Lívia Spíndola

ORCID: 0000-0003-3215-308X
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About
Contact & Profiles
Research Areas
  • Dementia and Cognitive Impairment Research
  • Cognitive Functions and Memory
  • Aging, Elder Care, and Social Issues
  • Health disparities and outcomes
  • EEG and Brain-Computer Interfaces
  • Heart Rate Variability and Autonomic Control
  • Clinical Reasoning and Diagnostic Skills
  • Autoimmune Neurological Disorders and Treatments
  • Elder Abuse and Neglect
  • Psychological Well-being and Life Satisfaction
  • Intracranial Aneurysms: Treatment and Complications
  • Mental Health Treatment and Access
  • Functional Brain Connectivity Studies
  • Ophthalmology and Visual Health Research
  • Decision-Making and Behavioral Economics
  • Health, Environment, Cognitive Aging
  • Health Systems, Economic Evaluations, Quality of Life
  • Diet and metabolism studies
  • Public Health in Brazil
  • Stroke Rehabilitation and Recovery
  • Epilepsy research and treatment
  • Cognitive Abilities and Testing
  • Neurobiology of Language and Bilingualism
  • Neurological Disorders and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2021

Universidade de São Paulo
2009-2017

Hospital de Clínicas de Porto Alegre
2013

Brazilian Institute of Neuropsychology and Behaviour
2011

The prevalence of cognitive impairment is insufficiently determined in developing countries. aim this study was to ascertain the without dementia and community-dwelling elderly Brazil.This a single-phase cross-sectional survey (aged 60 years above) living municipality Tremembé, Brazil. Twenty percent households with persons were randomly selected from urban rural areas, obtain homogenous representation all socioeconomic cultural levels.We assessed 630 individuals [mean age, 71.3 y (±7.99);...

10.1097/wad.0000000000000122 article EN Alzheimer Disease & Associated Disorders 2015-12-02

Abstract Introduction Mild cognitive impairment (MCI) is classically considered a transitional stage between normal aging and dementia. Non-amnestic MCI (naMCI) patients, however, typically demonstrate deficits other than memory decline. Furthermore, as group, naMCI have lower rate of an eventual dementia diagnosis compared to amnestic subtypes (aMCI). Unfortunately, studies investigating biomarker profiles are scarce. The study objective was investigate the regional brain glucose metabolism...

10.1186/s13195-015-0143-0 article EN cc-by Alzheimer s Research & Therapy 2015-09-15

Background: Aerobic training (AT) is a promising intervention for mild cognitive impairment (MCI). Objective: To evaluate the effects of AT on cognition and regional brain glucose metabolism (rBGM) in MCI patients. Methods: Subjects performed twice-a-week, moderate intensity, program 24 weeks. Assessment with ADAS-cog, comprehensive neuropsychological battery, evaluation rBGM positron emission tomography 18F-fluorodeoxyglucose ([18F]FDG-PET) were before after intervention. capacity was...

10.3233/jad-150033 article EN Journal of Alzheimer s Disease 2015-06-25

It is not easy to differentiate patients with mild cognitive impairment (MCI) from subjective memory complainers (SMC). Assessments screening tools are essential, particularly in primary care where most seen. The objective of this study was evaluate the diagnostic accuracy tests and propose a score derived tests. Elderly subjects complaints were evaluated using Mini Mental State Examination (MMSE) Brief Cognitive Battery (BCB). We added two delayed recalls MMSE (a recall late-delayed recall,...

10.4081/ni.2013.e16 article EN cc-by Neurology International 2013-09-05

Abstract Mild Cognitive Impairment (MCI) can be an intermediate state between normality and dementia in some patients. An early diagnosis, through neuropsychological assessment, could identify individuals at risk of developing dementia. Objective: To verify differences performance on tests among controls, amnestic MCI (aMCI) Alzheimer’s disease (AD) Methods: Sixty-eight AD patients (mean age 73.77±7.24; mean schooling 9.04±4.83; 40 women 28 men), 34 aMCI 74.44±7.05; 12.35±4.01; 20 women) 60...

10.1590/s1980-57642009dn30100009 article EN cc-by Dementia & Neuropsychologia 2009-03-01

Depression is a major growing public health problem. Many population studies have found significant relationship between depression and the presence of cognitive disorders. OBJECTIVE: To establish correlation Visual Analogue Scale Happiness Cornell for in Dementia aged 60 years or over city Tremembé, state São Paulo, Brazil. METHODS: An epidemiological survey involving home visits was carried out Tremembé. The sample randomly selected by drawing 20% older from each city's census sectors. In...

10.1590/s1980-57642014dn84000014 article EN cc-by Dementia & Neuropsychologia 2014-12-01

Depression is a heterogeneous mental disease classified as set of disorders, which manifest with certain duration, frequency and intensity. The prevalence depression in the elderly ranges from 0.5 to 16%.To establish, an epidemiological study, significant depressive symptoms population aged 60 years or older.Results cross-sectional involving home visits, being carried out city Tremembé, Brazil, were reported. sample was randomly selected by drawing 20% over each city's census sectors. In...

10.1590/s1980-57642013dn70300004 article PT cc-by Dementia & Neuropsychologia 2013-09-01

Electroencephalographic (EEG) coherence is a parameter that enables evaluation of cerebral connectivity. It may be related to the functional state brain. In elderly, it reflect neuronal loss caused by aging. To describe characteristics in nonagenarians.We evaluated interhemispheric for alpha band 42 cognitively normal individuals aged 90 101 years. Coherence values occipital electrode (O1O2), resting with closed eyes, were calculated means spectral analysis using digital EEG EMSA 32...

10.1590/0004-282x20170102 article EN cc-by-nc Arquivos de Neuro-Psiquiatria 2017-09-01

Working memory (WM) is vital for other cognitive functions and the maintenance of activities daily life. It known to follow a trajectory marked decline in aging. WM training may enhance performance facilitate autonomy older people. This study aimed investigate impact an-eight-session on psychological well-being (PWB) adults without dementia depression. The PWB has rarely been investigated. In all, 31 individuals received (EG) 29 took part wait list control group (CG). Pre post-test protocols...

10.1016/j.jalz.2015.06.481 article EN Alzheimer s & Dementia 2015-07-01

ABSTRACT. Judgment is the ability to make sound decisions after consideration of relevant information, possible solutions, likely outcomes, and contextual factors. Loss judgment common in patients with mild cognitive impairment (MCI) dementia. The Test Practical (TOP-J) evaluates practical adults elderly, 15- 9-item versions that require individuals listen scenarios about everyday problems report their solutions. Objective: Adaptation TOP-J for a Brazilian sample, preparation reduced version...

10.1590/1980-57642021dn15-020007 article EN cc-by Dementia & Neuropsychologia 2021-04-01

Judgment is the ability to make sound decisions after careful consideration of available information, possible solutions, likely outcomes and contextual factors. From a neuropsychological perspective, concept judgment involves memory, language, sustained attention, reasoning specially executive functions. Loss has been described in Mils Cognitive Impairment (MCI). The Test Practical (TOP-J) an originally American measure, created for evaluate everyday older adults. It 15-item open-ended...

10.1016/j.jalz.2014.05.921 article EN Alzheimer s & Dementia 2014-07-01

Mild cognitive impairment (MCI) is a syndrome that may have several etiologies. It general consensus amnestic forms of MCI (aMCI) can be symptomatic pre-dementia phase Alzheimer's disease (AD), while non-amnestic (naMCI) are due to other diseases than AD. Accordingly, biomarkers AD should different in and MCI. The objective this study was compare cerebrospinal fluid (CSF) biomarkers, magnetic resonance image (MRI) positron emission tomography with 18 F-fluordeoxyglucose (FDG-PET) among...

10.1016/j.jalz.2013.05.498 article EN Alzheimer s & Dementia 2013-07-01

Memory problem is a frequent complaint faced by health care providers in primary care. In busy daily practice where time an important and limiting factor, coupled with the unavailability of formal neuropsychological testing for all patients, epidemiological data bedside cognitive evaluation could be clues to correct diagnostic. The objective this study was evaluate socio-demographic profiles that may help differentiate patients mild impairment (MCI) memory (MC) screening medical appointment....

10.1016/j.jalz.2012.05.1459 article EN Alzheimer s & Dementia 2012-07-01
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