A5056032547- Helminth infection and control
- Parasite Biology and Host Interactions
- Parasites and Host Interactions
- Coccidia and coccidiosis research
- Antimicrobial Peptides and Activities
- Mollusks and Parasites Studies
- Protein Hydrolysis and Bioactive Peptides
- Research on Leishmaniasis Studies
- Animal Ecology and Behavior Studies
- Marine Sponges and Natural Products
- Biochemical and Structural Characterization
- Aquaculture disease management and microbiota
- Agricultural safety and regulations
- Plant and animal studies
- Invertebrate Immune Response Mechanisms
- Coastal and Marine Management
- Tuberculosis Research and Epidemiology
- Entomological Studies and Ecology
- Reproductive tract infections research
- Reproductive Physiology in Livestock
- Vector-borne infectious diseases
- Insect Utilization and Effects
- Pesticide and Herbicide Environmental Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Trypanosoma species research and implications
Université de Perpignan
2018-2024
Université de Montpellier
2019-2024
Instituto de Medicina Tropical “Pedro Kourí”
2014-2023
Université de Corse Pascal Paoli
2020-2023
Centre National de la Recherche Scientifique
2019-2023
Sciences pour l'Environnement
2023
Ifremer
2019
Instituto de Medicina Tropical
2018
Antimicrobial peptides have been found in mollusks and other sea animals. In this report, a crude extract of the marine snail Cenchritis muricatus was evaluated against human pathogens responsible for multiple deleterious effects diseases. A peptide 1485.26 Da purified by reversed-phase HPLC functionally characterized. This trypsinized sequenced MS/MS technology, sequence (SRSELIVHQR), named Cm-p1 recovered, chemically synthesized demonstrated capacity to prevent development yeasts...
Antimicrobial peptides form part of the first line defense against pathogens for many organisms. Current treatments fungal infections are limited by drug toxicity and pathogen resistance. Cm-p5 (SRSELIVHQRLF), a peptide derived from marine mollusk Cenchritis muricatus Cm-p1, has significantly increased fungistatic activity pathogenic Candida albicans (minimal inhibitory concentration, 10 µg/ml; EC50, 1.146 µg/ml) while exhibiting low toxic effects cultured mammalian cell line. as...
Mollusks have been widely investigated for antimicrobial peptides because their humoral defense against pathogens is mainly based on these small biomolecules. In this report, we describe the identification of three novel from marine mollusk Nerita versicolor. A pool N. versicolor was analyzed with nanoLC-ESI-MS-MS technology, and potential (Nv-p1, Nv-p2 Nv-p3) were identified bioinformatical predictions selected chemical synthesis evaluation biological activity. Database searches showed that...
Fasciolosis is a re-emergent parasitic disease of worldwide significance with major global impact on livestock health and production. In the French Mediterranean island Corsica, fasciolosis has been recognized for long time but little known about its dynamic as main investigations are outdated. Three compartments - definitive domestic hosts, intermediate hosts environment involved in transmission were studied by applying an integrative extensive approach: (1) farm abattoir surveys, (2) snail...
Abstract Fasciolosis is a snail-borne disease, causing serious public and veterinary health problems worldwide. This disease produced by infection with Fasciola hepatica or gigantica through the consumption of vegetables water contaminated parasite's metacercarial cysts. Both species liver flukes are transmitted worldwide small freshwater snails family Lymnaeidae. A global account on that actually may act as potential hosts spp., compiling particular research their geographical distribution...
Antimicrobial peptides (AMPs) are biomolecules with antimicrobial activity against a broad group of pathogens. In the past few decades, AMPs have represented an important alternative for treatment infectious diseases. Their isolation from natural sources has been widely investigated. this sense, mollusks promising organisms identification given that their immune system mainly relies on innate response. report, we characterized peptide fraction Cuban freshwater snail Pomacea poeyana (Pilsbry,...
Recently two peptides isolated from the Cuban freshwater snail Pomacea poeyana (Pilsbry, 1927) were described to have antimicrobial activity against bacterial pathogens. Here we show considerable activities of Pom-1 and Pom-2 reduce viability C. albicans, parapsilosis less common species auris measured as decrease metabolic in resazurin reduction assay for planktonic cells. Although these low, turned out be highly potent inhibitors biofilm formation three Candida tested. Whereas was slightly...
Pseudosuccinea columella snails transmit the trematode Fasciola hepatica, but in Cuba, six naturally occurring populations successfully resist parasite infection. Here, we present an updated distribution of P. Cuba; 68 positive sites with earliest records more abundant west-central Cuba and east-central generally corresponding to newest samples. No were found farther east. The IPA site reported 10.5% prevalence F. hepatica-infected snails. Population genetics, studied through...
Abstract In this study we present the first approach to exploration of genetic diversity Cuban Fasciola hepatica populations using microsatellite markers, coupled with observed prevalence in slaughterhouses. Nine flukes recovered from cows and buffalos were studied central-western region Cuba. The infection rates definitive hosts (bovines) 70–100% most cases. An important amount polymorphism was found four loci explored. However, no apparent differences between different provinces or bovine...
Pseudosuccinea columella is one of the most widespread vectors Fasciola hepatica, a globally distributed trematode that affects humans, livestock and wildlife. The exclusive occurrence in Cuba susceptible naturally-resistant populations to F. hepatica within this snail species, offers fascinating model for evolutionary biology, health sciences vector control strategies. In particular, resistance P. characterized by encapsulation parasite host's immune cells has been experimentally tested...
Fasciolosis is one of the food-borne neglected trematodioses that has reemerged as a human disease while its effects on domestic animal health remains significant economic consideration. Being snail-borne disease, accurate and time-saving epidemiological surveillance transmission foci where infected lymnaeid snails occur could be essential to effectively focus or redirect control strategies. For this purpose, first monoclonal antibody-based immunoenzymatic assay detect Fasciola...
Fasciolosis is a worldwide spread parasitosis mainly caused by the trematode Fasciola hepatica. This disease particularly important for public health in tropical regions, but it can also affect economies of many developed countries due to large infections domestic animals. Although several studies have tried understand transmission studying prevalence different host species, only few used population genetic approaches links between and wildlife infections. Here, we present results such...