- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- HIV/AIDS oral health manifestations
- Oral and gingival health research
- Periodontal Regeneration and Treatments
- Oral Health Pathology and Treatment
- Protease and Inhibitor Mechanisms
- Dental Radiography and Imaging
- Dental Research and COVID-19
- Pediatric health and respiratory diseases
- Dental Implant Techniques and Outcomes
- Scientific and Engineering Research Topics
- Congenital Heart Disease Studies
- Salivary Gland Disorders and Functions
- Dental Education, Practice, Research
- Infective Endocarditis Diagnosis and Management
- Birth, Development, and Health
- Cardiac Valve Diseases and Treatments
- Diversity and Career in Medicine
- Pneumonia and Respiratory Infections
- Reproductive tract infections research
- Infant Nutrition and Health
- Muscle and Compartmental Disorders
- Health, psychology, and well-being
- Smoking Behavior and Cessation
Obafemi Awolowo University
2015-2025
Obafemi Awolowo University Teaching Hospitals Complex
2023
University of Helsinki
2019
Finnish Society of Sciences and Letters
2018
University of Abuja
2013-2014
University of Abuja Teaching Hospital
2013-2014
The aim of this study was to investigate the utility incorporating active matrix metalloproteinase-8 (aMMP-8) as a biomarker into new periodontitis classification system (stage/grade) presented in 2018. This included 150 Greek adults aged 25-78, whom 74 were men and 76 women. Participants tested with an aMMP-8 point-of-care mouthrinse test, after which full-mouth clinical examination performed assess their periodontal oral health. levels significantly lower among healthy patients compared...
Background: Matrix metalloproteinase (MMP)‐8 is a major destructive collagenase involved in periodontitis and can be regarded as biomarker. A neutrophil 2 (active MMP‐8 [aMMP‐8]) oral fluid immunoassay has recently been demonstrated to risk indicator among adults. The aim of this study investigate whether point‐of‐care mouthrinse test based on an aMMP‐8 could identify patients with inflammatory burden (periodontitis caries) adolescents early pathologic findings. Methods: This cross‐sectional...
The aim of the present study is to investigate clinical correlates a novel lateral-flow immunoassay with bleeding on probing (BOP), oral hygiene, and periodontal depth. This report offers simple, rapid, highly sensitive tool that addresses two issues important periodontists: 1) detecting active periodontitis, 2) predicting chronic periodontitis.Seventy-six 86 males requiring seminal fluid analysis as part separate were serially recruited into study. After basic dental examination under...
This communication article addresses currently available rapid non-invasive methods to screen and detect periodontitis dental peri-implantitis. In this regard, oral fluid biomarkers have been researched extensively but self-reported health (SROH)-questionnaires also developed. Both alternatives may offer a quick easy way diseased patients. Active matrix metalloproteinase (aMMP-8) is one of the most validated for screening detecting periodontal breakdown related peri-implantitis monitoring...
Abstract Objective The aim of this study was to determine the diagnostic utility an MMP‐8 biosensor assay in differentiating periodontal health from gingivitis and periodontitis compare it with established time‐resolved immunofluorescence (IFMA) enzyme‐linked immunosorbent (ELISA). Background Currently available antibody‐based assays display a wide variability their ability accurately measure matrix metalloproteinase‐8 (MMP‐8) levels saliva. Methods Salivary were analyzed 189 systemically...
This study assessed the practice of disposing waste from eight dental clinics Obafemi Awolowo University Teaching Complex, Ile-Ife, Nigeria. All cleaners (14) in hospitals were surveyed through questionnaire. Information obtained included socio-economic characteristics (biodata), personal protection, facilities available for them to work with and job satisfaction. Two soil samples open dump site (0.15 0.30 m depth) two water also collected (at 0.00 50.00 m) within vicinity site. Both taken...
Periodontal disease is a chronic multifactorial infectious and inflammatory associated with several systemic diseases, such as diabetes, cardiovascular diseases (CVD), obstructive pulmonary disease, hypertension, Alzheimer's so on. These same have been severe COVID-19 infections. Several recent studies suggested hypotheses for the potential association between periodontal COVID-19. also one of most prevalent globally. All this supports importance good oral health, in era. Thus, new...
Background: Different studies have looked at the effect of periodontitis on chronic kidney disease but only few evaluated severities Chronic Kidney Disease (CKD) especially among predialysis patients. This study revealed association between and CKD patients findings from this may be applied to management Methods: A cross-sectional involving 120 pre-dialysis participants. Full periodontal examination was carried out participants assessed using American Academy Periodontology, 2005...
Background/Objectives: Previous research indicates that non-surgical periodontal therapy (NSPT) improves glycemic control in individuals with prediabetes and diabetes who have periodontitis. Few studies demonstrated its effects on mouthrinse active-matrix metalloproteinase-8 (aMMP-8) levels as it relates to control. We assessed the treatment response of stage II–IV periodontitis patients prediabetes, diabetes, normoglycemia, regarding glycated hemoglobin (HbA1c) aMMP-8 using point-of-care...
Abstract Objectives: 1. To investigate the relationship between periodontitis and infertility. 2. evaluate importance of oral hygiene to general health. Materials methods Eighty-six men requiring seminal fluid analysis as part an on-going investigation for infertility in their spouses were serially recruited into study. Basic dental periodontal examination performed. Each participant was also screened using a lateral flow immunoassay kit which detected levels active membrane...
Chronic periodontitis is gaining increasing prominence as a potential influnce on systemic health. Time to conception has been recently investigated in relation chronic among Caucasians. The authors set out replicate the study Nigerian pregnant women.The etiology of many medical conditions have linked with state oral health and one such time (TTC) women. This was aimed assess effect TTC.A cross-sectional hospital setting involving 58 fertility clinic attendees 70 controls using simplified...
Abstract: Periodontal diseases that affect the marginal and apical periodontium result from interaction between bacterial biofilm host response. Oral fluid biomarkers might aid clinical diagnosis. Matrix metalloproteinases (MMPs) are a family of 24 proteases act in physiological pathological conditions. They can degrade almost all extracellular matrix constituents regulate inflammatory processes. mainly inhibited by tissue inhibitors metalloproteinases. The aim this study was to perform...
Terms relating to pigmentation of the oral mucosa include physiologic (racial) pigmentation, pigmented nevi, melanotic maculae, melanoma, and smokers' melanosis. The literature is replete with studies about mucosal which thought result from melanin incontinence. documented etiological factors are both local systemic hormones, drugs, smoking, idiopathic causes. This study investigated prevalence melanosis among Nigerian smokers controls who were non-smokers.A total 1270 sites examined in 253...
Introduction: it has been close to four years since the authors highlighted total neglect of oral health street children in Journal Public Health Policy. Since then, authorities appear have simply turned blind eye making this follow-up imperative. This report specifically examines resultant disparity between Nigeria's and Private, fee-paying secondary school students Northern Nigeria.