A5022786507- Sepsis Diagnosis and Treatment
- Hernia repair and management
- Thyroid and Parathyroid Surgery
- Nosocomial Infections in ICU
- Thyroid Cancer Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Gastrointestinal disorders and treatments
- Bacterial Identification and Susceptibility Testing
- Pneumonia and Respiratory Infections
- Sarcoma Diagnosis and Treatment
- Inflammation biomarkers and pathways
- Intraperitoneal and Appendiceal Malignancies
- Abdominal Surgery and Complications
- Pelvic and Acetabular Injuries
- Head and Neck Anomalies
- Gallbladder and Bile Duct Disorders
- Neonatal and Maternal Infections
- Diverticular Disease and Complications
- Biliary and Gastrointestinal Fistulas
- Immune Response and Inflammation
- Genetic Syndromes and Imprinting
- Cardiac, Anesthesia and Surgical Outcomes
- Streptococcal Infections and Treatments
- Cancer Diagnosis and Treatment
- Intestinal and Peritoneal Adhesions
Aristotle University of Thessaloniki
2015-2024
Weatherford College
2021
Telio (Norway)
2015-2020
General Hospital of Athens G. Genimatas
2014
NIMTS Hospital
2013
Interbalkan Medical Center
2010
Although major changes of the immune system have been described in sepsis, it has never studied whether these may differ relation to type underlying infection or not. This was for first time.The statuses innate and adaptive systems were prospectively compared 505 patients. Whole blood sampled within less than 24 hours advent sepsis; white cells stained with monoclonal antibodies analyzed though a flow cytometer.Expression HLA-DR significantly decreased among patients severe sepsis/shock due...
Abstract Introduction Early risk assessment is the mainstay of management patients with sepsis. APACHE II gold standard prognostic stratification system. A prediction rule that aimed to improve prognostication by application serum suPAR (soluble urokinase plasminogen activator receptor) developed. Methods prospective study cohort enrolled 1914 sepsis including 62.2% and 37.8% severe sepsis/septic shock. Serum was measured in samples drawn after diagnosis an enzyme-immunoabsorbent assay; 367...
Development of sepsis is a process with significant variation among individuals. The precise elements this need to be defined. This study was designed define the way in which comorbidities contribute development.Three thousand five hundred nine patients acute pyelonephritis (AP), community-acquired pneumonia (CAP), intraabdominal infections (IAI) or primary bacteremia (BSI) and at least two signs systemic inflammatory response syndrome were analyzed. endpoint how as expressed Charlson's...
ABSTRACT Background: The validation of new biomarkers for the diagnosis and risk stratification patients with sepsis at an early point is essential successful treatment. Recent publications prompted us to investigate heparin binding protein (HBP) emergency department (ED) admissions. Materials Methods: In this multicenter, cross-sectional study, HBP procalcitonin (PCT) were measured within first hour upon admission ED in plasma samples 371 signs infection. Patients classified into non-sepsis...
BackgroundA previous randomized study showed that clarithromycin decreases the risk of death due to ventilator-associated pneumonia and shortens time until infection resolution. The efficacy was tested in a larger population with sepsis.
Whether or not to administer antibiotics is a common and challenging clinical decision in patients with suspected infections presenting the emergency department (ED). We prospectively validate InSep, 29-mRNA blood-based host response test for prediction of bacterial viral infections.
The aim of this study was to quantify the role time between symptom onset and surgery on changing risk perforation, evaluate possible factors leading delay operation.The files 169 patients who underwent appendectomy in our clinic over a two-year period (May 2004-June 2006) were reviewed. relative perforation calculated according "time-table" method. Time divided into intervals, initially 12 hours and, later on, 24 hours.18 found have perforated appendicitis. from symptom-onset first...
High mobility group box 1 (HMGB1) is released from macrophages as a late biomarker of sepsis. Conditions associated with pre-existing macrophage activation may modify HMGB1 expression. This study aimed to assess the impact kinetics on 28-day mortality. In sub-study previous randomized clinical trial among patients systemic inflammatory response syndrome and gram-negative infections, were classified in early peak groups. Serial measurements HMGB1, ferritin interferon-gamma (IFNγ) performed...
The development of pancreatic tissue outside the confines main gland, without anatomic or vascular connections between them, is a congenital abnormality referred to as heterotopic pancreas. A pancreas in gastrointestinal tract usually discovered incidentally and risk its malignant transformation extremely low. In this study, we describe first case endoepithelial carcinoma arising gastric 56-year old woman Greece. She presented with epigastric pain, periodic nausea vomiting....
We have previously described increased fasting plasma glucose levels in patients with normocalcemic primary hyperparathyroidism (NPHPT) and co-existing prediabetes, compared to prediabetes per se. This study evaluated the effect of parathyroidectomy (PTx) (Group A), versus conservative follow-up B), a small cohort NPHPT prediabetes. Sixteen were categorized each group. Glycemic parameters (levels (fGlu), glycosylated hemoglobin (HbA1c), insulin (fIns)), homeostasis model assessment for...