A5102987726- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Cancer-related Molecular Pathways
- Abdominal vascular conditions and treatments
- Glioma Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Meningioma and schwannoma management
- Pancreatic and Hepatic Oncology Research
- Liver physiology and pathology
- Mast cells and histamine
- Immunotherapy and Immune Responses
- Coronary Interventions and Diagnostics
- Animal Virus Infections Studies
- Urinary Bladder and Prostate Research
- Viral-associated cancers and disorders
- Prostate Cancer Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Cancer Genomics and Diagnostics
- Hepatitis Viruses Studies and Epidemiology
- Dental Implant Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Systemic Lupus Erythematosus Research
- Myasthenia Gravis and Thymoma
Athens Medical Center
2022
Jena University Hospital
2016-2021
Sismanoglio General Hospital
2020-2021
Diamant (Germany)
2019
Friedrich Schiller University Jena
2019
Hirslanden Klinik Linde
2016
University General Hospital Attikon
2006-2010
National and Kapodistrian University of Athens
2010
University Hospital of Heraklion
2003-2006
University of Crete
2003-2004
Background: Fractional flow reserve (FFR) is a reliable tool for the functional assessment of coronary stenoses. FFR computed tomography (CT) derived (FFR CT ) has shown to be accurate, but its clinical usefulness in patients with complex artery disease remains investigated. The present study sought determine impact on heart team’s treatment decision-making and selection vessels revascularization 3-vessel disease. Methods: trial was an international, multicenter randomizing 2 teams make...
Piscuoglio S, Zlobec I, Pallante P, Sepe R, Esposito F, Zimmermann A, Diamantis Terracciano L, Fusco A & Karamitopoulou E (2012) Histopathology 60, 397–404 HMGA1 and HMGA2 protein expression correlates with advanced tumour grade lymph node metastasis in pancreatic adenocarcinoma Aims: Pancreatic ductal follows a multistep model of progression through precursor lesions called intraepithelial neoplasia (PanIN). The high mobility group A1 (HMGA1) A2 (HMGA2) proteins are architectural...
Abstract: Background/Aim: The aim of this study was to find a non‐invasive marker, which could predict liver fibrosis without the need biopsy in non‐alcoholic steatohepatitis (NASH). Patients/Methods: Fifty patients were included. All had one or more conditions that characterize metabolic syndrome and histological proven NASH. Hyaluronic acid (HA), leptin (LT) laminin (LN) determined from serum withdrawn at day biopsy. Results: Patients divided into two groups according findings. first group...
Forty-five extrahepatic bile duct carcinomas (i.e., tumors of the region proximal to junction, including Klatskin tumors, lower mid-region, and ampulla Vater) 11 gallbladder were immunohistochemically examined for p53 protein expression, using DO-7 monoclonal (mAb) CM-1 polyvalent (pAb) antibodies an antigen retrieval method. Because mAb was found be significantly more reliable than pAb in detecting immunoreactivity, immunohistochemical results obtained with former antibody used comparing...
Cholangiocarcinoma is the second most common malignant tumor of liver. We analyzed, immunohistochemically, significance cell cycle- and apoptosis-related markers in 128 cholangiocarcinomas (42 intrahepatic, 70 extrahepatic, 16 gallbladder carcinomas) combined a tissue microarray. Follow-up was available for 57 patients (44.5%). In comparison with normal (29 specimens), expressed significantly more frequently p53, bcl-2, bax, COX-2 (P.05 <). Intrahepatic tumors were bcl-2+ p16+, whereas...
Kupffer cells (KC) and lipopolysaccharide (LPS) interaction is the initial event leading to hepatic inflammation fibrosis in many types of liver injury. We studied chemokine secretion by KC activated with LPS possible effect somatostatin analogue octreotide, regulation this process. isolated from Sprague-Dawley rats were cultured presence added alone or different concentrations octreotide for 24 48 h, production was assessed culture supernatants ELISA. CC mRNA expression semiquantitative...
Autocrine interleukin 3 (IL-3)-secreting tumors were generated from an IL-3-dependent mouse mast cell line (PB-3c) after introduction of the v-H-ras oncogene. Tumor progression was characterized by four distinct phenotypes. The first corresponded to immortalized cells unresponsive oncogenic effect v-H-ras. second expressed in a clonable subpopulation PB-3c and marked competence form v-H-ras-dependent (immortalized transformation competence). third direct expression on all vitro reduced IL-3...
Abstract Purpose To evaluate the effect of cone-beam computed tomography (CBCT) on radiation exposure, procedure time, and contrast media (CM) use in prostatic artery embolization (PAE). Materials Methods Seventy-eight patients were enrolled this retrospective, single-center study. All received PAE without (group A; n = 39) or with B; CBCT. Total dose-area product (DAP total ; Gycm 2 ), entrance skin dose (ESD mGy), effective (ED mSv) primary outcomes. Number digital subtraction angiography...
Abstract Purpose To evaluate the response rate and safety of superselective drug-eluting beats transarterial chemoembolization (DEB-TACE) with doxorubicin-loaded 40-µm microspheres in patients hepatocellular carcinoma (HCC). Methods One hundred forty-one treatments 83 between 2012 2017 were retrospectively evaluated. Images treated lesions analyzed before after each treatment according to mRECIST (modified Response Evaluation Criteria Solid Tumors). Therapy (complete [CR] + partial [PR])...
To assess the presence of anticardiolipin antibodies (ACAs) in patients with chronic hepatitis B virus (HBV) infection, D (HDV) infection and HBV-related hepatocellular carcinoma (HCC) to associate this incidence portal vein thrombosis (PVT) HCC patients.Sixty-five cirrhotic HCC, 28 naive HBV 14 HDV were enrolled prospectively study. Thirty-two healthy blood donors used as controls. The ACAs (immunoglobulin G immunoglobulin M) measured using an enzyme-linked immunosorbent assay system....
The demonstration of a physiological benefit has recently become an indispensible element the definition dietary fibers. In here-reported pilot study, effect alpha-cyclodextrin (alpha-CD) on postprandial glycemic and insulinemic starch was examined. Twelve fasted, healthy male volunteers received, three subsequent days, test breakfast consisting (A) 100 g fresh white bread (providing 50 starch) 250 mL drinking water, (B) same with supplement 10 alpha-CD dissolved in (C) 25 water. Capillary...
Abstract Purpose To assess radiation exposure in men undergoing prostate artery embolization (PAE) for the treatment symptomatic, benign prostatic hyperplasia depending on growing experience of interventional radiologists over a 4-year period. Methods A total 250 consecutive patients underwent PAE at single center. Data [dose area product (DAP), effective dose (ED), entrance skin (ESD), and fluoroscopy time (FT)] were retrospectively evaluated. Primary outcomes interest patient five groups...
Autocrine interleukin 3 (IL-3)-secreting tumors were generated from an IL-3-dependent mouse mast cell line (PB-3c) after introduction of the v-H-ras oncogene. Tumor progression was characterized by four distinct phenotypes. The first corresponded to immortalized cells unresponsive oncogenic effect v-H-ras. second expressed in a clonable subpopulation PB-3c and marked competence form v-H-ras-dependent (immortalized transformation competence). third direct expression on all vitro reduced IL-3...