A5104706233- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Pluripotent Stem Cells Research
- Ovarian function and disorders
- Reproductive Physiology in Livestock
- Prenatal Screening and Diagnostics
- Animal Genetics and Reproduction
- Statistical Methods in Clinical Trials
- Human Health and Disease
- Toxoplasma gondii Research Studies
- Renal and related cancers
- Health Systems, Economic Evaluations, Quality of Life
- Glycosylation and Glycoproteins Research
- Economic and Financial Impacts of Cancer
IVI Murcia Clinic
2009-2022
Hospital Reina Sofía de Murcia
2018
Universidad de Murcia
2004-2006
Is there an association between blastocyst collapse patterns and implantation potential? Embryos that exhibit are as likely to hatch those do not, but less implant should not be replaced if alternatives available. Studies of in different species mammals have found most blastocysts, experience consecutive weak contractions, successfully whereas strong contractions or collapse, fail hatch. Retrospective cohort study. Seven hundred fifteen transferred blastocysts were analyzed from July 2012...
Abstract Sperm binding activity has been detected in zona pellucida (ZP) glycoproteins and it is generally accepted that this resides the carbohydrate moieties. In present study we aim to identify some of specific molecules involved bovine sperm–ZP interaction. We performed sperm competition assays, vitro fecundation (IVF) combination with different lectins, antibodies neuraminidase digestion, chemical cytochemical analysis ZP. Both MAA lectin recognising α‐2,3‐linked sialic acid from...
Abstract STUDY QUESTION Does culture in a high relative humidity atmosphere improve clinical outcomes when using time-lapse integrated incubator and single-step medium? SUMMARY ANSWER Using an system medium, increases the likelihood of embryos, especially those subjected to preimplantation genetic testing for aneuploidies, achieve pregnancy compared cultured dry conditions. WHAT IS KNOWN ALREADY The use humid inside incubators can reduce changes media osmolality, which has been reported have...
Carbohydrates play a key role in different reproductive events, such as the sperm–oviductal cell interaction and sperm–oocyte recognition. For example, β-d-galactose α-d-mannose residues contained zona pellucida have been identified sperm receptors porcine oocytes (Song et al. 1999 J. Mamm. Ova Res. 16). The glycosidases, enzymes that remove carbohydrates, could an important tract, modulating decisive physiological events mediated by carbohydrates. However, enzymatic activity level of these...
Carbohydrates play a key role in different reproductive events such as the sperm–oviductal cell interaction and sperm–oocyte recognition. In this way, α-d-mannosyl (Amari et al. 2006 Mol. Reprod. Dev. 59, 221–226) α-2,3-sialic acid (Velasquez press) residues contained zona pellucida have been identified sperm receptors bovine oocytes. The glycosidases, enzymes that remove carbohydrates, could an important tract, modulating decisive physiological mediated by carbohydrates. However, enzymatic...
ABSTRAC : perm-egg interaction is a complex process mediated by receptors and ligands present in both gametes, spermatozoon and oocyte. The important role played the carbohydrates gamete interaction well documented. However, identification of molecules involved this remains unsolved. A carbohydrate modification sialic acid contents bovine zona pellucida (ZP) post fertilization has been previously reported. no evidence exists on implication sperm-ZP interaction. In study, we investigate...
Abstract Study question Does culture in high relative humidity conditions (HC) improve pregnancy rates when using a time-lapse system (TLS) and single-step (SS) medium? Summary answer Using an integrated-TLS SS medium, under HC increases the likelihood of embryos to achieve with respect those cultured DC. What is known already Many variables affect embryo development, need be precisely tuned every IVF laboratory, especially inside incubators. TLS provide stability during culture, which...