A5103121561- Gastroesophageal reflux and treatments
- Neuroscience and Neuropharmacology Research
- Helicobacter pylori-related gastroenterology studies
- Esophageal and GI Pathology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Trace Elements in Health
- Electrochemical Analysis and Applications
- Eosinophilic Esophagitis
- Corneal Surgery and Treatments
- Cutaneous Melanoma Detection and Management
- Mitochondrial Function and Pathology
- Esophageal Cancer Research and Treatment
- Genetic factors in colorectal cancer
- Coordination Chemistry and Organometallics
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Metabolism and Genetic Disorders
- Phenothiazines and Benzothiazines Synthesis and Activities
- Folate and B Vitamins Research
- Aluminum toxicity and tolerance in plants and animals
- Epilepsy research and treatment
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Immunotherapy and Biomarkers
- Medical and Biological Ozone Research
- Pharmacological Effects and Toxicity Studies
Universitätsklinikum Erlangen
2020
Friedrich-Alexander-Universität Erlangen-Nürnberg
2020
Kresge Eye Institute
2011
Wayne State University
2011
Dartmouth–Hitchcock Medical Center
2006-2007
White River Junction VA Medical Center
2006-2007
University of Vienna
1972-1979
Abstract Background In recent years, monoclonal antibodies such as ipilimumab, nivolumab, and pembrolizumab have made a significant impact on the treatment of advanced melanoma. Combination immune checkpoint inhibitors leads to improved survival response rates 58%‐61% compared monotherapy (36%‐44%). However, price for better is also higher frequency severe adverse events (59%) (17%‐21%). This study examines attitudes towards melanoma therapy options physicians, healthy individuals, patients,...
Hintergrund: Die in jüngster Zeit verfügbaren genetischen Analysen haben die Mängel der herkömmlichen phänotypischen Methode zur Klassifikation von Hornhautdystrophien (HD) aufgezeigt. Anomalien verschiedenen Genen können einen einzigen Phänotyp verursachen, wogegen verschiedene Defekte einem Gen Phänotypen bedingen können. Einige als korneale Dystrophien bezeichnete Störungen scheinen keinen Hintergrund zu haben. Absicht: Ziel dieser Studie war es, ein neues System Klassifizierung...
Purpose: The Bravo capsule is commonly ordered to evaluate patients (Pts) with acid reflux symptoms. Despite its widespread use, the clinical utility of has not been prospectively examined. Methods: Before placing capsule, referring physicians (GIs, surgeons, primary care) completed a questionnaire requesting: indications for test (primary and secondary); symptoms secondary; duration); prior testing problem; medication use. Demographic information was obtained. Patients were studied either...
6071 Background: Individuals >80 years represent a growing proportion of colon cancer patients and create decision-making challenge for surgeons due to frequent comorbidities. Our objective was describe patterns surgery in examine outcomes with without colectomy. Methods: Medicare beneficiaries diagnosed from 1992-2005 were identified the Surveillance, Epidemiology, End Results-Medicare database; stage IV excluded. χ2 two-way ANOVA assessed differences patient characteristics. Kaplan-Meier...
Purpose: The Bravo capsule is widely used to evaluate patients (Pts) with acid reflux symptoms. A preliminary study (Dukowicz et al. Am J Gastroenterol 2006; 101(9) Suppl:S48) appears show it be clinically useful. Our aim was prospectively the clinical utility of in a large series Pts by determining whether changes diagnosis, provides new information, or alters management. Methods: Prior deployment, referring physicians completed questionnaire requesting: indications for test; symptoms;...
Purpose: Background: Fats are associated with increased GER and CCK (cholecystokinin) is thought to play a role. The contribution of other nutrients not well described. Aims: Evaluate the effects intraduodenal nutrient infusion on serum levels, lower esophageal sphincter (LES) pressure, GER. Methods: 24 healthy asymptomatic Caucasian volunteers were studied. A water-perfused, 6 cm Dent sleeve catheter (Dentsleeve International Ltd) was positioned across LES fluoroscopically; an port located...
Parkinsonism was induced in rats by using phenothiazines (Butyrylperazin and Thioproperazin). (P-group), or reserpine, (R-group). [U-14 C)D-glucose administered when the symptoms of had become fully developed. Concentrations radioactivities different metabolites were studied brain, liver blood serum. 1. Both types treatments resulted a decrease synthesis amino acids from [14C]glucose brain. The concentrations glycogen remained uneffected. Phenothiazines enhanced conversion lipids, while...
Purpose: Acid reflux is a common occurrence in children. pH testing frequently used to evaluate the role that acid plays symptom generation. The safety and utility of Bravo capsule has not previously been evaluated pediatric population. Methods: Consecutive patients referred for placement were enrolled this study. Demographic information, symptoms, medication use recorded. was performed either conjunction with upper endoscopy or unsedated motility laboratory after esophageal manometry. At...