A5000944221- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Breast Lesions and Carcinomas
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Breast Cancer Treatment Studies
- AI in cancer detection
- Digital Radiography and Breast Imaging
- Global Cancer Incidence and Screening
- Advanced Neuroimaging Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Occupational and environmental lung diseases
- BRCA gene mutations in cancer
- Cancer Research and Treatments
- Medical Imaging and Pathology Studies
- Lanthanide and Transition Metal Complexes
- Photoacoustic and Ultrasonic Imaging
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Breast Implant and Reconstruction
- Cancer and Skin Lesions
- Ultrasound Imaging and Elastography
- Cancer, Hypoxia, and Metabolism
- Ultrasound and Hyperthermia Applications
Medical University of Vienna
2016-2025
Vienna General Hospital
2012-2024
Karl Landsteiner University of Health Sciences
2024
Memorial Sloan Kettering Cancer Center
2015-2024
King Abdullah Medical City
2023
Klinik und Poliklinik für Nuklearmedizin
2016-2023
University of Vienna
2001-2020
Christian Doppler Laboratory for Thermoelectricity
2017-2019
University of Messina
2018
Gender Studies
2017
Artificial intelligence (AI) systems performing at radiologist-like levels in the evaluation of digital mammography (DM) would improve breast cancer screening accuracy and efficiency. We aimed to compare stand-alone performance an AI system that radiologists detecting DM.Nine multi-reader, multi-case study datasets previously used for different research purposes seven countries were collected. Each dataset consisted DM exams acquired with from four vendors, multiple radiologists' assessments...
To evaluate the breast cancer screening efficacy of mammography, ultrasound, and magnetic resonance imaging (MRI) in a high-risk population various subgroups.In single-center, prospective, nonrandomized comparison study, BRCA mutation carriers women with high familial risk (> 20% lifetime risk) for were offered MRI every 12 months. Diagnostic performance was compared between individual modalities their combinations. Further comparisons based on subpopulations dichotomized by rounds, status,...
To compare the diagnostic quality of diffusion-weighted (DW) imaging schemes with regard to apparent diffusion coefficient (ADC) accuracy, ADC precision, and DW contrast-to-noise ratio (CNR) for different types lesions breast tissue.Institutional review board approval written, informed consent were obtained. Fifty-one patients histopathologic correlation or follow-up performed a 3.0-T MR imager included in this study. There 112 regions interest drawn 24 malignant, 17 benign, 20 cystic, 51...
Abstract Breast density is an independent risk factor for the development of breast cancer and also decreases sensitivity mammography screening. Consequently, women with extremely dense breasts face increased late diagnosis cancer. These are, therefore, underserved current mammographic screening programs. The results recent studies reporting on contrast-enhanced MRI as a method in provide compelling evidence that this approach can enable important reduction mortality these cost-effective....
Purpose The aim of this study was to assess the potential machine learning with multiparametric magnetic resonance imaging (mpMRI) for early prediction pathological complete response (pCR) neoadjuvant chemotherapy (NAC) and survival outcomes in breast cancer patients. Materials Methods This institutional review board–approved prospective included 38 women (median age, 46.5 years; range, 25–70 years) who were scheduled NAC underwent mpMRI at 3 T dynamic contrast-enhanced (DCE),...
To study the feasibility of automatically identifying normal digital mammography (DM) exams with artificial intelligence (AI) to reduce breast cancer screening reading workload.A total 2652 DM (653 cancer) and interpretations by 101 radiologists were gathered from nine previously performed multi-reader multi-case receiver operating characteristic (MRMC ROC) studies. An AI system was used obtain a score between 1 10 for each exam, representing likelihood present. Using all scores 9 as...
We summarise here the information to be provided women and referring physicians about percutaneous breast biopsy lesion localisation under imaging guidance. After explaining why a preoperative diagnosis with is preferred surgical biopsy, we illustrate criteria used by radiologists for choosing most appropriate combination of device type sampling technique Then, describe commonly devices, from fine-needle tissue larger needles, namely core needle vacuum-assisted how mammography, digital...
To measure the effect of biopsy device, probe size, mammographic lesion type, and number samples obtained per on ductal carcinoma in situ (DCIS) underestimation rate.Nonpalpable breast lesions at 16 institutions received a histologic diagnosis DCIS after 14-gauge automated large-core 373 14- or 11-gauge directional vacuum-assisted 953 lesions. The presence histopathologic invasive was noted subsequent surgical biopsy.By performing chi(2) test, independent significant rates by device were...
To prospectively compare the sensitivity and specificity of high-spatial-resolution dynamic contrast material-enhanced magnetic resonance (MR) imaging with those T2-weighted MR imaging, performed an endorectal coil (ERC), for assessment extracapsular extension (ECE) staging in patients prostate cancer, histopathologic findings as reference.The study was approved by institutional internal review board; a signed informed consent obtained. at 1.5 T combined surface coils ERCs 32 (mean age, 65...
Dynamic High-Spatial-Resolution MR Imaging of Suspicious Breast LesionsDiagnostic Criteria and Interobserver VariabilityKaren Kinkel1 2, Thomas H. Helbich1 3, Laura J. Esserman4, John Barclay5, Ellen Schwerin1, Edward A. Sickles1 Nola M. Hylton1Audio Available | Share
PURPOSE: To compare a computed tomographic (CT)-based scoring system with nonimaging indexes of pulmonary status in patients cystic fibrosis. MATERIALS AND METHODS: Pulmonary CT findings were assessed 117 fibrosis, cases classified according to three groups by age; 0–5 years, 6–16 and 17 years older. Images examined for specific abnormalities, the severity anatomic extent each sign used generate score. Scores category global score patient correlated function test results, clinical status,...
Purpose To qualitatively and quantitatively compare the diagnostic value of diffusion-weighted (DW) magnetic resonance (MR) imaging based on standard single-shot echo-planar readout-segmented in patients with breast cancer at 3.0 T. Materials Methods Institutional review board approval written informed consent were obtained. Forty-seven 49 histopathologically verified lesions included this study. In all patients, DW imaging, comparable parameters, was performed a 3.0-T MR imager. Two...
EUSOBI and 30 national breast radiology bodies support mammography for population-based screening, demonstrated to reduce cancer (BC) mortality treatment impact. According the International Agency Research on Cancer, reduction in is 40 % women aged 50–69 years taking up invitation while probability of false-positive needle biopsy <1 per round overdiagnosis only 1–10 a 20-year screening. Mortality was also observed age groups 40–49 70–74 years, although with “limited evidence”. Thus, we...
To retrospectively determine the false-negative rate and underestimation of ultrasonography (US)-guided 14-gauge core-needle breast biopsy (CNB) in nonpalpable lesions, with validation at surgical excision histologic examination stability during clinical imaging follow-up.Informed consent was waived by institutional review board for this retrospective 1352 cases. In 1061 cases, patients underwent lesions visible US subsequent to US-guided CNB. Follow-up another 291 benign CNB showed...
This article summarises the information that should be provided to women and referring physicians about breast ultrasound (US). After explaining physical principles, technical procedure safety of US, is given its ability make a correct diagnosis, depending on setting in which it applied. The following definite indications for US female subjects are proposed: palpable lump; axillary adenopathy; first diagnostic approach clinical abnormalities under 40 pregnant or lactating women; suspicious...
Purpose: To retrospectively determine whether nonpalpable solid breast masses that were partially or completely obscured at mammography and diagnosed as probably benign only ultrasonography (US) can be safely managed with follow-up. Materials Methods: The local ethics committee approved this study; informed consent was not required. In 409 women, 448 identified classified US; these either by dense fibroglandular tissue. Of the masses, 445 followed up, while biopsy performed after initial...
The aims of this study were to compare dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) with diffusion-weighted (DWI) apparent diffusion coefficient mapping as a stand-alone parameter without any other supportive sequence for breast cancer detection and assess its combination multiparametric MRI (mpMRI) the breast.In institutional review board-approved single-center study, prospectively acquired data 106 patients who underwent from 12/2010 09/2014 an abnormality (Breast...
Primary staging of prostate cancer relies on modalities, which are limited. We evaluate simultaneous [68Ga]Ga-PSMA-11 PET (PSMA-PET)/MRI as a new diagnostic method for primary tumor-node-metastasis compared with histology and its impact therapeutic decisions.We investigated 122 patients PSMA-PET/MRI prior to planned radical prostatectomy (RP). endpoint was the accuracy in tumor staging-relevant histology. In addition, multidisciplinary team reassessed initial approach management.PSMA-PET/MRI...
The purpose of this study was to compare the diagnostic accuracy dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) as a single parameter multiparametric (MP) MRI with 2 (DCE and diffusion-weighted [DWI]) 3 MRI, DWI, 3-dimensional proton spectroscopic [3D H-MRSI]) parameters in breast cancer diagnosis.This prospective approved by institutional review board. Written informed consent obtained all patients. One hundred thirteen female patients (mean age, 52 years; range, 22-86...