to evaluate the chronic phase this protozoal disease, since it is most important form under a clinical assistential point view. We studied an infected mouse model as well human cases Chagas' disease. One hundred mg/kg/day by gastric tube, 100 or 200 mg/day orally were given, respectively, during three...
In the last decade, in state of São Paulo, 5898 cases cutaneous leishmaniasis (CL) were reported. This study was undertaken to analyze epidemiology CL municipality Teodoro Sampaio, Paulo State, Brazil, based on a geographic approach, as very little is known relationship between and spatial transformation process.This population-based quantitative, descriptive cross-sectional case study. Surveys official notifications healthcare center sources from 1998 2011 analysed. The data described...
The incidence of visceral leishmaniasis (VL), one the most important neglected diseases worldwide, is increasing in Brazil. objectives this study were to determine canine VL (CanL) seroprevalence an urban area Araçatuba municipality and evaluate its relationship with characteristics dogs their owners.The CanL was 0.081 (95% credible interval [CI]: 0.068-0.096). following covariates/categories positively associated occurrence a seropositive dog: more than 10 that had lived house (odds ratio...
BACKGROUND Dogs are the main peridomiciliary reservoir of Leishmania infantum thus correct diagnosis infection is essential for control transmission and treatment as well. However, based on serological assays that not fully effective. OBJECTIVE We aimed to establish an effective assay L. infected dogs using Leishmania-derived recombinant antigens. METHODS derived rK39-, rK28-, rKR95-based enzyme-linked immunosorbent (ELISA) was standardized symptomatic asymptomatic infantum-infected dogs....
Leishmaniasis is a public health problem worldwide. We aimed to predict ecological niche models (ENMs) for visceral (VL) and cutaneous (CL) leishmaniasis the sand flies involved in transmission of São Paulo, Brazil. Phlebotomine were collected between 1985 2015. ENMs created each fly species using Maximum Entropy Species Distribution Modeling software, 20 climatic variables determined. Nyssomyia intermedia (Lutz & Neiva, 1912) Lutzomyia longipalpis 1912), primary vectors CL VL, displayed...
Leishmaniasis is a vector-borne parasitic protozoan infection that affects mammals and involves complex epidemiology. Although dogs are considered the main reservoir in zoonotic visceral leishmaniasis (VL), possible presence of other mammalian species acting as reservoirs has been associated cause lack success control human VL many endemic areas. The knowledge about natural infections some still scarce, such nonhuman primates (NHP), especially from genus Callithrix (marmosets). We...
Determination of the rate Trypanosoma cruzi infection in its triatomine vectors is an element control programmes directed at reducing transmission organism to humans. Traditionally, T. has been detected these insects by microscopical examination intestinal contents or excreta. The sensitivity this laborious process not defined because lack a bench-mark method against which could be compared. purpose study was compare polymerase chain reaction (PCR) assay with that for detecting Triatoma...
There is a growing concern about the participation of wild hosts and reservoirs in epidemiology leishmaniasis, particularly within context increasingly frequent environmental changes expansion One Health concept. This work molecular research infection by Leishmania spp. among wildlife an environmentally protected area located municipality Campinas, São Paulo, Brazil. The studied has history intense changes, with notifications human cases cutaneous leishmaniasis 1990s, focus canine visceral...