A5101847329- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiomics and Machine Learning in Medical Imaging
- Transplantation: Methods and Outcomes
- Lung Cancer Treatments and Mutations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory viral infections research
- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- Occupational and environmental lung diseases
- Antifungal resistance and susceptibility
- Cancer Treatment and Pharmacology
- Pleural and Pulmonary Diseases
- Advanced MRI Techniques and Applications
- COVID-19 Clinical Research Studies
- Pericarditis and Cardiac Tamponade
- Infective Endocarditis Diagnosis and Management
- Organ Transplantation Techniques and Outcomes
- Infectious Diseases and Mycology
- COVID-19 diagnosis using AI
- Congenital Heart Disease Studies
- Elasticity and Material Modeling
- Image and Signal Denoising Methods
- Colorectal Cancer Treatments and Studies
Johns Hopkins Medicine
2023
Johns Hopkins University
2023
University of Dundee
2020
University of Toronto
2009-2019
University Health Network
2010-2019
London Health Sciences Centre
2018-2019
Western University
2018
St Joseph's Health Care
2018
Women's College Hospital
2010-2017
Mount Sinai Hospital
2004-2017
Abstract Background Hodgkin's lymphoma (HL) survivors who undergo radiotherapy experience increased risks of second cancers (SC) and cardiac sequelae. To reduce such risks, extended-field (RT) for HL has largely been replaced by involved field (IFRT). While it generally assumed that IFRT will SC there are few data quantify the reduction in dose to normal tissues associated with modern RT practice patients mediastinal HL, no estimates expected risk. Methods Organ-specific dose-volume...
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have proven efficacy in advanced non-small-cell lung cancer (NSCLC). Their role early-stage NSCLC has not been established. Our purpose was to explore the use of preoperative gefitinib clinical stage I assess tumor response, toxicity, and molecular predictors response.Patients received 250 mg/d for up 28 days, followed by mediastinoscopy surgical resection an open-label, single-arm study. Tumor response evaluated...
Purpose To assess the prevalence and nature of incidental findings (IF) seen in low-dose computed tomographies (LDCT) from a lung cancer screening study for at-risk individuals. Materials Methods Radiology reports LDCTs 4073 participants were retrospectively reviewed other than nodules, that is, IFs, which regarded as actionable. The frequency, nature, expected cost these their anticipated follow-up estimated. Results There 880 IFs described 782 (19%); median age was 62 years (range, 46–80...
To determine whether there are thin-section computed tomographic (CT) features that predict bronchiolitis obliterans syndrome (BOS) in lung transplant recipients before the clinical appearance and during early stages of disease.Two hundred ninety-eight CT scans obtained 26 who did (study group) not (control develop BOS were reviewed for presence mosaic perfusion, bronchiectasis, bronchial wall thickening, air trapping. was defined by using recently revised definition International Society...
The purpose of this article is to address the implications invasive diagnostic procedures recommended by a lung cancer screening protocol. In particular, we assess how many were for benign nodules.Between 2003 and 2009, 4782 high-risk current former smokers enrolled in study. A helical low-dose CT chest was performed. Morphologic features targeted parenchymal nodules. indication biopsy made according algorithm provided International Early Lung Cancer Action Program. We recorded time points...
Quantifying the mechanical behaviors of soft biological tissues is considerable research interest. However, validity and reproducibility between different researchers apparatus questionable. This study aims to quantify properties myocardium while investigating methodologies that can standardize tissue testing.Tensile testing was performed obtain Young's modulus a dynamic analysis (DMA) determined viscoelastic properties. A frequency range 0.5 Hz (30bpm) 3.5 (210bpm) analyzed. For tensile...
To review radiographic findings of patients with probable severe acute respiratory syndrome (SARS) who were seen at a University Toronto (Ontario, Canada) teaching hospital.Findings reviewed for 40 fulfilled the World Health Organization criteria SARS. A template was designed analysis each serial radiograph to observe patterns and distribution disease, interval changes, complications. The majority radiographs anteroposterior views. clinical database these also collected clinical-radiologic...
Background: Although molecular testing has become standard in managing advanced nonsquamous non-small-cell lung cancer (nsclc), most patients undergo minimally invasive procedures, and the diagnostic tumour specimens available for are usually limited. A knowledge translation initiative to educate specialists about sampling techniques laboratory processes was undertaken improve uptake application of cancer. Methods: multidisciplinary panel physician experts including pathologists,...
The purpose of this pilot study was to evaluate the safety and efficacy preoperative computed tomography (CT)-guided percutaneous microcoil lung nodule localization without pleural marking compared with established technique marking.Sixty-three consecutive patients (66.7% female, mean age 61.6±11.4 y) 64 nodules resected between October 2008 January 2014 were retrospectively evaluated. Of nodules, 29.7% (n=19) had deployment (control group) 70.3% (n=45) (pilot group). Clinical, pathologic,...
Tuberculosis is very rampant disease in LMICs, which has the potential to infect almost every organ/tissue of body. Subdural empyema (SDE) suppurative infection subdural space confined between duramater and arachnoid mater. In this study we present a case report 66 year old male presenting with pus discharge from right side temporal skin flap for 1 month post autologous cranioplasty was clinically diagnosed as SDE after radiological investigations, underwent removal infected flap. The sent...