William H. Chapman

ORCID: 0000-0003-3247-4772
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About
Contact & Profiles
Research Areas
  • Bariatric Surgery and Outcomes
  • Genetics and Plant Breeding
  • Diet and metabolism studies
  • Effects of Radiation Exposure
  • Body Contouring and Surgery
  • Diabetes Treatment and Management
  • Gastric Cancer Management and Outcomes
  • Photochemistry and Electron Transfer Studies
  • Hernia repair and management
  • Cardiac and Coronary Surgery Techniques
  • Synthesis and Reactions of Organic Compounds
  • Crop Yield and Soil Fertility
  • Radiation Effects and Dosimetry
  • Radical Photochemical Reactions
  • Cardiac Valve Diseases and Treatments
  • Sulfur Compounds in Biology
  • Wheat and Barley Genetics and Pathology
  • Glutathione Transferases and Polymorphisms
  • Congenital Diaphragmatic Hernia Studies
  • 3D Surveying and Cultural Heritage
  • Adipose Tissue and Metabolism
  • Radioactive contamination and transfer
  • Vitamin C and Antioxidants Research
  • Remote Sensing and LiDAR Applications
  • Geological Modeling and Analysis

De Montfort University
2021

New Mexico State University
2019

John Wiley & Sons (United States)
2019

East Carolina University
2006-2016

Columbia University
1996-2015

Dartmouth–Hitchcock Medical Center
2014

Philadelphia University
2013

RELX Group (United States)
2013

Greenville College
1997-2012

Winston-Salem State University
2011

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelective Hydrolysis of Phosphate Esters, Nitrophenyl Phosphates and UpU, by Dimeric Zinc Complexes Depends on the Spacer LengthWilliam H. Chapman Jr. Ronald BreslowCite this: J. Am. Chem. Soc. 1995, 117, 20, 5462–5469Publication Date (Print):May 1, 1995Publication History Published online1 May 2002Published inissue 1 1995https://pubs.acs.org/doi/10.1021/ja00125a005https://doi.org/10.1021/ja00125a005research-articleACS PublicationsRequest reuse...

10.1021/ja00125a005 article EN Journal of the American Chemical Society 1995-05-01

Obesity is associated with a decrement in the ability of skeletal muscle to oxidize lipid. The purpose this investigation was determine whether clinical interventions (weight loss, exercise training) could reverse impairment fatty acid oxidation (FAO) evident extremely obese individuals. FAO assessed by incubating homogenates [1-(14)C]palmitate and measuring (14)CO(2) production. Weight loss studied using both cross-sectional longitudinal designs. Muscle women who had lost weight (decrease...

10.1152/ajpendo.00354.2007 article EN AJP Endocrinology and Metabolism 2008-02-06

Roux-en-Y gastric bypass (RYGB) has been shown to induce rapid and durable reversal of type 2 diabetes.The aim the study was investigate a possible mechanism for remission diabetes after RYGB.A cross-sectional, nonrandomized, controlled conducted. Surgery patients were studied before RYGB 1 wk 3 months surgery.This conducted at East Carolina University.Subjects recruited into three groups: 1) lean controls with no surgery [body mass index (BMI) < 25 kg/m²; n = 9], 2) severely obese diabetic...

10.1210/jc.2011-0165 article EN The Journal of Clinical Endocrinology & Metabolism 2011-05-19

Surgical treatments of obesity have been shown to induce rapid and prolonged improvements in insulin sensitivity.The aim the study was investigate effects gastric bypass surgery mechanisms that explain improvement sensitivity.We performed a cross-sectional, nonrandomized, controlled study.This conducted jointly between Departments Exercise Science Physiology at East Carolina University Greenville, North Carolina.Subjects were recruited into four groups: 1) lean [body mass index (BMI) < 25...

10.1210/jc.2008-1030 article EN The Journal of Clinical Endocrinology & Metabolism 2008-09-03

Glutathione injection prior to irradiation improves the survival rate, decreases weight loss, and reduces susceptibility trauma of X-irradiated mice. Four mg glutathione per g mouse is roughly twice as effective 1.6 mouse. In these experiments no protection was evident in low lethal dose range (450-650 r).

10.3181/00379727-75-18185 article EN Experimental Biology and Medicine 1950-11-01

Total body exposure to ionizing radiations results in widespread cellular damage which is manifest by the promptly ensuing “toxemia” known as radiation illness. The has past been considered largely due (a) protein denaturation and (b) formation of “toxic products.” These concepts resulted various forms symptomatic replacement therapy for Recent reports have stimulated new investigative therapeutic endeavor this field calling attention effects produced ionization products irradiated water on...

10.1148/55.6.865 article EN Radiology 1950-12-01

1. By the criteria used there is no significant difference in destructive effects of irradiation on normal mice or treated with large doses glutathione before irradiation. 2. A striking seen rate regeneration hemopoietic tissues.

10.3181/00379727-76-18502 article EN Experimental Biology and Medicine 1951-02-01
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