Amardeep Awasthi

ORCID: 0000-0003-3237-9281
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Research Areas
  • Layered Double Hydroxides Synthesis and Applications
  • Synthesis and biological activity
  • Computational Drug Discovery Methods
  • Photochromic and Fluorescence Chemistry
  • Cancer therapeutics and mechanisms
  • Polyoxometalates: Synthesis and Applications
  • Supercapacitor Materials and Fabrication
  • Porphyrin and Phthalocyanine Chemistry
  • Advanced Nanomaterials in Catalysis
  • Catalysis and Hydrodesulfurization Studies
  • Catalytic Processes in Materials Science
  • Pharmacogenetics and Drug Metabolism
  • bioluminescence and chemiluminescence research
  • Nitric Oxide and Endothelin Effects
  • Nanomaterials for catalytic reactions
  • Chemical Synthesis and Analysis
  • Vanadium and Halogenation Chemistry
  • Nanocluster Synthesis and Applications
  • Oxidative Organic Chemistry Reactions
  • Porphyrin Metabolism and Disorders
  • Catalytic C–H Functionalization Methods
  • Long-Term Effects of COVID-19
  • Cancer Mechanisms and Therapy
  • Carbon dioxide utilization in catalysis
  • Metal-Catalyzed Oxygenation Mechanisms

Northwestern University
2023-2025

University of Delhi
1993-2023

It would be of great significance to introduce a new biocompatible Layered Double Hydroxide (LDH) for the efficient remediation wastewater. Herein, we designed facile, and environmental friendly layered double hydroxide NiFeTi very first time by hydrothermal route. The materialization LDH was confirmed FTIR, XRD Raman studies. BET results revealed high surface area (106 m2/g) morphological studies (FESEM TEM) portrayed sheets-like structure nanoparticles. material so obtained employed as an...

10.1038/s41598-019-52849-4 article EN cc-by Scientific Reports 2019-11-07

Coronavirus pandemic has caused a vast number of deaths worldwide. Thus creating an urgent need to develop effective counteragents against novel coronavirus disease (COVID-19). Many antiviral drugs have been repurposed for treatment but implicated minimal recovery, which further advanced the clearer insights and innovation derive therapeutics. Strategically, Noscapine, approved antitussive drug with positive effects on lung linings may show favorable outcomes synergistically in trials....

10.1080/07391102.2020.1808072 article EN Journal of Biomolecular Structure and Dynamics 2020-08-20

This work is generally focused on the synthesis of NiFeTi-layered double hydroxides (LDHs) using a hydrothermal route, which were calcined at various temperatures (varying from 200 to 600 °C). The synthesized materials physicochemically characterized. X-ray diffraction results revealed loss layered structure calcination resulting in formation oxides (LDOs) or mixed metal oxides, was also supported by Fourier transform infrared studies. Scanning electron microscopy show and creation LDOs...

10.1021/acsomega.0c01901 article EN publisher-specific-oa ACS Omega 2020-06-16

Background/Objectives: Interferon gamma (IFN-γ) in the melanoma tumor microenvironment plays opposing roles, orchestrating both pro-tumorigenic activity and anticancer immune responses. Our previous studies demonstrated role of neuronal nitric oxide synthase (nNOS) IFN-γ-stimulated progression. However, underlying mechanism has not been well defined. This study determined whether nNOS/NO COX-2/PGE2 signaling pathways crosstalk augment effects IFN-γ melanoma. Methods: Bioinformatic analysis...

10.3390/cancers17030477 article EN Cancers 2025-01-31

The enormous increase of heavy metal pollution has led to a rise in demand for synthesizing efficient and stable adsorbents its treatment. Therefore, we have designed novel adsorbent by introducing (MoS4)2- moieties within the layers NiFeTi LDH-NO3, via an ion exchange mechanism, as deal with increasing water due metals. Characterization techniques such XRD, FTIR, TGA, SEM, TEM, Raman spectroscopy were used confirm formation intercalated LDH structural changes after adsorption process....

10.1039/d0ra02766a article EN RSC Advances 2020-01-01

This work is mainly focused on the synthesis of an efficient and reusable heterogeneous Au/NiAlTi layered double hydroxide (LDH) nanocatalyst its applications in preparation biologically important xanthene, 1,4-dihydropyridine, polyhydroquinoline, 4H-pyran derivatives. NiAlTi LDH was designed hydrothermally then gold supported over surface by using ion-exchange NaBH4 reduction methods. The synthesized physicochemically characterized X-ray diffractrometry, Fourier-transform infrared...

10.1021/acsomega.0c03250 article EN publisher-specific-oa ACS Omega 2020-09-14

A series of potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors (hnNOS), based on a difluorobenzene ring linked to 2-aminopyridine scaffold with different functionalities at the 4-position, is reported. In our efforts develop novel nNOS for treatment neurodegenerative diseases, we discovered 17, which showed excellent potency toward both rat (Ki 15 nM) 19 nM), 1075-fold selectivity over eNOS 115-fold iNOS. 17 also permeability (Pe = 13.7 × 10–6 cm s–1),...

10.1021/acs.jmedchem.3c00782 article EN Journal of Medicinal Chemistry 2023-07-11

Antibiotic resistance is not only a global public health threat but also huge economic burden to our society that urgently needs be addressed by improved antibiotics and continuing development of novel molecules treat resistant bacterial infections. Nowadays combination therapies offer competent approach counteract antibiotic in bacteria. Better knowledge mechanisms has lead the finding new alternatives therapy. Hence, this article, we report series indoline derivatives their computational...

10.2174/1568026619666181129125524 article EN Current Topics in Medicinal Chemistry 2018-11-30

Lung cancer is the leading cause of deaths globally; 1 in 16 people are diagnosed with lung their lifetime. Microtubules, a critical cytoskeletal assembly, have an essential role cell division. Interference microtubule assembly leads to genetic instability during mitosis and death. Currently, available antimitotic drugs such as vincas taxanes limited due side effects alopecia, myelosuppression, drug resistance. Noscapine, opium alkaloid, tubulin-binding agent can alter causing Amino acids...

10.1021/acsptsci.2c00172 article EN ACS Pharmacology & Translational Science 2022-11-14

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199731145 article EN ChemInform 1997-07-29

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199552076 article EN ChemInform 1995-12-26

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199313210 article EN ChemInform 1993-03-30
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