A5101861640- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Pharmacological Effects of Natural Compounds
- Metabolism and Genetic Disorders
- Ginseng Biological Effects and Applications
- Liver Disease Diagnosis and Treatment
- Natural Antidiabetic Agents Studies
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Studies
- Biological and pharmacological studies of plants
- Stress Responses and Cortisol
- Medical Research and Treatments
- Regional resilience and development
- Flavonoids in Medical Research
- Psychological Well-being and Life Satisfaction
- Kruppel-like factors research
- Nutrition, Genetics, and Disease
- Cholinesterase and Neurodegenerative Diseases
- Neuroscience of respiration and sleep
- Cardiovascular Function and Risk Factors
- Cholesterol and Lipid Metabolism
- Tryptophan and brain disorders
- Computational Drug Discovery Methods
- Medicinal Plant Pharmacodynamics Research
- High Altitude and Hypoxia
Liaoning University of Traditional Chinese Medicine
2021-2022
Beijing University of Chinese Medicine
2011-2019
Sichuan University
2017
West China Hospital of Sichuan University
2017
Centre Jean Perrin
2010
Sun Yat-sen University
2010
Sun Yat-sen University Cancer Center
2010
Depression is a global mental disorder disease and greatly threatened human health stress considered to be one of the important factors that lead depression. In this study, we used newly developed iTRAQ labeling high performance liquid chromatography (HPLC) mass spectrum united analysis technology obtained 2176 accurate proteins. Successively, GO IPA software analyze 98 differentially expressed proteins liver in depression rats due chronic restraint stress, showing map proteomics from...
To investigate a proteomics analysis of liver proteins from rats with spleen-deficiency syndrome (SDS) induced by chronic improper diet consumption and fatigue. This study used proteomic profiling method to identify differentially expressed altered pathways involved in SDS rats. Specifically, we collected samples control group fatigue for 4 weeks. The pooled each were labeled 8-plex isobaric tags relative absolute quantitation reagents. together separated high-pH reverse-phase liquid...
An herbal prescription is usually composed of several medicines. The complex and diverse components bring great challenges to its bioactivity study. To comprehensively analyze the an prescription, a new strategy based on peak‐by‐peak cutting knock‐out chromatography was proposed. In this strategy, active compounds were screened out via from extract, influence compound overall activity extract evaluated by chromatography. Qiliqiangxin capsule 11 medicines for treatment chronic heart failure....
To establish a rat model of type 2 diabetes (T2DM) manifesting the Chinese medicine syndrome pattern both qi and yin deficiency for evaluating efficacy herbal formula (CHF), integrative (IM), pioglitazone (PIO) on T2DM indicators in animal model. The was induced by high-fat diet (HFD) streptozotocin (STZ, 30 mg/kg). CHF (3.4 g/kg), PIO (2.7 mg/kg), IM g + 2.7 mg PIO) were administered to rats once daily 14 days. Related laboratory parameters observed. Diabetic showed unsmooth fur, alopecia,...
涵 [10,11] 等研究, 对于中医证候的认识具有一定的方 法学启示意义.总体上看, 有关研究尚缺乏必要的系 统性和评价性.为此本文提出中医证候内涵研究的 基本思路(图 1).2 型糖尿病(T2DM)是一种严重影响人类健康的 内分泌代谢性疾病, 主要由胰岛素作用受损(胰岛素 抵抗)和胰岛素分泌障碍两方面缺陷导致.但其发病 图 1 基于病证结合的中医证候现代内涵研究的基本思路 机制复杂, 现代医学有关糖尿病发病机制目前有多 种不同认识, 涉及糖代谢、糖脂毒性、神经-内分泌调 节异常、氧化应激、炎症损伤等多种学说 [4,12,13] .有 关 T2DM 病程及其病理发展的研究虽然有过一些报 道 [14~16] , 但由于 2 型糖尿病具有异质性和隐匿性, 其 病程长且持续发展, 临床经诊断的患者不可避免地 会接受包括药物在内的各种疗法的干预, 加上临床 研究的限制, 至今为止人们对该病的发病及其病理 演变规律仍不清楚.糖尿病属于中医"消渴"的范畴, 中医认为本病 多因先天禀赋不足、饮食不节、过食肥甘、劳逸失度、 外感六淫、内伤七情等多种因素, 损伤肺、胃、肾等 多个脏腑,...
In recent years, small cities have experienced rapid development, and the living standards of their residents increasingly approximated those larger urban centers. Due to smaller scale, these inherent advantages in transitioning sustainable development models. The post-pandemic era, characterized by job reductions large economic appeal lower costs, has seen a migration flow from cities. Chinese government traditionally emphasized growth. While policies started incorporate environmental...
Owing to the enhanced accessibility afforded by high-speed rail, relationship between megacities and their neighboring cities has grown closer. Megacities exert a significant influence on land use of cities. This study employs spatial econometric model investigate direct impact spillover effects rail urban values, based panel data from China’s Yangtze River Delta region (2006-2020). The results revealed that shorter commuting times improved frequency service had more substantial effect....
To compare the efficacy of traditional Chinese medicine (TCM), western and integrative in treating type 2 diabetes mellitus (T2DM) a rat model. The T2DM model was established with high-fat diet (HFD) for 35 days single injection streptozotocin (STZ, 30 mg/kg). T2DM-induced rats were divided into three groups, treated Yiqi Yangyin Huatan (YQYYHT) granules (3.84 g/kg per day), pioglitazone (1.35 mg/kg day) or YQYYHT + day+1.35 respectively 14 days. Clinical features behavioral changes, as well...