A5038290834- Memory and Neural Mechanisms
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Dementia and Cognitive Impairment Research
- Health, Medicine and Society
- Alzheimer's disease research and treatments
- Psychoanalysis and Psychopathology Research
- Neural dynamics and brain function
- Aging and Gerontology Research
- Anesthesia and Neurotoxicity Research
- Functional Brain Connectivity Studies
- Neurogenesis and neuroplasticity mechanisms
- Health and Well-being Studies
- Stroke Rehabilitation and Recovery
- Nicotinic Acetylcholine Receptors Study
- Education, sociology, and vocational training
- Memory Processes and Influences
- Cognitive Functions and Memory
- Neuroinflammation and Neurodegeneration Mechanisms
- Nerve injury and regeneration
- Aging, Elder Care, and Social Issues
- Motor Control and Adaptation
- Creativity in Education and Neuroscience
- Balance, Gait, and Falls Prevention
Laboratoire de Neurosciences Cognitives
2018-2024
Aix-Marseille Université
2007-2023
Centre National de la Recherche Scientifique
2009-2021
Laboratoire de Neurosciences Intégratives et Adaptatives
2003-2019
Centre de Recherche en Neurobiologie - Neurophysiologie de Marseille
1985
Perinatal brain injury including white matter damage (WMD) is highly related to sensory, motor or cognitive impairments in humans born prematurely. Our aim was examine the neuroanatomical, functional and behavioral changes adult rats that experienced prenatal ischemia (PI), thereby inducing WMD. PI induced by unilateral uterine artery ligation at E17 pregnant rats. We assessed performances gait, abilities topographical organization of maps, neuronal glial density primary somatosensory...
Abstract The time course of metabolic changes was investigated in the hippocampus and parietal, rhinal frontal cortices rats from 4 to 30 months old. Samples were analysed by solid‐state high‐resolution magic angle spinning nuclear magnetic resonance method. Quantification performed with quest procedure j mrui software. Eighteen metabolites identified separated spectrum. Six them not age sensitive, particular alanine, glutamine lactate. In contrast, choline, glycerophosphocholine, myo...
Multifactorial cognitive training programs have a positive effect on cognition in healthy older adults. Among the age-sensitive domains, episodic memory is most affected. In present study, we evaluated benefits of computer-based and attention training. We targeted consciously controlled processes at encoding minimizing processing retrieval, by using more familiarity than recollection during recognition. Such an approach emphasizes prevents subjects from reinforcing their own errors. Results...
The interactive effects of age and cholinergic damage were assessed behaviorally in young middle-aged rats. Rats lesioned at either 3 or 17 months by injection 192 IgG-saporin immunotoxin into the medial septum nucleus basalis magnocellularis, they then tested on a range behavioral tasks: nonmatching-to-position task T-maze, an object-recognition task, object-location open-field activity test. Depending used, only lesion effect was observed, but there no Age X Lesion interaction. Middle-aged...
This study aims to investigate the effects of individual differences in trait coping on brain networks at rest using electroencephalography (EEG) data. EEG recordings were processed graph theory analysis. Active and passive styles determined according factor structure Brief Coping Orientation Problems Experienced questionnaire. A structural equation modeling analysis indicated that influence strategies quality life varies strength direction. In particular, active positively correlated with...
Because of a dramatic increase older people worldwide, screening for prodromal state Alzheimer disease (AD) is major societal challenge. Many individuals diagnosed with AD, do not convert to some remaining stable and others reversing back normal. We argue that an important source this overdiagnosis comes from negative aging stereotypes (eg, the culturally shared beliefs inescapably causes severe cognitive decline diseases). laboratory studies show such impair memory performance in healthy...
Stereotype threat can lead older adults to perceive their experiences in a biased manner, giving rise interfering thoughts and negative emotions that generate stress anxiety. Negative beliefs about aging may serve as an additional factor increases the need for attentional demand, potentially resulting performance level below actual capabilities. In present study, we asked whether stereotypes influence dynamic balance task explored means counteract them healthy elderly participants.