- Health disparities and outcomes
- Global Health Care Issues
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Obesity and Health Practices
- Chronic Disease Management Strategies
- Prostate Cancer Treatment and Research
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrest and Resuscitation
- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Global Public Health Policies and Epidemiology
- Global Health Workforce Issues
- Cervical Cancer and HPV Research
- Infant Development and Preterm Care
- Metabolism and Genetic Disorders
- Food Security and Health in Diverse Populations
- Neonatal Respiratory Health Research
- Prostate Cancer Diagnosis and Treatment
- Nutrition and Health in Aging
- Healthcare Policy and Management
- Leprosy Research and Treatment
- HER2/EGFR in Cancer Research
- COVID-19 Impact on Reproduction
- Hormonal and reproductive studies
Nenagh Hospital
2019-2025
Health Service Executive
2009-2024
BioMarin (United States)
2023-2024
IQVIA (United States)
2020
ZSX Medical (United States)
2017-2018
Genomic Health (United States)
2015-2018
ZOLL Medical Corporation (United States)
2018
University College Cork
2013-2015
University of Copenhagen
2013
Siberian Branch of the Russian Academy of Sciences
2013
Overweight and obesity prevalence has risen dramatically in recent decades. While it is known that overweight associated with a wide range of chronic diseases, the cumulative burden disease population not well quantified. The aims this paper were to examine associations between BMI prevalence; calculate Population Attributable Fractions (PAFs) obesity; estimate impact one unit reduction on disease. A cross-sectional analysis 10,364 adults aged ≥18 years from Republic Ireland National Survey...
Abstract Background C-reactive protein (CRP) and Serum amyloid A (SAA) increases with systemic inflammation are related to worse survival for breast cancer survivors. This study examines the association between percent body fat SAA CRP potential interaction NSAID use weight change. Methods Participants included 134 non-Hispanic white Hispanic survivors from Health, Eating, Activity, Lifestyle Study. Body percentage, measured Dual Energy X-ray Absorptiometer (DEXA), circulating levels of were...
Abstract Background Respiratory syncytial virus (RSV) is the world's leading cause of viral acute lower respiratory infections (ALRI) in infants. WHO has identified maternal RSV vaccination a priority and candidate vaccines are development; however, vaccine hesitancy remains an impediment to successful implementation immunization. This study, largest antenatal survey conducted to‐date, aimed examine awareness, likely acceptance pregnancy, attitudes vaccination. Methods Pregnant women all...
The increasing prevalence of overweight and obesity worldwide continues to compromise population health creates a wider societal cost in terms productivity loss premature mortality. Despite extensive international literature on the obesity, findings are inconsistent between Europe USA, particularly within Europe. Studies vary issues focus, specific costs methods. This study aims estimate healthcare for island Ireland 2009, using both top-down bottom-up approaches.Costs were estimated across...
Cervical cancer is a leading cause of death worldwide, and in Ireland it the ninth most commonly diagnosed women. Almost 100% these cancers are caused by human papillomavirus (HPV) infection. Two newly developed vaccines against HPV infection have become available. This study cost-utility analysis vaccine Ireland, compares cost-effectiveness profiles two vaccines.A was performed using Markov model. A cohort screened vaccinated women compared with an unvaccinated cohort, both cohorts were...
Mumps is a contagious vaccine-preventable viral disease that experiencing revival in students attending second and third level colleges. Large mumps outbreaks have been reported several countries despite the presence of childhood immunisation programmes over many years, including measles, mumps, rubella (MMR) vaccination. In 2008, 1,377 cases were notified Ireland 1,734 first three months 2009 (provisional data). This paper reviews recent epidemiology Mid-West region highlights preventive...
Phenylketonuria (PKU), a genetic disorder characterized by phenylalanine hydroxylase (PAH) deficiency and (Phe) accumulation, is primarily managed with protein-restricted diet PKU-specific medical foods. Pegvaliase an enzyme substitution therapy approved for individuals PKU uncontrolled blood Phe concentrations (>600 μmol/L) despite prior management. This analysis assessed the effect of pegvaliase on dietary intake using data from Phase 3 PRISM-1 (NCT01819727), PRISM-2 (NCT01889862), 165-304...
This case report details the public health response to a multibacillary leprosy in Ireland. The presented with hypopigmented skin lesions and neurological symptoms. Challenges included delayed recognition clinical setting, contact tracing within congregate setting lack of specific Irish guidelines. Comprehensive tracing, chemoprophylaxis follow-up care were implemented, guided by international protocols. underscores need for tailored guidelines stigma mitigation strategies this neglected...
Socially excluded groups of people (SEP) live with resources so inadequate that it precludes them from participating fully in the normal acceptable living standards society. They often have complex health and social care needs yet face structural attitudinal barriers accessing mainstream healthcare. This can result ambulatory-care sensitive conditions being left untreated community contributes to higher use costly acute services crisis mode by SEP. Tailored inclusion primary (SIPC) provide a...
Objectives This study sought to examine the relationship between temperature at reperfusion and infarct size. Background Hypothermia consistently reduces size when administered prior in animal studies, however, clinical results have been inconsistent. Methods We performed a patient‐level pooled analysis from six randomized control trials of endovascular cooling during primary percutaneous coronary intervention (PCI) for ST‐segment elevation myocardial infarction (STEMI) 629 patients which...
Background: Given the scale of current obesity epidemic and associated health consequences there has been increasing concern about economic burden placed on society in terms direct healthcare costs indirect societal costs.In Republic Ireland these were estimated at €1.13 billion for 2009.The total six major related conditions (coronary heart disease & stroke, cancer, hypertension, type 2 diabetes knee osteoarthritis) same year €2.55 billion.The aim this research is to project 2030 using...
<h3>Objectives:</h3> To determine the average cost of a case genital warts, for both males and females, with view to informing current debate as which Human papillomavirus vaccine would have maximum cost-effectiveness in Irish population. <h3>Methods:</h3> Contact time between patients healthcare professionals was prospectively measured at five genitourinary medicine clinics south-west Ireland, over period 3 weeks. By identifying all those it possible calculate proportion total taken by this...
To compare the ability of loss phosphatase and tensin homolog (PTEN) Genomic prostate score assay (GPS) in predicting biochemical-recurrence (BCR) clinical-recurrence (CR) after radical prostatectomy (RP) for clinically localized cancer (PCa).Three hundred seventy seven patients with without CR were retrospectively selected by stratified cohort sampling design from RP database. PTEN status (by immunohistochemistry [IHC] fluorescence situ hybridization [FISH]) GPS results determined...
Abstract Since the outbreak of war in Ukraine, over 78,000 migrants have come to Ireland seeking protection. It is necessary capture their demographics, understand immediate health concerns and identify additional service requirements ensure that this cohort can continue shelter healthily Ireland. A retrospective analysis was carried out on Health Needs Assessments (HNAs) undertaken for BOTPs congregated settings. Date entry captured 1820 HNA forms returned Department Public Mid-West Area E....