- Biosensors and Analytical Detection
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Molecular Sensors and Ion Detection
- Magnetic properties of thin films
- Sulfur Compounds in Biology
- Carbon and Quantum Dots Applications
- SARS-CoV-2 detection and testing
- Advanced Nanomaterials in Catalysis
- Analytical chemistry methods development
- Nanocluster Synthesis and Applications
- Luminescence and Fluorescent Materials
- Advanced Biosensing Techniques and Applications
- Lanthanide and Transition Metal Complexes
- Magnetism in coordination complexes
- Mercury impact and mitigation studies
- SARS-CoV-2 and COVID-19 Research
- Covalent Organic Framework Applications
- HIV/AIDS drug development and treatment
- Melamine detection and toxicity
- Radioactive element chemistry and processing
- Color Science and Applications
- Magnetic and transport properties of perovskites and related materials
- Multiferroics and related materials
- Analytical Chemistry and Sensors
Zhejiang University of Technology
2016-2025
Jilin University of Chemical Technology
2024-2025
Institute of Chemical Technology
2025
Shanghai Jiao Tong University
2025
Ruijin Hospital
2016-2025
Guilin University of Technology
2024
Northwest A&F University
2018-2024
Shandong Provincial Hospital
2023-2024
Shandong First Medical University
2023-2024
Shanghai East Hospital
2024
A microporous three-dimensional (3D) hydrogen-bonded organic framework (HOF-20) has been constructed from an aromatic-rich tetratopic carboxylic acid, 5-(2,6-bis(4-carboxyphenyl)pyridin-4-yl)isophthalic acid (H4BCPIA). The activated HOF-20a a moderately high Brunauer–Emmett–Teller (BET) surface area of 1323 m2 g–1 and excellent stability in water HCl aqueous solution. HOF-20 exhibits highly efficient turn-up fluorescent sensing aniline with detection limit 2.24 μM is selective toward the...
A novel Zr-MOF based smart adsorbent was fabricated for the simultaneous detection and removal of organophosphorus pesticides in wastewater.
Lipid droplets (LDs), as dynamic complex organelles, are involved in various physiological processes, and their numbers activity related to many diseases, even cancer. Hence, locating concentration monitoring of LDs very important scientific bioresearch health care. In this work, we prepared two simple luminogens (FAS DPAS) via facile synthetic procedures purification. They feature aggregation-induced emission excited state intramolecular proton transfer characteristics. exhibit large Stokes...
Abstract Creating secondary nanostructures from fundamental building blocks with simultaneous high loading capacity and well‐controlled size/uniformity, is highly desired for nanoscale synergism integration of functional units. Here a novel strategy reported hydrophobic quantum dots (QDs) assembley porous templates, to form pitaya‐type fluorescent silica colloids densely packed intact QDs throughout the matrix. The mercapto‐terminated dendritic spheres accessible central–radial pores...
A site-specific epitaxial-growth strategy is developed to synthesize two types of MOF-on-MOF heterostructures with elaborately designed architectures, which are comprised MOFs totally different compositions.
Antibiotics abuse has caused various problems threatening human health and ecological environment. Monitoring antibiotics residual levels is of great significance, yet still challenging for quantitative point-of-need testing with high-sensitivity visual capability. Here we developed a competitive lateral flow immunoassay (CLFIA) platform flexible readout enrofloxacin (ENR), regularly added antibiotic. To overcome the limitation low sensitivity traditional colloidal gold-based CLFIA,...
Immunological detection of small molecules in a point-of-care (POC) format is great significance yet remains challenging for accurate visual discrimination and quantitative analysis. Here, we report novel hue recognition competitive fluorescent lateral flow immunoassay (HCLFIA) strip that allows both aflatoxin M1 (AFM1). The HCLFIA works on the basis ratiometric change emission, arising from overlap fluorescence signals two nanocomposites tagged with probe antibodies coated antigens. A...
Abstract The hue‐recognition based point‐of‐care diagnosis favorites both human visual perception and imaging analysis with portable terminals. Semiconductor nanoplatelets (NPLs) as an emerging narrow‐emissive fluorophore particularly suit above color‐purity desired diagnosis, but are hindered by their intrinsic hydrophobicity difficulty in controlled assembly. Here the host‐guest assembling of hydrophobic NPLs developed within 3D porous space dendritic templates, stepwise surface...
The micellization of poly(ethylene oxide)−poly(propylene oxide)−poly(ethylene oxide) (PEO−PPO−PEO) block copolymer in aqueous solution the absence and presence salts was studied by Fourier transform infrared (FTIR) spectroscopy. temperature-dependent changes C−O−C stretching vibration band were used to denote critical temperatures (CMT). CMT Pluronic F127 modified significantly addition as previously shown. proportion anhydrous methyl groups increased, while hydrated decreased during...
Lateral flow immunoassay (LFIA), as a prominent point-of-care (POC) test platform, has been extensively adopted for rapid, on-site, and facile diagnosis of pathogen infections disease biomarkers. Exploring novel structured optical labels LFIA with amplified signal complementary detection modes favors the sensitive flexible POC diagnosis. Here, bimodal both colorimetric fluorescent readout were fabricated via layered sequential assembly strategy based on affinity templates hydrophobic...
Cold stress restricts peanut (Arachis hypogaea L.) growth, development, and yield. However, the specific mechanism of cold tolerance in remains unknown. Here, comparative physiological, transcriptomic, lipidomic analyses tolerant variety NH5 sensitive FH18 at different time points were conducted to fill this gap. Transcriptomic analysis revealed lipid metabolism including membrane fatty acid may be a significant contributor tolerance, 59 cold-tolerant genes involved identified. Lipidomic...
Exploring signal amplification strategies to enhance the sensitivity of lateral flow immunoassay (LFIA) is great significance for point-of-care (POC) testing low-concentrated targets in field vitro diagnostics. Here, a highly-sensitive LFIA platform using compact and hierarchical magneto-fluorescent assemblies as both target-enrichment substrates optical sensing labels demonstrated. The large-pored dendritic templates are utilized high-density incorporation superparamagnetic iron oxide...
Although the competitive lateral flow immunoassay (CLFIA) using gold nanoparticles (AuNPs) as labels has been widely adopted for rapid detection of small molecules, its sensitivity is often constrained by insufficient colorimetric signal produced conventional AuNPs labels. Herein, we introduce a new type intensified label, denoted SAAS, which engineered integrating gold-silver alloy (Au-Ag NPs) within dendritic silica scaffold. These pitaya-type nanohybrids combine advantages amplified molar...
Paper-based lateral flow immunoassays (LFIAs) are cost-effective, portable, and simple methods for detection of diverse analytes, which however only provide qualitative or semiquantitative results lack sufficient sensitivity. A combination LFIA electrochemical detection, namely, immunoassay (eLFIA), enables quantitative analytes with high sensitivity, but the integration external electrodes makes system relatively expensive unstable. Herein, working, counter, reference were prepared directly...
Abstract Fluorescent lateral flow immunoassays (FLFIA) is a well‐established rapid detection technique for quantitative analysis. However, achieving accurate analysis of biomarkers at the pg mL −1 level using FLFIA still poses challenges. Herein, an ultrasensitive platform reported utilizing kiwi‐type magneto‐fluorescent silica nanohybrid (designated as MFS) that serves both target‐enrichment substrate and optical signal enhancement label. The spatially‐layered architecture comprises Fe 3 O...