A5102749036- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- Dementia and Cognitive Impairment Research
- Neurobiology of Language and Bilingualism
- EEG and Brain-Computer Interfaces
- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Alzheimer's disease research and treatments
- Spatial Neglect and Hemispheric Dysfunction
- Neurological disorders and treatments
- Action Observation and Synchronization
- Advanced MRI Techniques and Applications
- Stroke Rehabilitation and Recovery
- Genetic Neurodegenerative Diseases
- Memory and Neural Mechanisms
- Advanced Neuroimaging Techniques and Applications
- Parkinson's Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Mitochondrial Function and Pathology
- Cholinesterase and Neurodegenerative Diseases
- Cognitive Functions and Memory
- Mental Health and Psychiatry
- Neuroscience and Neuropharmacology Research
- Psychosomatic Disorders and Their Treatments
- Hemispheric Asymmetry in Neuroscience
Centro San Giovanni di Dio Fatebenefratelli
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
University of Brescia
1999-2019
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2001-2009
University of Turin
2007
University of Milan
1999
University of Rochester
1999
National Research Council
1999
<h3>Objectives</h3> Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a possible treatment for the cognitive deficits associated with Alzheimer disease (AD). The aim of this study was to assess long-term effects, on performance, rTMS applied left dorsolateral prefrontal cortex (DLPFC) in AD patients. <h3>Methods</h3> Ten patients were randomly assigned one two groups. Multiple-baseline design used.The first group underwent 4-week real protocol, while second 2-week...
To assess whether exposure to non-invasive brain stimulation with transcranial alternating current at γ frequency (γ-tACS) applied over Pz (an area overlying the medial parietal cortex and precuneus) can improve memory modulate cholinergic transmission in mild cognitive impairment due Alzheimer's disease (MCI-AD).In this randomized, double-blind, sham controlled, crossover pilot study, participants were assigned a single 60 min treatment γ-tACS or tACS. Each subject underwent clinical...
This study aimed to assess whether non-invasive brain stimulation with transcranial alternating current at gamma-frequency (γ-tACS) applied over the precuneus can improve episodic memory and modulate cholinergic transmission by modulating cerebral rhythms in early Alzheimer's disease (AD).In this randomized, double-blind, sham controlled, crossover study, 60 AD patients underwent a clinical neurophysiological evaluation including assessment of pre post minutes treatment γ-tACS targeting or...
Objective: Word‐finding difficulty (anomia) is commonly observed in Alzheimer’s dementia (AD). The aim of this study was to assess the effect repetitive transcranial magnetic stimulation (rTMS) applied dorso‐lateral prefrontal cortex (dlPFC) on picture naming 24 probable AD patients with different degrees cognitive decline. Methods: High‐frequency rTMS left and right dlPFC during object action patients. A sham used as a control condition. Results: Whilst, previously reported, both improved...
Action naming has been reported to be disproportionately impaired in comparison object patients with frontotemporal dementia (FTD). This finding attributed the crucial role of frontal cortex action naming. The investigation and different subtypes FTD, as well related conditions progressive supranuclear palsy (PSP) corticobasal degeneration (CBD), may thus contribute elucidation cerebral correlates action-object discrepancy provide clues underlying cognitive mechanisms. results indicated...
Objective: To assess the effect of repetitive transcranial magnetic stimulation (rTMS) to dorsolateral prefrontal cortex (DLPFC) on picture naming in patients with Alzheimer disease (AD).Design: Experimental study.Patients AD underwent rTMS real and control conditions during picturenaming tasks.
Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim present study is investigate effects anodal tDCS (AtDCS) combined with memory training on face-name associations an AD patient sample.Thirty six patients were randomly assigned one three groups: Group 1, AtDCS plus individualized computerized training; 2, placebo 3, motor training.A general improvement performance...
Primary progressive aphasia (PPA) is an untreatable neurodegenerative disorder that disrupts language functions. Previous studies have demonstrated transcranial direct current stimulation (tDCS) may improve symptoms in patients with post stroke or diseases.The present study investigated whether the application of anodal tDCS (AtDCS) to scalp overlying left dorsolateral prefrontal cortex (DLPFC), which increase cortical excitability, combination individualized speech therapy would naming...
Parkinson's disease (PD) is characterized by both motor and cognitive deficits. In PD, physical exercise has been found to improve functioning. Recent studies demonstrated that repeated sessions of transcranial direct current stimulation led an increased performance in tasks patients with PD.The present study investigated the effects anodal applied over dorsolateral prefrontal cortex combined therapy PD patients.A total 20 were assigned 1 2 groups: group 1, plus (n = 10) or 2, placebo 10)....
Memory is the capacity to store, maintain, and retrieve events or information from mind. Difficulties in verbal episodic memory commonly occur healthy aging. In this paper, we assess hypothesis that anodal transcranial direct current stimulation (tDCS) applied over dorsolateral prefrontal cortex (DLPFC) parietal (PARC) could facilitate a group of 32 older adults young subjects relative sham using single-blind randomized controlled design. Each participant underwent two sessions tDCS (left...
Background and Objective Numerous studies have highlighted the possibility of modulating excitability cerebellar circuits using transcranial direct current stimulation. The present study investigated whether a single session anodal stimulation could improve symptoms in patients with ataxia. Methods Nineteen ataxia underwent clinical functional evaluation pre- post-double-blind, randomized, sham, or Results There was significant interaction between treatment time on Scale for Assessment...
Memory consolidation is a dynamic process. Reactivation of consolidated memories by reminder triggers reconsolidation, time-limited period during which existing can be modified (i.e., weakened or strengthened). Episodic memory refers to our ability recall specific past events about what happened, including where and when. Difficulties in this form long-term commonly occur healthy aging. Because episodic critical for daily life functioning, the development effective interventions reduce loss...
Abstract Gender differences in social cognition are a long discussed issue, particular those concerning Theory of Mind (ToM), i.e., the ability to explain and predict other people’s mental states. The aim this randomized, double-blind, placebo-controlled study was test hypothesis that anodal tDCS over medial prefrontal cortex (mPFC) selectively enhances cognitive ToM performance females. In first experiment we administered sixteen females males task during or placebo mPFC. second further...
The present study aimed to assess the ability in objects and actions naming Parkinson's disease (PD) patients. Further, we wished effect of a particular conceptual dimension, i.e. manipulability, on object actions. Patients were recruited from Department Neurology, University Brescia. Thirty-two diagnosed as PD, according published criteria, 15 healthy volunteers matched age education patients' sample. All patients underwent detailed clinical neurological evaluation. stimuli used...
This study aimed to explore the effects of transcranial direct current stimulation (tDCS) on physiologically aging adults performing a naming task. tDCS is method that modulates human cortical excitability. Neuroplasticity considered have its foundation in excitability as property adjusts connection strength between neurons brain. Language efficiency, all functions, relies integration information (i.e., effectiveness connectivity) through So use tDCS, modulate excitability, can help define...