A5101885661- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Ferroptosis and cancer prognosis
- Piperaceae Chemical and Biological Studies
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Mass Spectrometry Techniques and Applications
- Yersinia bacterium, plague, ectoparasites research
- Bacteriophages and microbial interactions
- Bacillus and Francisella bacterial research
- Immune Response and Inflammation
- DNA and Nucleic Acid Chemistry
- Antifungal resistance and susceptibility
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Respiratory viral infections research
- Influenza Virus Research Studies
- Pharmacogenetics and Drug Metabolism
- Zoonotic diseases and public health
- Metabolomics and Mass Spectrometry Studies
- RNA modifications and cancer
- Berberine and alkaloids research
Southern University of Science and Technology
2021-2024
Institute of Microbiology
2019
Jinan Military General Hospital
2017
Second Military Medical University
2007
Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C. in vitro BBR had major antifungal effect synergism, while FLC played role increasing intracellular concentration. Since activity alone very weak (MIC > 128 μg/mL), it was assumed naturally tolerant to BBR, this tolerance could be reversed by FLC. The present aimed elucidate mechanism...
Breast cancer has overtaken lung to rank as the top malignant tumor in terms of incidence. Herein, a gold nanostar (denoted AuNS) is used for loading disulfide-coupled camptothecin-fluorophore prodrugs CPT-SS-FL) form nanocomposite AuNS@CPT-SS-FL AS), which, turn, further encapsulated with hyaluronic acid (HA) give final nanoplatform AuNS@CPT-SS-FL@HA ASH). ASH effectively carries prodrug and targets CD44 receptor on surface cells. The endogenously overexpressed glutathione (GSH) cells...
Background. The majority of lung cancers are adenocarcinomas, with the proportion being 40%. patients mostly diagnosed in middle and late stages metastasis easy recurrence, which poses great challenge to treatment prognosis. Platinum-based chemotherapy is a primary for adenocarcinoma, frequently causes drug resistance. As result, it important uncover mechanisms chemoresponse adenocarcinoma platinum-based chemotherapy. Methods. genes from dataset GSE7880 were gathered into gene modules...
The nasal-associated lymphoid tissues (NALTs), embedded in the submucosa of murine upper respiratory tract, represents an important site induction for local mucosal immune responses to airborne pathogens and intranasal vaccines. Here, we systematically investigated humoral cellular NALTs mice infected with A/Beijing/501/2009 (BJ501) A/Puerto Rico/8/1934 (PR8) viruses. Compared PR8 infection, BJ501 induced a more rapid increase virus-specific IgA IgG antibodies nasal lavage fluid higher ratio...