A5003181684- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Helminth infection and control
- Analytical Methods in Pharmaceuticals
- Global Maternal and Child Health
- Drug Solubulity and Delivery Systems
- Ethnobotanical and Medicinal Plants Studies
- Parasitic infections in humans and animals
- Pharmaceutical studies and practices
- Metabolism and Genetic Disorders
- Public Health in Brazil
- Vector-borne infectious diseases
- Mediterranean and Iberian flora and fauna
- Biological Control of Invasive Species
- Cultural, Media, and Literary Studies
- Bone and Dental Protein Studies
- Lepidoptera: Biology and Taxonomy
- Skin Diseases and Diabetes
- Literature, Culture, and Criticism
- Cholinesterase and Neurodegenerative Diseases
- Crystallization and Solubility Studies
- Identification and Quantification in Food
- Computational Drug Discovery Methods
- Pharmacogenetics and Drug Metabolism
- Insects and Parasite Interactions
Universidade Nova de Lisboa
2014-2024
Santa Casa de Misericórdia de Marília
2018
Instituto de Investigação Científica Tropical
2017
Instituto de Biologia Experimental e Tecnológica
2015
Inducing apoptosis is an interesting therapeutic approach to develop drugs that act against helminthic parasites. Researchers have investigated how curcumin (CUR), a biologically active compound extracted from rhizomes of Curcuma longa, affects Schistosoma mansoni and several cancer cell lines. This study evaluates CUR influences the induction oxidative stress in couples adult S. worms. decreased viability worms killed them. The tegument parasite suffered morphological changes, mitochondria...
Physella acuta is an invasive freshwater snail with a global distribution and recognized role as intermediate host for various trematodes, including Echinostoma spp. Trichobilharzia physellae. In Portugal, P. commonly found in bodies such Lake Alqueva, the largest artificial reservoir Europe. The lake's creation has altered local ecosystems, influencing populations migratory bird activity, which may contribute to dispersal of trematode parasites. While present region, its transmission...
Vernonia britteniana Hiern. (Asteraceae) is a medicinal plant used in traditional Angolan medicine against schistosomiasis. Our study aimed to investigate the phytochemical composition and cercaricidal antioxidant activities vitro of herbal preparation (Water-Vbr) 70% hydroethanolic extract (EtOH70%-Vbr) prepared with this plant. The activity extracts Schistosoma mansoni cercariae was assessed at different concentrations (500, 438, 125 µg/mL) time intervals, profiles were obtained by...
Introdução: Os meningiomas são os tumores primários do sistema nervoso central mais prevalentes. Mais frequentes nas mulheres, podem apresentar receptores de hormônios sexuais e ter sua evolução clínica influenciada por esses hormônios.
Schistosomiasis is a chronic neglected tropical disease saddling millions of people in the world, mainly children living poor rural areas. Praziquantel (PZQ) currently only drug used for treatment and control this disease. However, extensive use has brought concern about emergence PZQ-resistance/tolerance by Schistosoma mansoni . Studies spp. genome, transcriptome, proteome are crucial to better understand situation. In vitro study, we compare proteomes S. variant strain stably resistant PZQ...
Background Mozambique is one of the countries with highest prevalence schistosomiasis, although there little data on disease and associated morbidity in adult population. This study aimed to describe characterize schistosomiasis population Chókwè district explore use anamnestic questionnaires urine dipsticks, as well point-of-care ultrasound for urinary related findings, better morbidity. Methodology Between April October 2018, we conducted a cross-sectional embedded within Health Research...
Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. It neglected tropical disease, in which almost 240 million people are infected worldwide and about 700 at risk acquiring infection. The transmission has been reported 78 countries. An accurate diagnosis schistosomiasis essential for treatment control programs. However, diagnostic techniques may have some sensitivity limitations, especially mild infections, with low egg elimination rates. Therefore, present...
Toxocariasis is one of the most widespread and important zoonotic parasitic diseases, although neglected. Data regarding human Toxocara infection in Portugal are almost absent. This article gives an overview situation toxocariasis over last decade based on casuistic data. A total 846 serum samples from individuals suspected toxocariasis, collected 2010 to 2020, were analyzed at Institute Hygiene Tropical Medicine. Sera tested for IgG antibodies canis excreted-secreted larval antigens by...
Abstract Schistosomiasis is a parasitic disease caused by flatworms of the genus Schistosoma. Among Schistosoma species known to infect humans, S. mansoni most frequent cause intestinal schistosomiasis in sub-Saharan Africa and South America: World Health Organization estimates that about 200,000 deaths per year result from alone. The life cycle requires two different hosts: snail as intermediate host mammal definitive host. People become infected when they come into contact with water...
The goal of this research project was the optimization a method for simultaneously screen dissolution rate and permeability drug formulations across Polyvinylidene Fluoride membranes, using bilateral flow cell. Initially, effect several variables tested on caffeine acetylsalicylic acid permeability. obtained results showed that is more reproducible when cell used with unilateral at donor side stirring acceptor side. It also able to detect influence pH (caffeine Papp 7,4...