A5023307847- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Lung Cancer Research Studies
- Economic and Financial Impacts of Cancer
- Multiple and Secondary Primary Cancers
- Advanced MRI Techniques and Applications
- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Cancer Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Palliative Care and End-of-Life Issues
- Cancer Treatment and Pharmacology
- Breast Cancer Treatment Studies
- Head and Neck Cancer Studies
- Medical Imaging and Pathology Studies
- Ethics in medical practice
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Treatments and Studies
- Cancer Genomics and Diagnostics
- MicroRNA in disease regulation
- Cancer Risks and Factors
- Health Systems, Economic Evaluations, Quality of Life
The University of Texas at Austin
2017-2025
Seton Medical Center Austin
2019-2022
Seton Medical Center
2018-2021
Texas Oncology
2018-2021
Ascension
2019
Texas Medical Association
2018-2019
Livestrong Foundation
2017-2019
Seton Healthcare Family
2018-2019
The University of Texas System
2018
The University of Texas Southwestern Medical Center
2013
About 30% stage I non-small cell lung cancer (NSCLC) patients undergoing resection will recur. Robust prognostic markers are required to better manage therapy options. MicroRNAs (miRNAs) a class of small non-coding RNAs 19–25 nt and play important roles in gene regulation human cancers. The purpose this study is identify miRNA expression profiles that would predict prognosis NSCLC. MiRNAs extracted from 527 NSCLC were profiled on the profiling v2 panel (Illumina). analyzed for their...
Background The incidence of colorectal cancer (CRC) in adults younger than 50 years has increased the United States over past decades according to Surveillance, Epidemiology, and End Results data. National guidelines conflict beginning screening at age 45 or years. Methods This was a retrospective study Cancer Data Base data from 2004 2015. Cochran‐Armitage test for trend used assess changes proportion cases diagnosed an identified 130,165 patients 1,055,598 older. total number with CRC rose...
The ability to accurately predict response and then rigorously optimize a therapeutic regimen on patient-specific basis, would transform oncology. Toward this end, we have developed an experimental-mathematical framework that integrates quantitative magnetic resonance imaging (MRI) data into biophysical model treatment of locally advanced breast cancer neoadjuvant therapy. Diffusion-weighted dynamic contrast-enhanced MRI is collected prior therapy, after 1 cycle at the completion first...
Background Quantitative diffusion-weighted MRI (DW-MRI) and dynamic contrast-enhanced (DCE-MRI) have the potential to impact patient care by providing noninvasive biological information in breast cancer. Purpose/Hypothesis To quantify repeatability, reproducibility, accuracy of apparent diffusion coefficient (ADC) T1-mapping community radiology practices. Study Type Prospective. Subjects/Phantom Ice-water DW-MRI T1 gel phantoms were used assess accuracy. Normal subjects (n = 3) across three...
299 Background: AI Chatbots, such as ChatGPT, are increasingly being utilized across various aspects of society, including healthcare. Despite this growing usage, their role within the field oncology remains underdeveloped. The objective study is to evaluate ChatGPT’s ability accurately respond patient inquiries regarding colon cancer by comparing its responses assessments from expert clinical oncologists. Methods: Ten comprehensive questions were compiled reviewing commonly asked reputable...
Introduction: Cutaneous squamous cell carcinoma (cSCC) is a non-melanomatous neoplasm of the skin that more likely to develop in immunosuppressed patients or those with autoimmune diseases. Individuals connective tissue disorders particular, such as scleroderma, are particularly at an increased risk developing cancer due chronic inflammation, damage, genetic susceptibility, and immunosuppressive therapy. Additionally, treatment cSCC surgery radiation therapy, especially disorders, presents...
This meta-analysis assesses the prognostic value of quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted MRI (DW-MRI) performed during neoadjuvant therapy (NAT) locally advanced breast cancer. A systematic literature search was conducted to identify studies DCE-MRI DW-MRI cancer NAT that report sensitivity specificity for predicting pathological complete response (pCR). Details study population parameters were extracted from each subsequent...
There are no reliable markers to predict recurrence in resected Stage I non-small cell lung cancer (NSCLC). A validated clinical model estimate the risk of would help select patients for adjuvant therapy.We reviewed medical records 715 who had a potentially curative resection NSCLC at our institution from 1990 2000. Recurrence rates were estimated by Kaplan-Meier method. was developed combining independent factors.With median follow-up 4.7 years, 5-year survival Stages IA and IB 66% 55%...
Introduction: The demand for comprehensive data resources has surged due to advancements in research aimed at tackling complex questions. Data integration techniques have evolved significantly, moving from the of various omics types a single patient multimodal leveraging machine and transfer learning. This evolution given rise concept digital twins facilitate silico prediction treatment response. Furthermore, emergence fusion fabric concepts highlights growing need broader connectivity,...
Abstract Background The purpose of this study was to determine whether advanced quantitative magnetic resonance imaging (MRI) can be deployed outside large, research-oriented academic hospitals and into community care settings predict eventual pathological complete response (pCR) neoadjuvant therapy (NAT) in patients with locally breast cancer. Methods Patients stage II/III cancer ( N = 28) were enrolled a multicenter performed radiology settings. Dynamic contrast-enhanced (DCE)...
7078 Background: Adjuvant chemotherapy for patients (pts) with resected NSCLC provides a modest survival benefit, but large proportion of pts still relapse, presumably due to inherent chemoresistance. Tumors activating EGFR mutations are exquisitely sensitive the tyrosine kinase inhibitors (TKIs) gefitinib and erlotinib; hence use adjuvant TKIs may more effectively prevent recurrences. This trial investigates safety efficacy erlotinib in stage I-IIIA somatic mutations. Methods: Eligible have...
Repeatability and reproducibility of magnetization transfer magnetic resonance imaging the breast, ability this technique to assess response locally advanced breast cancer neoadjuvant therapy (NAT), are determined. Reproducibility scans at 3 different T scanners, including 2 scanners in community centers, found a 16.3% difference (n = 3) ratio (MTR) healthy fibroglandular tissue. 10) ∼8.1% MTR measurement tissue between measurements. Thus, is repeatable reproducible can be integrated into...
20626 Background: Delayed nausea and vomiting following administration of carboplatin containing chemotherapy regimen remains a clinically significant problem for patients with cancer despite standard antiemetic prophylaxis (a 5-HT3 antagonist & dexamethasone). Methods: We report here preliminary results an ongoing prospective study to evaluate the incidence delayed chemotherapy-induced (CINV) after first cycle treatment. Previously untreated newly diagnosed scheduled receive (AUC 5 or...