High-grade conduction disturbances requiring permanent pacemaker (PPM) implantation occur in up to 40% of patients following transcatheter aortic valve (TAVI). The aim this study was identify pre-operative risk factors for PPM after TAVI with the Medtronic CoreValve prosthesis (CVP). We retrospectively analysed 109 transfemoral CVP performed between 2008 and 2009 at Leipzig Heart Center. Patients who had indwelling time (n = 21) were excluded, leaving 88 analysis. Mean age 80.3 ± 6.6 years...

Minimally invasive techniques are progressively challenging traditional approaches in cardiothoracic surgery. aortic valve replacement (AVR) has become a routine procedure at our institution.We retrospectively analyzed all patients undergoing minimally isolated AVR between January 2003 and March 2014, institution. Mean follow-up was 4.7±4.3 years (range: 0-18 years) 99.8% complete.There were 1,714 who received an AVR. The mean (± SD) patient age 65±12.8 years, ejection fraction 60%±12% log...

Few studies have focussed on the outcomes of tricuspid valve (TV) repair in patients with a right ventricular permanent pacemaker lead (PPL) and regurgitation (TR).Retrospective analysis all PPL undergoing TV (annuloplasty ring 83 De Vega annuloplasty 33 patients) between April 2001 May 2008 (n=116) was performed. The mean patient age 71 ± 8.8 years; 59.8% were female, average European System for Cardiac Operative Risk Evaluation (EuroSCORE) 16.4 14.5%. Follow-up 100% complete duration 19.4...

Single mouse cardiomyocytes were exposed to defined ischemia. We designed chambers on glass chips with a volume of 192 pL (picochambers). After picochamber was loaded single cardiomyocyte, P o 2 in the equilibrated that headspace, where it controlled critical range between <0.2 and 10 mm Hg. Because extracellular fluid restricted, these conditions are close tissue Responses sarcolemmal K ATP -channel current ( I KATP ), production reactive oxygen species (ROS), mitochondrial membrane...

Abstract OBJECTIVES Elective treatment of aortic valve disease by transcatheter replacement (TAVR) is becoming increasingly popular, even in patients with low risk and intermediate risk. Even a bicuspid (BAV) are considered eligible for TAVR. Permanent pacemaker implantation (PMI) known—frequently understated—complication TAVR affecting 9–15% potentially significant impact on longevity quality life. BAV affected the highest PMI rates, although they frequently younger compared to their...

Abstract Introduction Acute graft failure is the leading cause of early mortality after heart transplantation ( HTx ). Extracorporeal membrane oxygenation ECMO ) an efficient therapeutic option to treat various pathologies, unburden left and right ventricle, allow for functional recovery transplanted heart. We reviewed our experience outcomes in patients. Methods Retrospectively, we analyzed all patients who received orthotopic HT x (n = 298) department over a 15‐yr period (1997 through...

Postinfarction ventricular septal defect (pVSD) due to acute myocardial infarction complicated by cardiogenic shock (CS) is associated with high mortality. The aim of this study was determine the outcome primary surgical repair pVSD in patients CS and examine whether it influenced use mechanical circulatory support (MCS) devices. Between October 1994 April 2016, performed 53 patients. Thirty-six (68%) were implanted pre-operatively an intra-aortic balloon pump (IABP), 4 (8%) extracorporeal...

Lung hernia following minimally invasive mitral valve surgery is an uncommen entity. We report the case of a male patient who developed lung as sequela to limited access surgery. Two months after discharge, presented with bulge in region lateral thoracotomy related respiration which could be provoked by Valsalva maneuver. In night admission had acute cardiovascular decompensation worsening dyspnea, pallor and hypotension. The was quickly transferred ICU, where chest X-ray revealed presence...

Pacemaker implantation using endocardial leads can give rise to thrombotic venous occlusion. We report the case of a 23-year-old male with transposition great arteries, who had previously undergone Senning repair at age one year. A sick sinus syndrome required pacemaker subsequent multiple lead revisions. Following last lead, patient developed complete occlusion inferior vena cava (IVC) stenosis superior (SVC) in both lesions. Liver failure, ascites and esophageal varices developed....

In recent years, catheter-based aortic valve interventions have become established procedures for the treatment of high-risk and advanced age patients with pathologies. One limitations widespread applicability this procedure is annulus size. Until recently, no prosthesis was available to treat a large annulus. We report on patient high-grade stenosis (AS) 27-mm annulus, who underwent transapical implantation (TAP) an Edwards SAPIEN® 29-mm (Edwards LifeScience, Irvine, CA, USA). Due...

Background: Mediastinitis after cardiac surgery can lead to devastating consequences such as deep sternal wound infections (DSWI). Staphylococcus epidermidis and other coagulase-negative staphylococci belong the physiological skin flora therefore generally are not considered pathogenic agents. Thus, local resistance patterns of these bacterial species often recovered from specimens ignored while choosing antibiotics for peri-operative prophylaxis in well selection empiric antibiotic therapy...

Bradycardic arrhythmias requiring pacemaker (PM) implantation are still common in patients need of tricuspid valve replacement (TVR). Leaving an existing PM lead extravalvular position may represent a helpful alternative special situations like the mechanical TV. This study aimed to examine short- mid-term outcome paravalvular leads concerning survival and prosthesis dysfunction after TVR.A retrospective case-control with TVR ventricular pacing was conducted. Patients from database Leipzig...

Current trends towards permanent downhole instrumentation allow the acquisition of large sets well test data ranging over much longer periods time than previously imaginable. Such can contain information about reservoir at a substantially larger radius investigation that accessible to conventional derivative analysis, which is limited interpretation single flow constant rate. By contrast, deconvolution methods do not suffer from this constraint as they are designed perform analysis variable...

Clostridium difficile (CD) is the most common pathogen causing nosocomial diarrhea. The clinical presentation ranges from mild diarrhea to severe complications, including pseudomembranous colitis, toxic megacolon, sepsis, and multi-organ failure. When disease takes a fulminant course, death ensues rapidly in complex cases. Preventive screening or current prophylactic therapies are not useful. Therefore, this study was conducted detect risk factors for CD infection (CDI) patients undergoing...

Objective: The aim of the study was to clarify question, whether combination ECMO and IABP has positive or negative effects on coronary circulation.

Four days after uncomplicated implantation of a two-chamber pacemaker and normal postoperative course, patient was referred to our hospital with left-sided hemothorax early hemorrhagic shock. Chest X‐ray CT scan were suspicious right ventricular lead perforation additional pericardial pleural injury. Immediate surgery performed via lateral thoracotomy the repaired direct suture. An epimyocardial implanted simultaneously. The made an uneventful recovery.

Atrial fibrillation has a significant impact on patient mortality and morbidity. In particular, stroke is frequent complication associated with atrial fibrillation. recent years, various treatment options have been developed that are based the elimination of atypical electrically active areas. Areas covered: This manuscript presents new cryoablation probe from AtriCure Inc. addition to describing characteristics probe, we also discuss its surgical therapy as well basics cryosurgery. The...