A5004869107- Neurofibromatosis and Schwannoma Cases
- Pancreatic and Hepatic Oncology Research
- Sarcoma Diagnosis and Treatment
- Nonmelanoma Skin Cancer Studies
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Ear and Head Tumors
- Health Systems, Economic Evaluations, Quality of Life
- Economic and Financial Impacts of Cancer
- Cancer and Skin Lesions
- Neuroblastoma Research and Treatments
- Lung Cancer Treatments and Mutations
University of Arizona
2018-2022
University of Arizona Cancer Center
2018-2019
Malignant peripheral nerve sheath tumors (MPNSTs) represent a rare subtype of neural crest cell-derived soft tissue sarcomas (STS). Standard care therapy comprises surgical resection followed by adjuvant radiation, and most clinical studies have demonstrated finite survival benefit radiation chemotherapy. In metastatic disease, palliative chemotherapy provides very limited efficacy. We report 60-year-old male patient with primary para vertebral tumor at T7-T8 lung metastases who recurred...
The low prevalence rate and limited literature on eccrine carcinoma (EC) pose a challenge to properly diagnosing treating this rare malignancy. EC lesions tend present similarly other cutaneous neoplasms dermatitis-like conditions. Efficacious treatment guidelines have not been established for patients diagnosed with EC, few regimens demonstrated clinical benefit. Due the high metastatic potential of recognizing presentation, diagnosing, utilizing beneficial options are important managing...
Matched-targeted and immune checkpoint therapies have improved survival in cancer patients, but tumor heterogeneity contributes to drug resistance. Our study categorized gene mutations from next generation sequencing (NGS) into three core processes. This annotation helps decipher complex biologic interactions guide therapy. We collected NGS data on 145 patients who failed standard therapy (2016 2018). One hundred forty two had for tissue (Caris MI/X) plasma cell-free circulating DNA...