A5069977265- Marine Bivalve and Aquaculture Studies
- Marine Biology and Ecology Research
- Calcium Carbonate Crystallization and Inhibition
- Immune Cell Function and Interaction
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Marine Ecology and Invasive Species
- Paleontology and Stratigraphy of Fossils
- Aquaculture disease management and microbiota
- Bone Metabolism and Diseases
- Neurobiology and Insect Physiology Research
- Developmental Biology and Gene Regulation
- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- Ocean Acidification Effects and Responses
- Marine Invertebrate Physiology and Ecology
- Invertebrate Immune Response Mechanisms
- Genomics and Chromatin Dynamics
- Insect and Arachnid Ecology and Behavior
- Congenital heart defects research
- Antibiotic Resistance in Bacteria
- Geological and Geophysical Studies
- Echinoderm biology and ecology
- Aquaculture Nutrition and Growth
- Cephalopods and Marine Biology
University of Concepción
2008-2024
Icahn School of Medicine at Mount Sinai
2024
Dr. A. Ramachandran's Diabetes Hospitals
2024
The University of Queensland
2013-2021
University of Bergen
2018-2019
Google (United States)
2013
Tyrosinases, tyrosinase-related proteins, catechol oxidases and hemocyanins comprise the type-3 copper protein family are involved in a variety of biological processes, including pigment formation, innate immunity oxygen transport. Although this is present three domains life, its origin early evolution not well understood. Previous analyses proteins largely have focussed on specific animal plant phyla.Here, we combine genomic, phylogenetic structural to show that original possessed signal...
Molluscs fabricate shells of incredible diversity and complexity by localized secretions from the dorsal epithelium mantle. Although distantly related molluscs express remarkably different secreted gene products, it remains unclear if evolution shell structure pattern is underpinned differential co-option conserved genes or integration lineage-specific into mantle regulatory program. To address this, we compare transcriptomes 11 bivalves gastropods varying relatedness. We find that each...
Abstract Intensive fish culture is a practice in aquaculture systems; however, it can produce negative environmental impacts due to the accumulation of organic nitrogen from feeding procedures, but also wasting products. Recirculating systems have emerged as one strategy reduce these impacts, maintaining healthy environment for fish. These toxicity level through nitrifying biofilters, which use microbial consortium convert ammonia into nitrate. The main component bacterial comprised by...
Echinoids are key components of modern marine ecosystems. Despite a remarkable fossil record, the emergence their crown group is documented by few specimens unclear affinities, rendering early history uncertain. The origin sand dollars, one its most distinctive clades, also due to an unstable phylogenetic context. We employ 18 novel genomes and transcriptomes build phylogenomic dataset with near-complete sampling major lineages. With it, we revise phylogeny divergence times echinoids, place...
Ctenostomes are a group of gymnolaemate bryozoans with an uncalcified chitinous body wall having few external, skeletal characters. Hence, species identification is challenging and their systematics remain poorly understood, even more so when they exhibit endolithic (boring) lifestyle. Currently, there four Recent families that live inside mineralized substrates like mollusk shells. In particular, Penetrantiidae Silén, 1946 has received considerable attention its systematic affinity to...
The lysine (K)-rich mantle protein (KRMP) and shematrin families are unique to the organic matrices of pearl oyster shells. Similar other proteins that constituents tough, extracellular structures, such as spider silk, shematrins KRMPs, contain repetitive, low-complexity domains (RLCDs). Comprehensive analysis available gene sequences in three species using BLAST hidden Markov models reveal both have large memberships these species. family expanded before speciation oysters, leading a...
Neuropeptides are neurosecretory signaling molecules in protostomes and deuterostomes (together Nephrozoa). Little, however, is known about the neuropeptide complement of sister group Nephrozoa, Xenacoelomorpha, which together form Bilateria. Because members xenacoelomorph clades Xenoturbella, Nemertodermatida, Acoela differ extensively their central nervous system anatomy, reconstruction bilaterian complements may provide insights into relationship between evolution peptidergic signaling....
Klebsiella pneumoniae is a resistant pathogen involved primarily in hospital-acquired infections. This characterized by its notorious resistance to last-line antibiotics, such as carbapenems.
The vertebral column (VC) defines the central axis of vertebrates. Among its malformations, adolescent idiopathic scoliosis (AIS) is most common, characterized by lateral spine curvature without congenital abnormalities. While etiology remains elusive, genetic studies in zebrafish have linked AIS to skeletogenesis, cilia structure, cerebrospinal fluid flow, and inflammation. In this study, we armc9 mutant, exhibiting AIS-like subcommissural organ, or Reissner fiber structure disruptions. We...
Since the Industrial Revolution, concentration of atmospheric carbon dioxide (CO 2 ) due to anthropogenic activities has increased at unprecedented rates. One-third CO emissions are dissolved in oceans affecting chemical equilibrium seawater, which turn leads a decrease pH and carbonate ion 3 2- concentration, phenomenon known as ocean acidification (OA). This disequilibrium can be detrimental marine organisms (e.g., mollusks) that fabricate mineralized structures based on calcium (CaCO )....
Pearls are highly prized biomineralized gemstones produced by molluscs. The appearance and mineralogy of cultured pearls can vary markedly, greatly affecting their commercial value. To begin to understand the role pearl sacs—organs that form in host oysters from explanted mantle tissues surround synthesize pearls—we undertook transcriptomic analyses identify genes differentially expressed sacs producing with different surface structural characteristics. Our results indicate gene expression...
Patients present a wide range of clinical severities in response severe acute respiratory syndrome coronavirus 2 infection, but the underlying molecular and cellular reasons why outcomes vary so greatly within population remains unknown. Here, we report that negative severely ill patients were associated with divergent RNA transcriptome profiles peripheral immune cells compared mild cases during first weeks after disease onset. Protein–protein interaction analysis indicated early-responding...
Patients present a wide range of clinical severities in response SARS-CoV-2 infection, but the underlying molecular and cellular reasons why outcomes vary so greatly within population remains unknown. Here, we report that negative severely ill patients were associated with divergent RNA transcriptome profiles peripheral immune cells compared mild cases during first weeks after disease onset. Protein-protein interaction analysis indicated early-responding cytotoxic NK an effective clearance...
Patients present a wide range of clinical severities in response SARS-CoV-2 infection, but the underlying molecular and cellular reasons why outcomes vary so greatly within population remains unknown. Here, we report that negative severely ill patients were associated with divergent RNA transcriptome profiles peripheral immune cells compared mild cases during first weeks after disease onset. Protein-protein interaction analysis indicated early-responding cytotoxic NK an effective clearance...
Abstract Terebriporidae is one of the four extant endolithic ctenostome bryozoan families, with colonies immersed into carbonate substrates like molluscan shells. This monogeneric family comprises 17 species, 11 and 6 fossil species. It currently considered closely related to vesicularioid ctenostomes, a group characterized by interconnected polymorphic stolons distinct gizzard as part their digestive systems. However, confusion persists regarding correct species identities affiliations many...
has emerged as a significant human pathogen, acquiring multiple antibiotic resistance genes, including carbapenemases. This study focuses on characterizing the plasmids harboring