A5048610221- COVID-19 epidemiological studies
- Mental Health Treatment and Access
- SARS-CoV-2 and COVID-19 Research
- Health disparities and outcomes
- Vaccine Coverage and Hesitancy
- Homelessness and Social Issues
- Lymphoma Diagnosis and Treatment
- Emergency and Acute Care Studies
- Psychiatric care and mental health services
- COVID-19 and Mental Health
- Global Cancer Incidence and Screening
- Digital Mental Health Interventions
- Viral Infections and Outbreaks Research
- Telemedicine and Telehealth Implementation
- Schizophrenia research and treatment
- Cancer, Lipids, and Metabolism
- Healthcare Decision-Making and Restraints
- Health Policy Implementation Science
- Adolescent and Pediatric Healthcare
- Child and Adolescent Psychosocial and Emotional Development
- Food Security and Health in Diverse Populations
- Acute Lymphoblastic Leukemia research
- Multiple and Secondary Primary Cancers
- Healthcare Policy and Management
- Smoking Behavior and Cessation
University of Toronto
2017-2025
Institute for Clinical Evaluative Sciences
2017-2023
Institute of Health Services and Policy Research
2023
Toronto Public Health
2020-2022
Public Health Agency of Canada
2022
University Health Network
2020-2022
Shanxi University
2022
Centre for Addiction and Mental Health
2017-2020
International Council for the Exploration of the Sea
2020
3M (United States)
2017
We examined mortality time trends and premature among individuals with without schizophrenia over a 20-year period.
Mental illness is a leading cause of disability among youth. In Ontario, Canada, rates mental health or addiction–related emergency department (ED) visits continue to rise in children and youth; however, it unclear what driving this change. We deconstructed trend by sociodemographic clinical characteristics, using linked administrative data sets. ED visit increased 89.1 percent between 2006 2017, with the greatest observed for those ages 14–21, high-acuity cases, anxiety mood disorders....
<h3>BACKGROUND:</h3> Little is known about the risk of death among people who visit emergency departments frequently for alcohol-related reasons, including whether mortality increases with increasing frequency visits. Our primary objective was to describe sociodemographic and clinical characteristics this high-risk population examine their 1-year overall mortality, premature cause as a function department in Ontario, Canada. <h3>METHODS:</h3> We conducted population-based retrospective...
Preclinical data suggests anti-lymphoma potential for statins, metformin and cyclooxygenase-2 (COX-2) inhibitors. We performed a retrospective population-based study of all adults aged ≥66 years diagnosed with diffuse large B-cell lymphoma (DLBCL) or transformed treated rituximab containing regimen, between 2005 2015 in Ontario, Canada. Using administrative databases, we assessed the impact medication exposures, prior to chemo-immunotherapy, on survival. Cox regression analyses, controlling...
Operating schools safely during the COVID-19 pandemic requires a balance between health risks and need for in-person learning. Using demographic epidemiological data 31 July 23 November 2020 from Toronto, Canada, we developed compartmental transmission model with age, household setting structure to study impact of reopening in September 2020. The simulates home, community schools, accounting differences infectiousness adults children, work-from-home virtual While found slight increase...
Initial efforts to mitigate the COVID-19 pandemic have relied heavily on non-pharmaceutical interventions (NPIs), including physical distancing, hand hygiene, and mask-wearing. However, an effective vaccine is essential containing spread of virus. We developed a compartmental model examine different strategies for controlling COVID-19. Our framework accounts testing rates, test-turnaround times, vaccination waning immunity. Using reported case data from city Toronto, Canada between Mar-Dec,...
Objective: We sought to determine the utility of health administrative databases for population-based suicide surveillance, as these data are generally more accessible and integrated with other sources compared coroners’ records. Method: In this retrospective validation study, we identified all coroner-confirmed suicides between 2003 2012 in Ontario residents aged 21 over linked information Statistics Canada’s vital statistics set. examined overlap underlying cause death field secondary...
Since December 2020, public health agencies have implemented a variety of vaccination strategies to curb the spread SARS-CoV-2, along with pre-existing Nonpharmaceutical Interventions (NPIs). Initial focused on vaccinating elderly prevent hospitalizations and deaths, but vaccines becoming available broader population, it became important determine optimal strategy enable safe lifting NPIs while avoiding virus resurgence.
Objective: Although evidence suggests that treatment seeking for mental illness has increased over time, little is known about how the health system meeting increasing demand services. We examined trends in physician-based service use across multiple sectors. Method: In this population-based study, we used linked health-administrative databases to measure annual rates of health–related outpatient physician visits family physicians and psychiatrists, emergency department visits,...
Lung cancer is the most common and cause of death in Canada, with approximately 50% cases diagnosed at stage IV. Sociodemographic inequalities lung diagnosis have been documented, but it not known if exist respect to immigration status. We used multiple linked health-administrative databases create a cohort Ontarians 40–105 years age who were an incident between 1 April 2012 31 March 2017. modified Poisson regression robust standard errors examine risk late vs. early among immigrants...
Background Since 2005, the Smoking Treatment for Ontario Patients (STOP) program has provided smoking cessation treatment of varying form and intensity to smokers through 11 distinct models, either in-person at partnering healthcare organizations or remotely via web telephone. We aimed characterize patient populations reached by different models. Methods linked self-report data health administrative databases describe sociodemographics, physical mental comorbidity, utilization costs. Our...
<h3>Background:</h3> Globally, nonpharmaceutical interventions for COVID-19, including stay-at-home policies, limitations on gatherings and closure of public spaces, are being lifted. We explored the effect lifting a policy virus resurgence under different conditions. <h3>Methods:</h3> Using confirmed case data from Toronto, Canada, between Feb. 24 June 24, 2020, we ran compartmental model with household structure to simulate impact considering levels compliance. estimated threshold values...
Objective: Small clinical samples suggest that psychiatric inpatients report a lifetime history of interpersonal trauma. Since past experiences trauma may complicate prognosis and treatment trajectories, population-level knowledge is needed about its prevalence correlates among inpatients. Methods: Using health-administrative databases comprising all adult in Ontario, Canada (2009 to 2016, n = 160,436, 49% women), we identified those who reported experiencing physical, sexual, and/or...
Summary Background In many parts of the world, restrictive non-pharmaceutical interventions (NPI) that aim to reduce contact rates, including stay-at-home orders, limitations on gatherings, and closure public places, are being lifted, with possibility epidemic resurges if alternative measures not strong enough. Here we capture combination use NPI’s reopening which will prevent an infection rebound. Methods We employ SEAIR model household structure able policy (SAHP). To reflect changes in...
Abstract Efforts to mitigate the COVID-19 pandemic have relied heavily on non-pharmaceutical interventions ( NPIs ), including physical distancing, hand hygiene, and mask-wearing. However, an effective vaccine is essential containing spread of virus. The first doses were distributed at end 2020, but efficacy, period immunity it will provide, percentage coverage still remain unclear. We developed a compartment model examine different strategies for controlling COVID-19. Our framework accounts...
The promise of e-mental health (e-MH) services in meeting growing service demands and for overcoming access barriers to mental healthcare is the focus this paper. While policy window e-MH appears be open due COVID-19 pandemic, issues relating financing, organization delivery Canadian MH must considered.
BackgroundThe linkage of records across administrative databases has become a powerful tool to increase information available undertake research and analytics in privacy protective manner. ObjectiveThe objective this paper was describe the data integration strategy used link Ontario Ministry Children, Community Social Services (MCCSS)-Social Assistance (SA) database with health care data. MethodsDeterministic probabilistic methods were MCCSS-SA (2003-2016) Registered Persons Database,...
<h3>Importance</h3> Surgeon-directed knowledge translation (KT) interventions for rectal cancer surgery are designed to improve patient measures, such as rates of permanent colostomy and in-hospital mortality, survival. <h3>Objective</h3> To evaluate the association sustained, iterative, integrated KT directed at all surgeons with process outcome measures among patients undergoing in a geographic region. <h3>Design, Setting, Participants</h3> This quality improvement study used...
Abstract Background Colorectal cancer (CRC) is the second most common cause of death in Canada. Immigrants Ontario, Canada’s populous province, are known to have lower rates CRC screening, but differences stage diagnosis not known. Methods We utilized linked administrative databases compare early (stage I–II) versus late III–IV) for immigrants long-term residents among patients diagnosed Ontario between 2012 and 2017 ( n = 37,717) examined association immigration-related, sociodemographic,...
Objective We sought to examine the short-term and long-term impacts of psychiatric hospitalisations among patients Chinese South Asian origin. Design Retrospective population-based cohort study using linked health administrative data. Setting examined all adult inpatients discharged between 1 April 2006 31 March 2014 in Ontario, Canada, who were classified as Chinese, other ethnicities (ie, ‘general population’) a validated algorithm. identified 2552 2439 127 142 general population patients....
Background: Because of prolonged screening requirements, patient and time-dependent selection have been proposed as potential biases in clinical trials. The process may exclude patients with a need for emergent treatment (and short period from diagnosis to initiation [DTI]). We explored the impact DTI on overall survival (OS) population-based cohort diffuse large B-cell lymphoma (DLBCL). Patients Methods: Using administrative databases Ontario, Canada, we identified adults aged ≥18 years...