A5028554678- Influenza Virus Research Studies
- Respiratory viral infections research
- Vaccine Coverage and Hesitancy
- Animal Disease Management and Epidemiology
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
- Viral Infections and Vectors
- Smoking Behavior and Cessation
- Virus-based gene therapy research
- SARS-CoV-2 and COVID-19 Research
- Travel-related health issues
- Congenital Anomalies and Fetal Surgery
- Viral Infections and Outbreaks Research
- COVID-19 Pandemic Impacts
- Child Nutrition and Water Access
- Data-Driven Disease Surveillance
- Infection Control and Ventilation
- Hepatitis Viruses Studies and Epidemiology
- Viral Infections and Immunology Research
- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- Child and Adolescent Health
- Neonatal Respiratory Health Research
- Fire effects on ecosystems
United States Naval Medical Research Unit SOUTH
2015-2025
National University of San Marcos
2007-2023
Johns Hopkins University
2009-2017
Centers for Disease Control and Prevention
2009-2015
The University of Sydney
2015
National Institutes of Health
2015
Arizona State University
2015
J. Craig Venter Institute
2015
University of California, San Francisco
2015
Tulane University
2015
Latin America has a substantial burden of influenza and rising Internet access could benefit from real-time epidemic prediction web tools such as Google Flu Trends (GFT) to assist in risk communication resource allocation during epidemics. However, there never been published assessment GFT's accuracy most American countries or any low- middle-income country. Our aim was evaluate GFT Argentina, Bolivia, Brazil, Chile, Mexico, Paraguay, Peru, Uruguay. Weekly influenza-test positive proportions...
Taeniasis due to Taenia solium is a disease with important public health consequences, since the larval stage not exclusive animal intermediate, pig, but also infects humans, causing neurocysticercosis. Early diagnosis and treatment of T. tapeworm carriers prevent human cysticercosis. Current based on microscopic observation eggs lacks both sensitivity specificity. In present study, nested-PCR assay targeting Tso31 gene was developed for specific taeniasis solium. Initial specificity testing...
We identified highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b in wild birds, poultry, and a lion Peru during November 2022-February 2023 markers associated with transmission adaptation antiviral drug resistance. Continuous genomic surveillance is needed to inform public health measures avoid mass animal deaths.
Norovirus is the leading cause of acute gastroenteritis (AGE) globally. Few longitudinal studies have assessed norovirus-associated AGE incidence across age groups in community settings Latin America. During April 2015–April 2019, active surveillance for among members all ages was conducted through household visits two to three times per week San Jeronimo, Cusco, Peru. An asymptomatic control selected every fifth case. Stool specimens were collected from cases, members, and they tested...
Abstract To determine genotypes of avian influenza virus circulating among wild birds in South America, we collected and tested environmental fecal samples from along the coast Peru, June 2006–December 2007. The 9 isolates recovered represented 4 low-pathogenicity strains: subtypes H3N8, H4N5, H10N9, H13N2.
There are limited data on the burden of disease posed by influenza in low- and middle-income countries. Furthermore, most estimates worldwide rely passive sentinel surveillance at health clinics hospitals that lack accurate population denominators. We documented incidence, seasonality, health-system utilization with illness, vaccination coverage through active community-based 4 ecologically distinct regions Peru over 6 years. Approximately 7200 people 1500 randomly selected households were...
Despite a government-subsidized vaccination program, healthcare personnel (HCP) influenza uptake remains low in Peru. Using three years of cross-sectional surveys and an additional five prior history HCP Peru, we explored knowledge, attitudes, practices (KAP) illness its impact on frequency.In 2016, the Estudio Vacuna de Influenza Peru (VIP) cohort was initiated Lima, which collected information about KAP from 2011─2018. were classified by their 8-year as never (0 years), infrequently (1─4...
Disease surveillance, essential for guid -ing the public health response to influ-enza and other respiratory diseases, al-lows early case detection implementation of preventive measures. The World Health Organization (WHO) recommends passive health-provider based or “sentinel surveil -lance”, influenza-like illness (ILI)
It remains unclear whether lineages of influenza A(H3N2) virus can persist in the tropics and seed temperate areas. We used viral gene sequence data sampled from Peru to test this source-sink model for a Latin American country. Viruses were obtained during 2010-2012 surveillance cohorts Cusco, Tumbes, Puerto Maldonado, Lima. Specimens positive randomly selected underwent hemagglutinin sequencing phylogeographic analyses. Analysis 389 sequences 2,192 global demonstrated interseasonal...
Although Peru provides safe and effective influenza vaccines free-of-charge, coverage among vaccine target groups like pregnant women older adults remains low. To improve risk communication messages uptake, we explored knowledge, perceptions practices about illness vaccination.A cross-sectional, community-based survey with a three-stage cluster sampling design was conducted in three cities Peru. We included mothers of young children, persons ≥65 years. Participants completed questionnaire...
Estimating the burden of disease averted by vaccination can assist policymakers to implement, adjust, and communicate value programs. Demonstrating use a newly available modeling tool, we estimated influenza illnesses seasonal in El Salvador, Panama, Peru during 2011–2017 among two vaccine target populations: children aged 6–23 months pregnant women. We derived model inputs, including incidence, coverage, effectiveness, multipliers from publicly country-level surveillance data cohort...
We aimed to determine the frequency of pH1N1 transmission between humans and swine on backyard farms in Tumbes, Peru.Two-year serial cross-sectional study comprising four sampling periods: March 2009 (pre-pandemic), October (peak pandemic Peru), April 2010 (1st post-pandemic period), 2011 (2nd period).Backyard serum, tracheal swabs, lung sample were collected during each period.We assessed current past infection through serological testing, virus culture, RT-PCR compared results with human...
We present findings describing the epidemiology of non-severe acute respiratory syndrome human coronavirus-associated influenza-like illness from a population-based active follow-up study in four different regions Peru. In 2010, prevalence infections by coronaviruses 229E, OC43, NL63, or HKU1 was 6.4% participants with who tested negative for influenza viruses. Ten 11 coronavirus were identified fall–winter season. Human are Peru and relatively frequently associated
Data on norovirus epidemiology among all ages in community settings are scarce, especially from tropical settings.We implemented active surveillance 297 households Peru October 2012 to August 2015 assess the burden of diarrhea and acute gastroenteritis (AGE) due a lower-middle-income community. During period 1 (October 2012-May 2013), we used "traditional" case definition (≥3 loose/liquid stools within 24 hours). 2 (June 2013-August 2015), an expanded AGE (by adding ≥2 vomiting episodes...
Introduction Influenza disease burden and economic impact data are needed to assess the potential value of interventions. Such information is limited from resource‐limited settings. We therefore studied cost influenza in Peru. Methods used collected during June 2009–December 2010 laboratory‐confirmed cases identified through a household cohort determined self‐reported direct indirect costs self‐treatment, outpatient care, emergency ward hospitalizations standardized questionnaires. recorded...
Introduction: We evaluated knowledge, attitudes, and practices (KAP) related to influenza vaccination among pregnant women in three selected countries.Methods: During 2017, seeking antenatal care at hospitals participating sites were enrolled. described characteristics responses KAP questions. also predictors associated with during pregnancy substantial vaccine uptake by multivariable logistic regression.Results: Overall, 4,648 completed the survey. There differences survey populations; only...
Uncertainty about risk of illness and the value influenza vaccines negatively affects vaccine uptake among persons targeted for vaccination.
The World Health Organization identifies pregnant women as at high-risk for severe influenza, but influenza vaccines are underutilized among women. Data on burden during pregnancy largely limited to high-income countries and data the impact of birth perinatal outcomes scarce. This prospective, longitudinal cohort study in middle-income is designed address three primary objectives: 1) evaluate effect laboratory-confirmed outcomes; 2) estimate incidences all-cause acute respiratory illness...
We investigated hantaviruses in rodents the southern Amazon Basin of Peru and identified an Andes virus variant from Neacomys spinosus mice. This finding extends known range this South America recognized Peru. Further studies epizoology region are warranted.
While costs of norovirus acute gastroenteritis (AGE) to healthcare systems have been estimated, out-of-pocket and indirect incurred by households are not well documented in community settings, particularly developing countries. We conducted active surveillance for AGE two communities Peru: Puerto Maldonado (October 2012–August 2015) San Jeronimo (April 2015–April 2019). Norovirus events with PCR-positive stool specimens were included. Data collected follow-up interviews included...
The Estudio Vacuna de Influenza Peru (VIP) cohort aims to describe the frequency of influenza virus infection, identify predictors vaccine acceptance, examine effects repeated vaccination on immunogenicity, and evaluate effectiveness among HCP.The VIP prospectively followed HCP in Lima, Peru, during 2016-2018 seasons; a fourth year is ongoing. Participants contribute blood samples before after season (for vaccinees). Weekly surveillance conducted acute respiratory or febrile illnesses...