A5101923111- Foot and Ankle Surgery
- Lower Extremity Biomechanics and Pathologies
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Diabetic Foot Ulcer Assessment and Management
- Tendon Structure and Treatment
- Prosthetics and Rehabilitation Robotics
- Muscle activation and electromyography studies
- Medical Imaging and Analysis
- Effects of Vibration on Health
- Balance, Gait, and Falls Prevention
- Spinal Cord Injury Research
- Winter Sports Injuries and Performance
- Plant Pathogens and Fungal Diseases
- Wound Healing and Treatments
- Gait Recognition and Analysis
- Healthcare and Venom Research
- Reconstructive Surgery and Microvascular Techniques
- Synthesis of Organic Compounds
- Microbial Metabolic Engineering and Bioproduction
- Hand Gesture Recognition Systems
- Orthopaedic implants and arthroplasty
- Orthopedic Surgery and Rehabilitation
- Neurological Disease Mechanisms and Treatments
- Enzyme Catalysis and Immobilization
University of Calgary
2023-2025
Zhejiang University
2004-2025
Tsinghua University
2024
Chinese Academy of Social Sciences
2024
Institute of Archaeology
2024
University of Alberta
2017-2024
Aero Engine Corporation of China (China)
2022-2023
Brown University
2013-2023
University of Pennsylvania
2023
Northwestern Polytechnical University
2023
Ginsenosides are the primary bioactive components of ginseng, which is a popular medicinal plant that exhibits diverse pharmacological activities. Protopanaxadiol, protopanaxatriol and oleanolic acid three basic aglycons ginsenosides. Producing ginsenosides in Saccharomyces cerevisiae was realized this work provides an alternative route compared to traditional extraction methods. Synthetic pathways these were constructed S. by introducing β-amyrin synthase, dammarenediol-II protopanaxadiol...
China prioritizes a coordinated and sustainable shift from rural to urban areas, termed rural-urban transformation. This involves land, population, industry urbanization. Here we explore the spatiotemporal dynamics of transformation patterns in China, focusing on degree integrated coupling between three tracks. To conduct our investigation, utilized urbanization cube theory, satellite-derived gridded datasets, self-organizing map. Our findings show that eastern has higher levels compared...
Synergy is now a widely recognized approach that has direct applicability for new pharmaceuticals. The ethanolic extract of the aerial parts herb Sophora moorcroftiana showed significant antibacterial activity against drug‐resistant Staphylococcus aureus , and its minimum inhibitory concentration (MIC) was 8 µg/mL. In phytochemical study extract, five flavonoids were obtained. However, isolates exhibited in range 32–128 µg/mL, which weaker than extract. combination with antibiotics,...
Although stents have great success of treating cardiovascular disease, it actually undermined by the in-stent restenosis and their long-term fatigue failure. The geometry stent affects its service performance ultimately life. Besides, improper length balloon leads to transient mechanical injury vessel wall restenosis. Conventional optimization method dilatation comparing several designs choosing best one as optimal design cannot find global in space. In this study, an adaptive based on...
Purpose The present study is to explore the appropriate plantar support force for its effect on improving collapse of medial longitudinal arch with flexible flatfoot. Methods A finite element model fascia attenuation was constructed simulating as evaluated. equivalent stress articular surface joints in and maximum principal ligaments around ankle were obtained. Results height fall smaller when applying 15% body-weight-bearing compared 10% while 20% over support. each joint smallest or force....
The marine bacterium, Vibrio natriegens, grows quickly in a environment and can significantly accelerate the corrosion of steel materials. Here, we present an approach to inhibit natriegens-induced by biomineralization. is mitigated seawater via formation biomineralization induced Bacillus subtilis. film composed extracellular polymeric substances calcite, exhibiting stable anti-corrosion activity. microbial diversity medium chemistry tests demonstrated that inhibition V. natriegens growth...
The intra-abdominal pressure (IAP), which generates extensor torque and unloads the spine, is often neglected in most of numerical studies that use musculoskeletal (MSK) or finite element (FE) spine models. Hence, spinal loads predicted by these models may not be realistic. In this work, we quantified effects IAP variation forward flexion on load-sharing using a novel computational tool combines MSK model trunk with FE ligamentous lumbosacral spine. muscle reaction forces at T12-L1 junction,...
Abstract Seven new sesquiterpenoids together with 21 known sesquiterpenoid derivatives were isolated from the medicinal plant Ferula ferulioides ( Steud .) Korovin . Their structures elucidated by comprehensive spectroscopic analyses and chemical transformations. The compounds evaluated for their antibacterial activities against a panel of bacteria including multidrug‐resistant (MDR) methicillin‐resistant Staphylococcus aureus (MRSA), displaying minimum inhibitory concentration MIC ) values...
Large skin defects are commonly observed in the clinic and have attracted much attention recently. Therefore, finding an effective solution for large is a global problem. The objective of present study was to assess effectiveness EASApprox® skin-stretching system closing defects. Skin (5×5 cm) were created on forearms 9 Bama miniature pigs, which randomly divided into following three groups: Direct suture, new device Kirschner wires. Microcirculation assessed before surgery after wound...
Preeclampsia (PE) is a multisystem disorder unique to Homo sapiens that known cause maternal and perinatal mortality morbidity. Between 5–7% of all pregnancies are affected by PE it responsible for approximately 50,000 deaths annually. The pathogenesis remains poorly understood. However, the results this study indicated insufficient decidualization plays significant role. NR5A1 NR5A2 orphan members Ftz-F1 subfamily nuclear receptors involved in mammal follicular development, female...
Due to the complexity of articular interconnections and tenuous blood supply talus, talus fractures are often associated with complications (e.g., avascular necrosis). Currently, surgically fusing adjacent bones is widely used as treatment fractures, but this procedure can greatly reduce mobility in ankle hindfoot. Alternatively, customized implants have shown an overall satisfactory patient feedback limitation high expenses time-consuming manufacturing process. In order circumvent these...
Cell division protein, FtsZ, has been identified as a new potential antimicrobial target against multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus (MRSA). By using computer-aided simulation, the phenolic compounds magnolol honokiol from Magnolia officinalis were shown to have high anchor energies FtsZ of S. aureus. The calculated binding for this (PDB Code: 4DXD) established be -7.6 kcal/mol -8.2 kcal/mol, respectively. Both them showed polymerization inhibition...
Acute generalized exanthematous pustulosis is a severe, usually drug-related reaction, characterized by an acute onset of mainly small non-follicular pustules on erythematous base. Most cases (AGEP) clear quickly with systemic corticosteroid, but severe or recalcitrant may need other therapies. In this case, man in his 40 s history psoriasis consulted physician about widespread erythema, pustules, target lesions, and fever after the administration quadruple antituberculosis drug. Routine...