Objective To evaluate the performance of a novel immunochromatographic card test (TRURAPID® O.K.N.V.I. RESIST-5) for rapid detection five carbapenemase enzymes in metallo-beta-lactamase (MBL) producing organisms, compared to real-time PCR and an advanced expert system. Methods Isolated clinically 100 non-duplicates multidrug-resistant Gram-negative bacilli (GNB) expressing MBL production were tested using IC card, PCR, Vitek-2 Advanced Expert System (AES). Sensitivity, specificity,...

A 5-year-old male, drowsy, jaundiced child presented with fulminant hepatitis and had HAV HEV infection. He hepatic encephalopathy grade 1, fever, pallor, hypotension, crepitations in his right lung base hepatosplenomegaly dyspnoea. highly raised liver enzymes hypoalbuminemia (2.8 g/dl) but anemia (hemoglobin of 7.7 g/dl 5.7 2 days later), reticulocytopenia severe thrombocytopenia (44 × 109/l) were unexplained. Parvovirus B19-specific IgM antibodies B19 DNA found the serum child. Chest X-ray...

Introduction Urinary tract infections (UTIs) are one of the most common bacterial encountered in community and healthcare settings. Increasing antimicrobial resistance patterns worldwide have limited treatment options available. Overuse carbapenems which were considered as last resort for multi-drug resistant UTIs over past decade has led to emergence carbapenem-resistant Enterobacterales (CRE). Ceftazidime-avibactam is a novel beta-lactam inhibitor combination drug indicated complicated...

There are few reports of "microfilaria in the urine." We report an elderly woman with gross hematuria who was being investigated for urinary tract tuberculosis. Three consecutive urine samples showed microfilaria Wuchereria bancrofti. However, she did not have chyluria. Treatment diethylcarbamazine cleared up within 3 days. Chyluria, hematuria, and hematochyluria problems Bancroftian filariasis reported worldwide. The literature review made to present a simplified way management.

Introduction Dermatophytosis is a common infection of the skin, hair, and nails caused by dermatophytes, group filamentous fungi capable digesting obtaining nutrients from keratin. Dermatophytes comprise three important genera: Epidermophyton, Microsporum, Trichophyton. This study aimed to analyze antifungal susceptibility patterns Trichophyton mentagrophytes isolates using epsilometer test (E-test) method. Material methods prospective observational was conducted on clinically suspected...

Background: Healthcare-associated diarrhea (HCAD) is that develops at least after 3 days of hospitalization, with the most common infectious cause being Clostridioides difficile.Over last decade, there has been a remarkable growth in frequency and severity C. difficile infection (CDI), making it one prevalent healthcare-associated infections.This study aimed to analyze prevalence risk factors associated CDI. Materials methods: A total 107 patients clinical suspicion having HCAD were included...

Abstract Aspergillus spp . are fungi which mostly nonpathogenic, but some species such as fumigatus , flavus and niger can cause aspergillosis in humans. Aspergillosis manifest pulmonary or extrapulmonary infections, with respiratory involvement being common infections other body parts rare. Urinary aspergillosis, an uncommon manifestation of infection, presents unique challenges diagnosis management due to its rarity varied clinical presentations. It is seen immunocompromised individuals,...

Lymphatic filariasis leading to the passage of white urine or chyle is a rare manifestation in children. Filarial parasite infiltration abnormal lymphatic-urinary communication occurs with prolonged infection. The incubation period ranges from 5 20 yrs., thus relatively infrequent pediatric age group. Index suspicion should be high when child presents because subclinical filarial infection difficult recognize. Moreover, more pathognomonic clinical manifestations such as lymphoedema...

Fungal renal abscesses are rare entities associated with significant morbidity and mortality. Affected kidneys can have microabscess, pyelonephritis, pyonephrosis, or papillary necrosis.Herein, we reported an unusual case of a large abscess cause by Candida tropicalis in diabetic patient. The entity presented as lump the abdomen later was diagnosed to be on computed tomography scan. confirmed culture aspirate. successfully treated percutaneous drainage administration amphotericin B...

Dermatophytoses are infections of the skin, hair and nails, caused by dermatophytes, namely spp, Microsporum spp Epidermophyton floccosum. is an anthropophilic fungus, a frequent cause tinea capitis in Africa though some imported cases now been reported from Europe, Brazil, Australia USA. Untill now, 3 causing capitis, unguium, corporis North India 2 cruris south have reported, but this probably first case report onychomycosis India.

Abstract Background: Carbapenems are among the last resorts in managing multidrug-resistant bacterial infections. The rise resistance to carbapenems is a significant concern, and production of carbapenemases that inactivate drug most typical mode developed by bacteria. Carbapenemase-producing bacteria associated with higher morbidity spread faster than noncarbapenemase-producing Detection essential for epidemiological surveillance choosing efficient antimicrobial patient. Materials Methods:...

The main aim of this study is to determine the various types oral bacteria and yeast. Present in flora head neck cancer patients at different stages chemo-radiotherapy, compare it with control group (patients contralateral healthy mucosa). Seventy seven proven history squamous cell carcinoma were included study. mucosa profile was assessed for bacterial manifestations swab samples from both sites patients. grade mucositis charted out all during second third week radiotherapy. revealed that...

Cryptococcal infections (Cryptococcosis) are fatal fungal typically caused by Cryptococcus neoformans, a saprophyte frequently found in soil contaminated with pigeon droppings and seen immunocompromised (specifically HIV Positive) individuals. Now day’s awareness is emerging on cryptococcal disease among non-immunocompromised patients also. We present case of meningitis (CM) patient cardiopulmonary arrest. A 55 year old male came history headache fever neck rigidity since last 3 months. The...

Abstract Poster session 1, September 21, 2022, 12:30 PM - 1:30 Objectives Nuclear magnetic resonance (NMR) spectroscopy provides a holistic snapshot of the metabolome an organism. There is dearth studies till date that had exploited NMR metabolomic platform to study dermatophytes, despite its potential for rapid identification and subsequent application knowledge in performing faster antifungal susceptibility dermatophytes. Here we attempted frequency various species dermatophytes clinically...

Abstract Poster session 1, September 21, 2022, 12:30 PM - 1:30 Background Trichosporon spp are yeast-like organisms belonging to class Basidiomycetes which usually commensals. It can cause diseases ranging from superficial infection, commonly known as White Piedra, disseminated infections (Trichosporonosis). Cases of invasive Trichosporonosis have increased worldwide. has now become the second most common fungemia after Candida spp, especially in immunocompromised individuals. Methods We...

Abstract Poster session 3, September 23, 2022, 12:30 PM - 1:30 Objective Due to the ongoing COVID-19 pandemic a new group of patients at risk emerged with COVID-19-associated mucormycosis (CAM) and other fungal infections. Molecular studies, evaluating prevalence CAM infections are lacking. To assess in super-specialty healthcare hospital North India, we applied direct microscopy, culture, qualitative real-time-PCR targeting Mucorales-specific fragments on tissue specimens critically ill...

Malaria is a parasitic disease caused by and associated with acute febrile episodes. The burden highest in Southeast Asia. Various measures are being taken to curb the different countries. Even after introduction of various programmes there has been reports imported malaria which transported from highly endemic countries less or not having cases Malaria. Not only this, other viral come as coinfection makes situation even worse. Here we describe one such case traveller Nigeria India who also...