A growing number of published studies have recently demonstrated the role resection in overall survival (OS) for patients with gliomas. In this retrospective study, authors objectively investigated extent (EOR) OS low-grade gliomas (LGGs).Between 1998 and 2011, 190 underwent surgery LGGs. All surgical procedures were conducted under corticosubcortical stimulation. The EOR was established by analyzing pre- postoperative volumes on T2-weighted MRI studies. difference between preoperative tumor...

Ventriculoperitoneal shunting is a validated procedure for the treatment of idiopathic normal-pressure hydrocephalus. To select shunt-responsive patients, infusion and tap tests can be used. Only gait evaluated after to establish potential improvement. In this study, we present our Hydro-Real-Time Neuropsychological Testing protocol assess feasibility performing an ultra-fast assessment patients during test. We tested 57 test obtain real-time feedback on their cognitive status. Data were...

The brain network governing meditation has been studied using a variety of practices and techniques eliciting different cognitive processes (e.g., silence, attention to own body, sense joy, mantras, etc.). It is very possible that are subserved by largely, if not entirely, disparate networks. This assumption was tested conducting an activation likelihood estimation (ALE) meta-analysis neuroimaging studies, which assessed 150 foci from 24 experiments. Different ALE meta-analyses were carried...

Activity in frontocentral motor regions is routinely reported when individuals process action words and often interpreted as the implicit simulation of word content. We hypothesized that these neural responses are not invariant components processing but modulated by context which they evoked. Using fMRI, we assessed relative weight stimulus features (i.e., intrinsic semantics words) contextual factors, eliciting word-related sensorimotor activity. Participants silently read action-related...

We can predict how an object would look like if we were to see it from different viewpoints. The brain network governing mental rotation (MR) has been studied using a variety of stimuli and tasks instructions. By activation likelihood estimation (ALE) meta-analysis tested whether MR networks be modulated by the type stimulus (body vs. non-body parts) or instructions (motor imagery-based non-motor instructions). Testing for bodily non-bodily axis revealed bilateral sensorimotor bodily-related...

Language representation in the bilingual brain is result of many factors, which age appropriation (AoA) and proficiency second language (L2) are probably most studied. Many studies indeed compare early late bilinguals, although it not yet clear what role so-called critical period L2 is. In this study, we carried out coordinate-based meta-analyses to address issue inspect addition that AoA. After preliminary inspection (also very early) bilinguals' networks, explored specific activations...

Neuropsychological studies suggest that the human brain is endowed with two body representations: schema (BS), coding orientation of one's parts in space, and structural description (BSD), location relative to a standard body. We used fMRI disentangle neural mechanisms underlying these putatively distinct representations. Participants saw an arm or pot's handle (stimulus: arm, handle) rotated at different angles (angle: 30–150°). If stimulus was subjects were instructed imagine (1) rotating...

Despite intraoperative technical improvements, the insula remains a challenging area for surgery because of its critical relationships with vascular and neurophysiological functional structures.To retrospectively investigate morbidity profile in insular nonenhancing gliomas, special emphasis on volumetric analysis tumoral resection.From 2000 to 2010, 66 patients underwent surgery. All surgical procedures were conducted under cortical-subcortical stimulation monitoring. Volumetric scan was...

Classical cognitive theories hold that word representations in the brain are abstract and amodal, independent of objects' sensorimotor properties they refer to. An alternative hypothesis emphasises importance bodily processes cognition: representation a concept appears to be crucially dependent upon perceptual-motor relate it. Thus, understanding action-related words would rely same motor structures also support execution actions. In this context, simulation represents key component. Our...

OBJECTIVE Awake surgery and mapping are performed in patients with low-grade tumors infiltrating functional brain areas for which the greater resection, longer patient survival. However, extent of resection is subject to preservation cognitive functions, absence proper feedback during mapping, surgeon may be less prone perform an extensive resection. The object this study was real-time continuous assessment function tumor tissue that could infiltrate eloquent tissue. METHODS authors...

The primary motor cortex (M1) is traditionally implicated in voluntary movement control. In order to test the hypothesis that there a functional topography of M1 activation studies where it has been higher cognitive tasks we performed activation-likelihood-estimation (ALE) meta-analyses neuroimaging experiments reporting relation six categories for which was sufficient number include, namely imagery, working memory, mental rotation, social/emotion/empathy, language and auditory processing....

Abstract Background The role of surgery for incidentally discovered diffuse incidental low-grade gliomas (iLGGs) is debatable and poorly documented in current literature. Objective aim was to identify factors that influence survival patients underwent surgical resection iLGGs a large multicenter population. Methods Clinical, radiological, data were retrospectively analyzed 267 operated iLGG from 4 neurosurgical Centers. Univariate multivariate analyses performed predictors overall (OS) tumor...

Abstract We can predict how an object would look if we were to see it from different viewpoints by imagining its rotation. This essential human ability, called mental rotation (MR), guides individuals' actions constantly updating their environmental consequences. It is, however, still under debate whether the way in which our brain accomplishes this operation is dete r mined type of stimulus or rather a strategy. Here present neuropsychological evidence sustaining view that what matters...

The importance of the extent resection (EOR) has been widely demonstrated as main predictor for survival, nevertheless its effect on tumor related epilepsy is less investigated. A total 155 patients were enrolled after a first-line surgery supratentorial Diffuse Low Grade Gliomas (DLGGs). Postoperative seizure outcome was analyzed stratifying results by volumetric data and molecular markers according to 2016 WHO classification. Receiver operating characteristic (ROC) curves computed asses...

Mental rotation (MR) is sustained by a network of brain regions, including parietal, pre-motor and primary motor (M1) cortices. However it still not clear whether M1 recruited only when individuals mentally rotate hands or also enhanced MR non-body parts. Here we report two experiments in which the involvement letters was tested using TMS. In Experiments 1a 1b participants were asked to judge line drawings, depicting either letters, same mirror images each other (N = 112). Subjects presented...