- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Dental Health and Care Utilization
- Dental Radiography and Imaging
- HIV/AIDS oral health manifestations
- Oral and gingival health research
- Periodontal Regeneration and Treatments
- Salivary Gland Disorders and Functions
- Dental Implant Techniques and Outcomes
- Immune Response and Inflammation
- Dental Erosion and Treatment
- Endodontics and Root Canal Treatments
- Smoking Behavior and Cessation
- Streptococcal Infections and Treatments
- Dental Research and COVID-19
- Dental Education, Practice, Research
- Advanced Glycation End Products research
- Head and Neck Cancer Studies
- Bone health and treatments
- Diabetes Management and Education
- Patient-Provider Communication in Healthcare
- Pediatric health and respiratory diseases
- Dental materials and restorations
- Bone and Joint Diseases
- Diabetes and associated disorders
Newcastle University
2013-2025
University of Dundee
2021-2025
National University of Singapore
2019-2024
British Society of Periodontology
2024
Dundee Dental Hospital
2024
Newcastle Dental Hospital
1997-2019
Newcastle upon Tyne Hospital
2003-2017
Newcastle College
2008-2017
University of Newcastle Australia
2005-2015
The Ohio State University
1998-2009
Abstract Background A variety of systemic diseases and conditions can affect the course periodontitis or have a negative impact on periodontal attachment apparatus. Gingival recessions are highly prevalent often associated with hypersensitivity, development caries non‐carious cervical lesions exposed root surface impaired esthetics. Occlusal forces result in injury teeth Several developmental acquired prostheses may predispose to periodontium. The aim this working group was review update...
Dysbiotic oral bacterial communities have a critical role in the etiology and progression of periodontal diseases. The goal this study was to investigate extent which smoking increases risk for disease by influencing composition subgingival microbiome states clinical health. Subgingival plaque samples were collected from 200 systemically periodontally healthy smokers nonsmokers. 16S pyrotag sequencing preformed generating 1,623,713 classifiable sequences, compared with curated version...
Abstract Background Over the last two decades, progress in prevention and treatment of caries periodontal diseases has been translated to better oral health improved tooth retention adult population. The ageing population increasing expectations good health‐related quality life older age pose formidable challenges clinical care healthcare systems. Aims objective this workshop was critically review scientific evidence develop specific recommendations to: (i) prevent loss retain function...
Abstract Background: Major challenges in periodontology include understanding the pathophysiology, interplay between various components of host response, parallels with other diseases and identifying biomarkers disease. Objectives: Four reviews were compiled aim better understanding: (1) role polymorphic nuclear leucocytes (PMNs), i.e. neutrophils; (2) function cytokine networks response; (3) whether exist rheumatoid arthritis (RA); (4) useful currently to help management periodontal...
Summary Interleukin‐33 (IL‐33) is an IL‐1 family cytokine that has a role in regulating T helper type 2 cytokines and mast cell development. Expression of IL‐33 also associated with chronic inflammatory conditions such as rheumatoid arthritis. However, there little information regarding myeloid immune responses, which are important immunity inflammation. We therefore investigated the expression, intracellular location regulation by lipopolysaccharide (LPS) from Escherichia coli periodontal...
Novel nicotine products, particularly electronic cigarettes (e-cigarettes), have become increasingly popular over the past decade. E-cigarettes are sometimes regarded as a less harmful alternative to tobacco smoking, and there is some evidence of their potential role smoking cessation aid. However, concerns about health consequences, in users who not smokers, also when used long term. Given mode delivery these for oral consequences. Over few years, been an increasing number studies conducted...
Abstract Aims To assess the impact of periodontal treatment on systemic inflammation in type 2 diabetes. Materials and Methods Adults with diabetes ( n = 83) without (controls, 75) were recruited, participants periodontitis received 12 months’ follow‐up. Biomarkers for (gingival crevicular fluid interleukin‐6, tumour necrosis factor‐α, interleukin‐1β, interferon‐γ, matrix metalloproteinase‐8, metalloproteinase‐9, adiponectin) serum markers control (glycated haemoglobin, high sensitivity...