- Research on Leishmaniasis Studies
- Fungal Infections and Studies
- Toxoplasma gondii Research Studies
- Leptospirosis research and findings
- Viral Infections and Vectors
- Parasitic Infections and Diagnostics
- Trypanosoma species research and implications
- Vector-borne infectious diseases
- Herpesvirus Infections and Treatments
- Plant Pathogens and Fungal Diseases
- Milk Quality and Mastitis in Dairy Cows
- Antifungal resistance and susceptibility
- Infectious Diseases and Mycology
- Microbial infections and disease research
- Probiotics and Fermented Foods
- Mosquito-borne diseases and control
- Zoonotic diseases and public health
- Poxvirus research and outbreaks
- Veterinary medicine and infectious diseases
- Rabies epidemiology and control
- Nail Diseases and Treatments
- Pharmaceutical and Antibiotic Environmental Impacts
- Tuberculosis Research and Epidemiology
- Bacterial biofilms and quorum sensing
- Enterobacteriaceae and Cronobacter Research
Universidade Estadual Paulista (Unesp)
2010-2025
Instituto Adolfo Lutz
2016-2025
The development of new approaches allowing for the early assessment COVID-19 cases that are likely to become critical and discovery therapeutic targets urgently required. In this prospective cohort study, we performed proteomic laboratory profiling plasma from 163 patients admitted Bauru State Hospital (Brazil) between 4 May 2020 July 2020. Plasma samples were collected upon admission routine analyses shotgun quantitative label-free proteomics. Based on course disease, divided into three...
Abstract Background Paracoccidioides brasiliensis ecology is not completely understood, although several pieces of evidence point to the soil as its most probable habitat. The present study aimed investigate fungal growth, conidia production and molecular pathogen detection in different conditions. Methods Soils samples clayey, sandy medium textures were collected from ground surface interior armadillo burrows a hyperendemic area Paracoccidioidomycosis. P . was inoculated with controlled...
Paracoccidioides brasiliensis infections have been little studied in wild and/or domestic animals, which may represent an important indicator of the presence pathogen nature. Road-killed animals used for surveillance vectors zoonotic pathogens and offer new opportunities eco-epidemiological studies paracoccidiodomycosis (PCM). The P. infection was evaluated by Nested-PCR tissue samples collected from 19 road-killed animals; 3 Cavia aperea (guinea pig), 5 Cerdocyon thous (crab-eating-fox), 1...
Q fever and brucellosis are zoonoses that cause other systemic clinical signs in humans; their occurrences neglected the differential diagnosis for some diseases is disregarded. This study aimed to investigate seropositivity Coxiella burnetii Brucella spp. antibodies patients suspected of dengue from 38 municipalities state São Paulo, Brazil. The samples (n = 604) were obtained by convenience Adolfo Lutz Institute serum bank. Sera subjected an indirect immunofluorescence assay (IFA) using...
Synanthropic rodents, mainly rats and mice, become ecologically associated with men due to changes in their ecosystems caused by human activities. These animals may take part the epidemiological cycles of several diseases, including toxoplasmosis. The presence serum antibodies Toxoplasma gondii 43 rodents captured urban area Umuarama, PR, Brazil, was verified modified agglutination test (MAT). Brain heart samples were also collected bioassayed mice for isolation parasite. Isolated analyzed...
The performance of a commercial immunofluorescence assay (IFA commercial), an in-house in-house) and indirect enzyme-linked immunosorbent (ELISA) were evaluated in the detection antibodies anti-C. burnetii serum Q fever patients persons without disease. For study, seropositive seronegative samples for (n = 200) from bank Instituto Adolfo Lutz Brazil used. Commercial IFA was considered this study as gold standard diagnosing fever. demonstrated good agreement with test, showing high...
Listeriosis is a zoonosis whose etiological agent the bacterium Listeria monocytogenes. Milk and dairy products are considered excellent substrates for development of L. Using conventional PCR, monocytogenes was investigated in 102 samples raw milk from bulk tanks small farms. Also, microbiological analysis performed positive by PCR. The primers such as PRS, LM1/LM2, inlA, inlC, inlJ were used spatial analysis. PRS indicated positivity 20.58%, inlC 21.57%. inlA LM1/LM2 negative. Our findings...
INTRODUCTION: Toxoplasma gondii and Neospora caninum are related Apicomplexa parasites responsible for systemic diseases in many species of animals, including dogs. METHODS: This study aimed to determine the occurrence T. N. infections 50 dogs with neurological signs that were admitted Veterinary Hospital Universidade Estadual Paulista, City Botucatu, Brazil. All animals screened antibodies using an immunofluorescent antibody test both parasites. Tissues positive bioassayed mice (T. gondii)...
Detection of Leptospira by PCR had not yet been described in snakes. This study investigated, microscopic agglutination test (MAT) and PCR, the presence antibodies to spp. spp., respectively, venomous non-venomous wildlife captivity All snakes were divided into three groups be compared: Group 1 (wildlife - WS); 2 (snakes intensive IC), 3 (collective semi-extensive -CC). Of 147 studied, 52 (35.4%) positive for leptospirosis MAT, 8 (15.4%) belonging (WS), 34 (65.4%) (IC) 10 (19.2%) (CC)....
ABSTRACT: Hemoparasitic infections are tick-borne diseases, which affect animals and humans. Considering the importance of canine hemoparasitic in veterinary clinics, this study aimed to determine occurrence Anaplasma platys, Ehrlichia canis Babesia vogeli blood samples from 182 dogs not domiciled city Pato Branco, southwestern region Paraná State, Brazil, using polymerase chain reaction (PCR). The prevalence A. platys B. was 32.9% 10.9% respectively, infection prevailed (p<0.001). number...
Road-killed wild animals have been classified as sentinels for detecting such zoonotic pathogens Leishmania spp., offering new opportunities epidemiological studies of this infection.This study aimed to evaluate the presence spp. and chagasi DNA by PCR in tissue samples (lung, liver, spleen, kidney, heart, mesenteric lymph node adrenal gland) from 70 road-killed animals.DNA was detected tissues one Cavia aperea (Brazilian guinea pig), five Cerdocyon thous (crab-eating fox), Dasypus...
This work describes natural infection by Leishmania in a domestic cat where amastigote forms of the parasite were observed popliteal lymph node imprint. Positive and negative serological reactions enzyme-linked immunosorbent assay (ELISA) indirect immunofluorescence (IFA), respectively. Polymerase chain reaction (PCR) revealed that nucleotide sequence sample was identical to (L.) chagasi. is first report disease felines city Andradina, SP, an area considered endemic for canine human visceral...
INTRODUCTION: White piedra is a superficial mycosis caused by the genus Trichosporon and characterized nodules on hair shaft. METHODS: The authors report family referred to as pediculosis. Mycological culture Mycosel® plus molecular identification was performed precisely identify etiology. RESULTS: A spp. infection revealed. procedure identified agent inkin. CONCLUSIONS: T. inkin are rarely reported in Southern Brazil. tools essentials identifying species.
Abstract Water is indispensable for life and its quality directly related to public health. The objective of this study was investigate the presence Pseudomonas aeruginosa in water supply municipalities São Paulo State, Brazil. Analyses were carried out at Adolfo Lutz Institute between February December 2016, included physicochemical (chlorine, pH, color, turbidity nitrate), microbiological parameters (total coliforms Escherichia coli), as well P. aeruginosa, with susceptibility tests...
When it comes to visceral leishmaniasis (VL) in Brazil, one of the main targets public health policies surveillance is control domestic canine reservoirs Leishmania infantum. This paper aims evaluate effect dog population and household environment for maintenance natural foci transmission human animal hosts an endemic city VL, Bauru, Brazil. We collected 6,578 blood samples dogs living 3,916 households from Nov.2019 Mar.2020 applied geospatial models predict disease risk based on population....