About
Contact & Profiles
A5093205109
Research Areas
- Lysosomal Storage Disorders Research
- Autophagy in Disease and Therapy
- Cellular transport and secretion
University of Gothenburg
2023
Endoplasmic reticulum (ER) proteostasis is maintained by various catabolic pathways. Lysosomes clear entire ER portions ER-phagy, while proteasomes selectively misfolded or surplus aberrant proteins ER-associated degradation (ERAD). Recently, lysosomes have also been implicated in the selective clearance of proteins, but molecular basis remains unclear. Here, we show that phosphatidylinositol-3-phosphate (PI3P)-binding protein TOLLIP promotes lysosomal membrane including an artificial...
10.15252/embj.2023114272
article
EN
cc-by-nc-nd
The EMBO Journal
2023-11-06
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