- Protein Structure and Dynamics
- Enzyme Structure and Function
- RNA and protein synthesis mechanisms
- Municipal Solid Waste Management
- Mass Spectrometry Techniques and Applications
- Protein Kinase Regulation and GTPase Signaling
- Vehicle Dynamics and Control Systems
- Biochemical and Molecular Research
- Wastewater Treatment and Reuse
- Electric Vehicles and Infrastructure
- DNA and Nucleic Acid Chemistry
- Bacteriophages and microbial interactions
- Biochemical effects in animals
- Real-time simulation and control systems
- Economic and Environmental Valuation
- Smart Cities and Technologies
- Hydraulic and Pneumatic Systems
- Crystallography and molecular interactions
- Environmental Education and Sustainability
- Molecular spectroscopy and chirality
- ATP Synthase and ATPases Research
- Electron Spin Resonance Studies
- Enzyme function and inhibition
- Recycled Aggregate Concrete Performance
- Signaling Pathways in Disease
Shanghai Normal University
2020-2023
Shenzhen Technology University
2022
Scripps Research Institute
2000
University of Toronto
1994-1997
Hospital for Sick Children
1994-1997
SickKids Foundation
1997
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComparison of the Backbone Dynamics a Folded and an Unfolded SH3 Domain Existing in Equilibrium Aqueous BufferNeil A. Farrow, Ouwen Zhang, Julie D. Forman-Kay, Lewis E. KayCite this: Biochemistry 1995, 34, 3, 868–878Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://pubs.acs.org/doi/10.1021/bi00003a021https://doi.org/10.1021/bi00003a021research-articleACS PublicationsRequest...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural Characterization of Folded and Unfolded States an SH3 Domain in Equilibrium Aqueous BufferOuwen Zhang Julie D. Forman-KayCite this: Biochemistry 1995, 34, 20, 6784–6794Publication Date (Print):May 23, 1995Publication History Published online1 May 2002Published inissue 23 1995https://pubs.acs.org/doi/10.1021/bi00020a025https://doi.org/10.1021/bi00020a025research-articleACS PublicationsRequest reuse permissionsArticle...
Measurements of 15N NMR relaxation parameters have been used to characterize the backbone dynamics folded and denatured states N-terminal SH3 domain from adapter protein drk, in high salt or guanidinium chloride, respectively. Values spectral density function evaluated at a number frequencies are compared. The levels show little variation across molecule similar magnitude those determined previously for state exchange with an unfolded low concentrations [Farrow et al. (1995) Biochemistry 34,...
The isolated N-terminal SH3 domain of the Drosophila adapter protein drk (drkN domain) exists in a dynamic equilibrium between folded (Fexch) and an unfolded (Uexch) state under native-like buffer conditions [Zhang, O., & Forman-Kay, J. D. (1995) Biochemistry 34, 6784−6794]. effect binding proline-rich peptide derived from Sos, biological target drkN domain, on this has been investigated. stabilization Fexch upon provides example link folding or stabilization. We have compared NMR parameters...
Waste management is an evolutionary system, but few studies have explored how and why public willingness to participate in waste separation changes, or possible paths increase residents' participate. This paper took Shanghai as a case study of city that has experienced recent environmental policy change embrace feedback perspective. The results showed after the implementation, resident's satisfaction with increased by only 5.3%, participation actually decreased 5.4%. A Geodetector model both...
Comprehensive NOE results from detailed structural characterization of a 131 residue partially folded fragment staphylococcal nuclease (Δ131Δ) made possible by NMR methods with improved resolution are presented. The resulting patterns reflect sampling both α and β regions φ, ϕ conformational space, yet demonstrate significant preferences for native-like non-native-like turn potentially helical conformations. Together data studies the unfolded state drkN SH3 domain, observed or proteins...
Building a digital and informative smart city is comprehensive application of new generation information technology, which can effectively improve the modernization city. Connected Vehicle greatly level urban intelligence in field transportation. In this paper, Vehicles are studied with ultimate goal cities. The construction technology route, system architecture connected cars studied, some practices project carried on DaLang town, LongHua district, Shenzhen to verify credibility architecture.
Path tracking is an important part of autonomous vehicles. Stanley algorithm widely used in path control front wheel steering The traditional calculates the angle according to relative geometric relationship between vehicle pose and reference point, which depends on nearest point. It suitable for low-speed small change curvature paths. In order improve accuracy stability algorithm, a model predictive based adaptive proposed, considers preview distance dynamics. comparative simulation...
The requirement of higher education is increasing in China caused by the development economics and growing population. Many universities enlarge their campus to meet demand abundant students which led longer commutes between two areas campus. Campus bus using an environmental friendly way increase commute efficiency have important significance realize carbon reduction target. This paper introduces a method design route taking Shenzhen Technology University (SZTU) as example.