A5037468258- Gold and Silver Nanoparticles Synthesis and Applications
- Antibiotics Pharmacokinetics and Efficacy
- Pesticide Residue Analysis and Safety
- Identification and Quantification in Food
- Spectroscopy Techniques in Biomedical and Chemical Research
- Biosensors and Analytical Detection
- Insect and Pesticide Research
- Analytical Chemistry and Chromatography
- Antimicrobial Peptides and Activities
- Spectroscopy and Chemometric Analyses
- Pharmaceutical and Antibiotic Environmental Impacts
- Traditional and Medicinal Uses of Annonaceae
- Electrochemical Analysis and Applications
- Diatoms and Algae Research
- Protein Hydrolysis and Bioactive Peptides
- Algal biology and biofuel production
- Analytical chemistry methods development
- Plant-derived Lignans Synthesis and Bioactivity
- Advanced biosensing and bioanalysis techniques
- Biochemical and Structural Characterization
- Meat and Animal Product Quality
- Pharmacological Effects and Assays
- Peptidase Inhibition and Analysis
- Chemical Synthesis and Analysis
- Animal Nutrition and Physiology
All-Russian State Scientific Research Institute for Control, Standardization and Certification of Veterinary Preparations
2018-2024
V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs
2023
Institute of Bioorganic Chemistry
2016-2018
Institute of Protein Research
2007
A novel chemical platform based on branched piperazine-2,5-dione derivatives (2,5-diketopiperazines) for creating orally available biologically active peptidomimetics has been developed. The includes a diketopiperazine scaffold with “built-in” functionally peptide fragments covalently attached via linkers. concept was applied to two hemostimulatory drugs, the dipeptide thymogen (GluTrp) and tripeptide stemokin (IleGluTrp). Preparation of series respective is described. Of five synthesized...
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A simple, rapid and sensitive surface enhanced Raman spectroscopy (SERS) method is described for the determination of fenbendazole (FBZ) residues in milk fermented dairy products using yogurt curd as examples. An extraction was used to purify samples from interfering components matrix. 5-Nitrothiabendazole, which has similar physicochemical properties, an internal standard. The detection limits were 1.8 nM, 8.8 nM yogurt, 13.5 curd. Using partial least squares (PLS), a calibration model...
The authors of the publication have described basic principles procedure defining metrological characteristics certified reference materials (hereinafter referred to as CRMs) antibacterial substances that are being developed. CRMs intended for certification measurement procedures and accuracy control results. can be used graduation, calibration measuring instruments if their technical comply with graduation instruments, well determination antibiotic sensitivity pathogenic microorganisms...
To date, antibiotics are often used in the treatment of infectious diseases medicine and veterinary medicine, as well growth promoters animal husbandry. The uncontrolled use leads to antibiotic residues food products that easily transmitted humans through chains. Due these undesirable effects, connection with circulation substandard counterfeit medicinal products, it is necessary control quality monitor safety by determining content drug using reference materials (RMs). aim this research was...
A B S T R C TA simple, rapid and sensitive SERS method is described for the quantitative determination of fenbendazole (FBZ) residues in milk fermented dairy products using yogurt curd as examples. An extraction was used to purify samples from interfering components matrix. 5-nitrothiabendazole, which has similar physicochemical properties, an internal standard. The detection limits were 1.8 nM, 8.8 nM yogurt, 13.5 curd. Using PLS method, a calibration model built concentration range 100...
In this article we proposed a method for quantitative determination of active substance in pharmaceuticals via Raman scattering using potassium ferricyanide as internal standard. We approved ketoprophenum drug veterinary use “Ketojekt”. The calculation metrological requirements procedures are established calibration. Either demonstrated the focalisation factor laser beam affects on reproducibility. provides precise, rapid, convenient to analysis that is more effective than standard HPLC assay.
The article represents data on adaptation and development of method for chlorophos analysis (active substance agent «Antiovod») in organs tissues calves cow milk by gas-liquid chromatography method. is based extraction from samples animal organs, tissues, acetone with addition 1% acetic acid solution, evaporation acetone-aqueous extract followed reextraction into chloroform, chloroform evaporation, dissolution residue using gasliquid chromatography. sensitivity the 0.005 mg/kg (or mg/l)....