A5043060037- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Child Nutrition and Water Access
- Evolution and Genetic Dynamics
- Global Maternal and Child Health
- Stress Responses and Cortisol
- Single-cell and spatial transcriptomics
- Healthcare Systems and Reforms
- DNA and Nucleic Acid Chemistry
- Geographic Information Systems Studies
- Plant Disease Resistance and Genetics
- Forensic and Genetic Research
- Race, Genetics, and Society
- Adipose Tissue and Metabolism
- Photovoltaic Systems and Sustainability
- Banana Cultivation and Research
- Plant Reproductive Biology
- Chromosomal and Genetic Variations
- Ethnobotanical and Medicinal Plants Studies
- Land Use and Ecosystem Services
- Seed and Plant Biochemistry
- Genetic Mapping and Diversity in Plants and Animals
- Urban and Rural Development Challenges
- Influenza Virus Research Studies
- Hemoglobinopathies and Related Disorders
New York University
2021-2025
Independent University
2021
Johns Hopkins University
2016
Abstract Setaria italica (foxtail millet), a founder crop of East Asian agriculture, is model plant for C4 photosynthesis and developing approaches to adaptive breeding across multiple climates. Here we established the pan-genome by assembling 110 representative genomes from worldwide collection. The composed 73,528 gene families, which 23.8%, 42.9%, 29.4% 3.9% are core, soft dispensable private genes, respectively; 202,884 nonredundant structural variants were also detected....
Influenza severity increases with age, hospitalization and mortality rates during seasonal influenza epidemics being higher in older men than age-matched women. As it is known that circulating testosterone levels decline males, we hypothesized reduced contributes to age-associated severity. A murine model was used test this hypothesis. men, concentrations were lower aged (18 mo) young (2 male C57BL/6 mice. Following inoculation virus (IAV), males experienced greater morbidity, clinical...
This paper examines OpenStreetMap data quality at different stages of a participatory mapping process in seven slums Africa and Asia. Data were drawn from an OpenStreetMap-based developed as part research project focusing on understanding inequalities healthcare access slum residents the Global South. Descriptive statistics qualitative analysis employed to examine following question: What is spatial collaborative remote achieved by volunteer mappers morphologically complex urban areas?...
Significance Some of the most spectacular adaptive radiations plants and animals occur on remote oceanic islands, yet such are preceded by founding events that severely limit genetic variation. How genetically depauperate founder populations give rise to phenotypic ecological diversity characteristic island is not known. We generated genomic resources for Hawaiian Metrosideros ––a hyper-variable radiation woody taxa—for insights into paradox radiations. posit divergent selection differential...
Selection is a fundamental evolutionary force that shapes patterns of genetic variation across species. However, simulations incorporating realistic selection along heterogeneous genomes in complex demographic histories are challenging, limiting our ability to benchmark statistical methods aimed at detecting and explore theoretical predictions. stdpopsim community-maintained simulation library already provides an extensive catalog species-specific population models. Here we present major...
The dispersal of rice (Oryza sativa) following domestication influenced massive social and cultural changes across South, East, Southeast (SE) Asia. history islands SE Asia, the role Taiwan Austronesian expansion in this process remain largely unresolved. Here, we reconstructed routes O. sativa ssp. japonica to northern Philippines using whole-genome resequencing indigenous landraces coupled with archaeological paleoclimate data. Our results indicate that found diverged from Indonesian as...
Objectives To survey on the availability and use of primary care services in slum populations. Design Retrospective, cross-sectional, household, individual healthcare provider surveys. Setting Seven sites four countries (Nigeria, Kenya, Pakistan Bangladesh). Participants Residents slums informal settlements. Primary secondary outcome measures consultation rates by type facility. Results We completed 7692 7451 adult 2633 child surveys across seven sites. The majority consultations were to...
Abstract Background Slums or informal settlements characterize most large cities in LMIC. Previous evidence suggests pharmacies may be the frequently used source of primary care LMICs but that pharmacy services are variable quality. However, on use and availability is very limited for slum populations. Methods We conducted household, individual, healthcare provider surveys qualitative observations seven sites four countries (Nigeria, Kenya, Pakistan, Bangladesh). All up to 1200 households...