A5006699498- Silicon Carbide Semiconductor Technologies
- Copper Interconnects and Reliability
- Semiconductor materials and devices
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Organometallic Complex Synthesis and Catalysis
- Chemical Synthesis and Analysis
- X-ray Diffraction in Crystallography
- Multicomponent Synthesis of Heterocycles
- Crystallization and Solubility Studies
- Cancer, Hypoxia, and Metabolism
- Asymmetric Hydrogenation and Catalysis
- Chemical Synthesis and Reactions
- Synthesis and Biological Evaluation
- Synthesis of Organic Compounds
- Metabolism, Diabetes, and Cancer
- Catalytic C–H Functionalization Methods
- Microwave-Assisted Synthesis and Applications
- Advanced ceramic materials synthesis
- Synthesis and Catalytic Reactions
- Catalytic Cross-Coupling Reactions
- Semiconductor materials and interfaces
- Enzyme Structure and Function
- Acoustic Wave Resonator Technologies
- Ferrocene Chemistry and Applications
National Council for Scientific Research
2006-2021
University of Alberta
2015-2017
Institut polytechnique de Grenoble
2016
Alberta Hospital Edmonton
2015
University of Saskatchewan
2015
Centre National de la Recherche Scientifique
2004-2012
Unité de catalyse et de chimie du solide de Lille
2011-2012
Université Lille Nord de France
2011-2012
Université de Lille
2011-2012
École Nationale Supérieure de Chimie de Lille
2011-2012
Abstract Growing device‐quality 3C‐SiC monocrystalline material is still an issue despite two decades of work dedicated to the subject. Using silicon as substrate generates too many defects in layers, owing lattice mismatch, while it very difficult control initial nucleation on α‐SiC so that 60° rotated domains are randomly formed. Herein, elaboration mono‐orientated layers a 6H‐SiC(0001) on‐axis, Si face using vapor–liquid–solid mechanism reported. This non‐conventional approach for growing...
Use of [<sup>18</sup>F]FDG-positron emission tomography (PET) in clinical breast cancer (BC) imaging is limited mainly by insufficient expression levels facilitative glucose transporter (GLUT)1 up to 50% all patients. Fructose-specific hexose GLUT5 represents an alternative biomarker for PET metabolism BC. The goal the present study was compare uptake characteristics selected hexose-based radiotracers murine BC model EMT6. Uptake 1-deoxy-1-[<sup>18</sup>F]fluoro-d-fructose...
An environment-friendly high-yielding method for the racemic and asymmetric diastereoselective preparation of indole alkaloids via Pictet–Spengler reaction is reported. The proceeds with short times under solvent-free microwave-irradiation conditions.
Two fluorinated fructose analogs are taken up by tumor cells in culture. Their high affinity for the transporter protein GLUT5 provides information on structural demands of its binding site, and suggests approaches towards new molecular imaging probes.
Systematic exploration of zirconocene (Cp2ZrII) chemistry since the 1980s has offered a wide range useful methods for organic synthesis. Many these reactions are stoichiometric in zirconium, and even if several catalytic known, development is continuing interest. In this paper, study i.e. alkyne dimerization cyclotrimerization, presented. These carried out by employing recently introduced lanthanide-originated equivalent. The use 10 mol % Cp2ZrCl2, together with La metal or mischmetall as...
The specificity characteristics of transporters can be exploited for the development novel diagnostic therapeutic probes. facilitated hexose transporter family (GLUTs) has a distinct set preferences monosaccharide substrates, and while some are expressed ubiquitously (e.g., GLUT1), others quite tissue specific GLUT5, which is overexpressed in breast cancer tissues). While these differences have enabled new molecular probes based upon hexose- tissue-selective uptake, substrate design...
Abstract An efficient and facile protocol to functionalize position C‐3 of 2,5‐anhydro‐ D ‐mannitol via diastereoselective ring opening a C 2 ‐symmetric epoxide 2,5:3,4‐dianhydro‐ ‐allitol 3 has been developed. This method is protecting‐group‐free, high‐yielding, provides access C‐3‐modified ‐mannitols 5a , 11a – 15a 16 17 . was then extrapolated the synthesis aziridine, which underwent with various nucleophiles provide C‐3‐ C‐4‐modified 19 27 in excellent global yields moderate good...
The importance of the hydrogen bonding interactions in GLUT-hexose binding process (GLUT=hexose transporter) has been demonstrated by studying structurally modified d-fructose analogues to GLUTs, and one case its transport into cells. presence a bond donor at C-3 position 2,5-anhydro-d-mannitol derivatives is essential for effective GLUT5 tumor Surprisingly, installation group that can function only as acceptor resulted selective recognition GLUT1 rather than GLUT5. A fluorescently labelled...
The resonances of phonon and plasmon modes make the absorbance coefficient materials tremendously high in mid-infrared spectral range, which allows for a excitation laser to heat surface layers these with efficiency. Furthermore, scattering by defects defect-induced localized vibrational affect local infrared dielectric function and, hence, absorption coefficient. In this paper, we present photothermal beam deflection technique that takes advantage strong interaction between optical...
Five-membered zirconacycles were generated in a new way, by simultaneously reducing Cp2ZrCl2 and di- or tetrahalogenoalkanes with La mischmetall (an alloy of lanthanides) at room temperature. Zirconacyclopentane, formed using 1,2-diiodoethane as an ethylene source, underwent ligand exchange diphenylacetylene to afford the corresponding zirconacyclopentene zirconacyclopentadiene complexes. Reaction monitoring GC-MS spectroscopy indicated that not only did usual occur but also direct...