Background To examine the association between potentially modifiable risk factors with cardiovascular disease (CVD) and all-cause mortality to quantify their population attributable fractions (PAFs) among a sample of Tehran residents. Methods Overall, 8108 participants (3686 men) aged≥30 years, were investigated. outcomes, multivariate sex-adjusted Cox proportional hazard regression analysis conducted, using age as time-scale in two models including general/central adiposity: 1)adjusted for...

Objective To investigate the population-based incidence of type 2 diabetes and its potential risk factors in a sex-split cohort Iranian population. Materials Methods A total 8400 non-diabetic participants, aged ≥20 years (3620 men 4780 women) entered study. Crude age standardized rates per 1000 person-years were calculated for whole population each sex separately. Cox proportional hazard models used to evaluate ratios (HR) 95% confidence intervals all both uni-variable multivariable models....

Abstract The purpose of this study was to introduce a new deep learning (DL) model for segmentation the fovea avascular zone (FAZ) in en face optical coherence tomography angiography (OCTA) and compare results with those device’s built-in software manual measurements healthy subjects diabetic patients. In retrospective study, FAZ borders were delineated inner retinal slab 3 × enface OCTA images 131 eyes 88 patients 32 18 subjects. To train convolutional neural network (CNN) model, 126 (104...

A fundamental part of prevention is prediction. Potential predictors are the sine qua non prediction models. However, whether incorporating novel to models could be directly translated added predictive value remains an area dispute. The difference between power a model with (enhanced model) and without (baseline certain predictor generally regarded as indicator by that predictor. Indices such discrimination calibration have long been used in this regard. Recently, use has suggested while...

To determine the minimum number of optical coherence tomography B-scan corrections required to provide acceptable vessel density measurements on angiography images in eyes with diabetic macular edema.In this prospective, noninterventional case series, center-involving edema were assessed. Optical imaging was performed using RTVue Avanti spectral-domain system AngioVue software (V.2017.1.0.151; Optovue, Fremont, CA, USA). Segmentation error recorded and manually corrected inner retinal layers...

Background To examine the trend of cardiovascular diseases (CVD) risk factors among a Middle Eastern population with prevalent CVD during median follow up 12 years. Methods Patients (n = 282, men 167), mean age 60.76 years were evaluated in four study phases TLGS (Tehran lipid glucose study), 2002–2005, 2005–2008, 2008–2011, and 2011–2014. Trends estimated using generalized estimation equation (GEE) models, by adjusting for gender, propensity scores. Result The adjusted prevalence general...

To examine the incidence rate of severe non-proliferative and proliferative diabetic retinopathy (severe-NPDR/PDR) determine its potential risk factors.

We herein present a rare case of acute central serous chorioretinopathy (CSC) associated with nonspecific orbital inflammation (NSOI). A 38-year-old woman presented 3-day history ocular pain, reduced vision, periorbital swelling, proptosis, conjunctival chemosis, and restricted eye movements. Optical coherence tomography the affected confirmed signs CSC. Additionally, computed scan revealed enlargement intraconal soft tissues lacrimal gland. Ocular ultrasonography detected posterior sclera...

To compare the area of foveal avascular zone (FAZ) in superficial and deep retinal layers using two different spectral-domain optical coherence tomography angiography (OCTA) devices.A cross-sectional comparative study was conducted to obtain macular OCTA images from healthy subjects Optovue RTVue XR Avanti (Optovue, Inc, Fremont, CA) Spectralis HRA+OCTA (Heidelberg Engineering, Heidelberg, Germany). Two independent trained graders measured FAZ automated slab segmentation. The were...

To report a case of Acute bilateral angle closure and Myopia following oral Cefixime therapy for pharyngitis.A 49-year-old man presented to the clinic with history aggravating ocular pain blurry vision in both eyes from 5 days ago. He was under treatment 400 mg twice day acute bacterial pharyngitis since last week. His refractive error -3.75 -4.25 diopters right left eye respectively. Intraocular pressure (IOP) 32 mm Hg 40 eye. Slit lamp examination gonioscopy showed shallow anterior chamber...

: An 11-year-old female patient with autoimmune hepatitis (AIH) was referred to our rheumatology clinic due her current musculoskeletal manifestations. The had been diagnosed AIH 3 months previously, based on jaundice and impaired liver function tests, she treated low-dose prednisolone azathioprine. She presented malaise, arthritis, a malar rash the face, oral ulcers. Laboratory tests revealed positive ANA/anti-dsDNA test. Liver biopsy showed chronic severe inflammatory activity, in favor of...

Background Chorioretinal coloboma is a congenital anomaly which can be present in clinical spectrum with possibility of significant influence on visual acuity. Optical coherence tomography (OCT) has been frequently used for the study chorioretinal coloboma. OCT angiography (OCTA), as non-invasive method taking high-resolution images vessels, improve our understanding developmental aspects this anomaly.Materials and methods This observational case series evaluated patients coloboma, who were...

Purpose To assess the role of upper blepharoplasty on probable reduction forehead horizontal lines and glabellar frowns in patients who underwent eyelid blepharoplasty.Design This is a prospective study 32 female with aged between 35 75 years standard blepharoplasty.Method Measurement mid brow to hairline distance (MBHLD) inter (IBD) were performed within 3 days before, 1 6 months after surgery. The surgeon reported extent their satisfaction about beneficial effect lid decreasing...

Two patients presented with sudden painless unilateral blurry vision. The first patient was a 57-year-old female, and the second 71-year-old male. medical history of significant for diabetes mellitus systemic hypertension. Funduscopy both revealed an unusual form RVO, occlusion three main veins retina, concomitant intraretinal hemorrhages, macular edema. An extensive ischemic retina found in fluorescein angiography patient. Retinal vein can present as some due to rare anatomic variation.