Background —Spinal cord stimulation (SCS) has been shown to have antianginal and anti-ischemic effects in severe angina pectoris. The present study was performed investigate whether SCS can be used as an alternative coronary artery bypass grafting (CABG) selected patient groups, ie, patients with no proven prognostic benefit from CABG increased surgical risk. Methods Results —One hundred four were randomized (SCS, 53; CABG, 51). assessed respect symptoms, exercise capacity, ischemic ECG...

To investigate the effects of spinal cord stimulation on myocardial ischaemia, coronary blood flow, and oxygen consumption in angina pectoris induced by atrial pacing.The heart was paced to during a control phase treatment with stimulation. Blood samples were drawn from peripheral artery sinus.Multidisciplinary pain centre, department medicine, Ostra Hospital, Wallenberg Research Laboratory, Sahlgrenska Gothenburg, Sweden.Twenty patients intractable pectoris, all stimulator implanted before...

The short term effects of epidural spinal electrical stimulation were studied in 10 patients with angina pectoris New York Heart Association functional class III or IV. antianginal pharmacological treatment given at entry to the study was regarded as optimal and not changed during study. measured by repeated bicycle ergometer tests. Treatment increased patients' working capacity, decreased ST segment depression, time angina, reduced recovery time. observed did seem be correlated any changes...

The pain-relieving effects of transcutaneous electrical nerve stimulation (TENS) were investigated in patients with severe angina pectoris first respect to systemic and coronary hemodynamics myocardial metabolism during pacing-induced second a controlled long-term study. Two series (NYHA class III IV) studied (13 the pacing study 23 study). In there was increased tolerance (142 +/- compared 124 20 beats/min tolerated, p less than .001), improved lactate (2 36% -18 43%, .01), pronounced ST...

Abstract Background Chronic pain constitutes a substantial socio‐economic challenge but little is known about its actual cost. Aim To estimate the direct and indirect costs of patients with diagnosis related to chronic ( DRCP ), determine variation in these across different groups, identify what resources constitute most important components costs. Methods Patient level data from three administrative registries Västra Götalandsregionen Sweden including inpatient outpatient care,...

<h3>OBJECTIVE</h3> To determine morbidity and mortality characteristics in patients treated with electrical neuromodulation for refractory angina pectoris. <h3>DESIGN</h3> A retrospective multicentre study of spinal cord stimulation between 1987 1997; 21 centres were contacted 14 responded. <h3>SETTING</h3> Specialist worldwide. <h3>PATIENTS</h3> Questionnaires returned on 517 patients, whom 71% male. One was lost to follow up. Mean (SD) age 63.9 (10.1) years. Duration pectoris 8.1 (6.3)...

A double-blind, randomized, placebo-controlled cross-over multi-center study was conducted to evaluate the efficacy and safety of gabapentin in treatment neuropathic pain caused by traumatic or postsurgical peripheral nerve injury, using doses up 2400 mg/day. The comprised a run-in period two weeks, periods five weeks separated three weeks’ washout period. primary variable change mean intensity score from baseline last week treatment. Other variables included relief, health related quality...

Transcutaneous electrical nerve stimulation (TNS) was used on 20 patients with severe wrist pain due to rheumatoid arthritis. Three different frequencies were used: high frequency 70 Hz (70 TNS), low 3 (3TNS) and brief trains of stimuli an internal a repetition rate (3–70 TNS). The analgesic effect evaluated the patient's own estimate relief by means loading test in which length time patient could hold weight before after TNS used. patients' corresponded well. After TNS, 18 double their...

The pain-relieving effect of transcutaneous electrical nerve stimulation (TENS) was studied in 10 male patients with angina pectoris functional class III or IV. All had been stabilized on long-term maximal oral treatment for at least six months. effects the TENS were measured by means repeated bicycle ergometer tests. an increased working capacity (16–85%) and decreased ST depression reduced recovery time during TENS. No adverse observed.

<h3>Objective</h3> To assess the long-term effect of spinal cord stimulation (SCS) on angina symptoms and quality life in patients with refractory pectoris defined as severe due to coronary artery disease resistant conventional pharmacological therapy and/or revascularisation. <h3>Methods</h3> During 2003–2005, all referred for SCS treatment at 10 European centres were consecutively included registry (European Angina Registry Link, EARL), a prospective, 3-year follow-up study. In present...

AbstractObjective: Post-traumatic brain injury symptoms, such as mental fatigue, have considerable negative impacts on quality-of-life. In the present study effects of methylphenidate in two different dosages were assessed with regard to pain and cognitive functions persons who had suffered a traumatic injury.Methods: Fifty-one subjects included 44 completed study. The treatment continued for 12 weeks, including three periods no medication 4 administration low dose (up 5 mg × 3) weeks normal...

The neurobehavioural symptoms and pain following traumatic brain injury (TBI) can be long-lasting. condition impairs the persons' ability to function in their work, studies gatherings with family friends. aim of this study was investigate dosage, safety effects methylphenidate on mental fatigue pain.Twenty-nine physically-well rehabilitated TBI victims, 28 a mild one also neck, shoulders head were included study. Methylphenidate tested each patient using three treatment strategies: no...

Objectives Traumatic brain injury (TBI) may cause long-lasting post-concussive symptoms, such as mental fatigue and concentration difficulties, this become the main hindrance for returning to work studies. There is currently no effective treatment fatigue. In hypothesis generating study, long-term effects of methylphenidate on fatigue, cognitive function, safety were assessed. Materials & methods Thirty participants who suffered from post-concussion symptoms after a mild TBI or moderate had...

Earlier studies have shown that spinal cord stimulation (SCS) has antianginal and anti-ischemic effects in severe coronary artery disease. In the present study, 14 patients were subjected to right-sided atrial catheterization pacing. The paced angina during a control session stimulation. Myocardial extraction of β-endorphin (BE) pacing (8 ± 22%) changed release at maximum rate treatment (–21 47%, negative value representing release). Furthermore, results indicate local myocardial turnover...

Background Patients with angina pectoris normal coronary arteriograms, also known as Syndrome X (typical exercise-induced pectoris, positive exercise testing, and arteriograms), are often difficult to treat conventional forms of medical therapy. Spinal cord stimulation has been used in recent years for the treatment severe refractory surgical therapy artery disease. The aim this study was investigate effects spinal on arteriograms. Methods Twelve patients underwent five bicycle tests, three...

The present study is a 2-year follow-up of the 104 patients participating in ESBY (Electrical Stimulation versus Coronary Artery Bypass Surgery Severe Angina Pectoris), randomised prospective including with increased surgical risk and no prognostic benefit from revascularisation. Hospital care costs, morbidity causes death after spinal cord stimulation (SCS) coronary artery bypass grafting (CABG) were assessed, as well complication rate SCS treatment. proved to be less expensive symptomatic...