Syril Dorairaj

ORCID: 0000-0003-3251-4826
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About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Corneal surgery and disorders
  • Retinal Diseases and Treatments
  • Intraocular Surgery and Lenses
  • Retinal Imaging and Analysis
  • Optical Coherence Tomography Applications
  • Ophthalmology and Eye Disorders
  • Retinal and Macular Surgery
  • Cerebral Venous Sinus Thrombosis
  • Retinal and Optic Conditions
  • Ocular Surface and Contact Lens
  • Proteoglycans and glycosaminoglycans research
  • Retinal Development and Disorders
  • Ergonomics and Musculoskeletal Disorders
  • Ocular Infections and Treatments
  • Ophthalmology and Visual Impairment Studies
  • Ocular Diseases and Behçet’s Syndrome
  • Ocular Oncology and Treatments
  • Traumatic Ocular and Foreign Body Injuries
  • Retinopathy of Prematurity Studies
  • Sympathectomy and Hyperhidrosis Treatments
  • Ophthalmology and Visual Health Research
  • Corneal Surgery and Treatments
  • Visual perception and processing mechanisms
  • Vascular Malformations Diagnosis and Treatment

Mayo Clinic in Florida
2016-2025

WinnMed
2016-2025

Jacksonville College
2015-2024

Tan Tock Seng Hospital
2024

Glaucoma Associates of Texas
2022

Creative Commons
2022

Mayo Clinic
2013-2021

New World Medical (United States)
2017-2020

University of Illinois Chicago
2017

Yale University
2015

To describe the 12-month efficacy and safety of goniotomy performed using Kahook Dual Blade (KDB) in combination with cataract surgery eyes medically treated open-angle glaucoma (OAG). This was a prospective, interventional case series conducted at seven centers North America. Consecutive patients OAG visually significant underwent phacoemulsification combined (PE + goniotomy) KDB. Indications for included reduction intraocular pressure (IOP) IOP-lowering medications. De-identified data were...

10.1007/s12325-018-0755-4 article EN cc-by-nc Advances in Therapy 2018-08-04

To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of a single-use dual blade (Kahook) in patients with mild to end-stage glaucoma.International multicenter ophthalmic care centers.Prospective interventional case series.Consecutive glaucoma who had phacoemulsification plus goniotomy were enrolled this study. Each center collected deidentified clinical data, including preoperative postoperative IOP, medication use, adverse events, whether additional surgery was required...

10.1016/j.jcrs.2017.06.046 article EN cc-by-nc-nd Journal of Cataract & Refractive Surgery 2017-09-01

The purpose of the study is to describe short-term efficacy and safety goniotomy with trabecular meshwork excision using Kahook Dual Blade (KDB, New World Medical Inc., Rancho Cucamonga, CA) in patients severe or refractory glaucoma.Retrospective multicentric case series 53 eyes glaucoma as defined by ICD-10 conducted United States, Mexico, Switzerland. Primary outcome was a ≥20% decrease intraocular pressure (IOP) from baseline at 6 months. Secondary measures were probability achieving an...

10.1097/ijg.0000000000001019 article EN Journal of Glaucoma 2018-07-04

This study is the first to report micropulse transscleral cyclophotocoagulation (MP-TSCPC) use in only good vision patients. MP-TSCPC significantly reduced intraocular pressure (IOP) and glaucoma medication without any significant reduction visual acuity at every postoperative follow-up point.To evaluate outcomes of eyes with baseline best-corrected (BCVA) ≥20/60.A retrospective review patients who underwent Mayo Clinic Ross Eye Institute from July 2016 August 2017 BCVA ≥20/60, a minimum 3...

10.1097/ijg.0000000000001339 article EN Journal of Glaucoma 2019-08-02

To describe the use of anterior segment optical coherence tomography (OCT) in studying dynamic dark-light changes chamber angle.Thirty-seven normal subjects with open angles on dark-room gonioscopy and 18 narrow were analyzed. The anterior-chamber angle captured real-time video recording. opening distance (AOD500) trabecular iris space area (TISA500) nasal pupil diameter each representative serial images measured. Linear regression analysis was performed to investigate association between...

10.1167/iovs.07-0010 article EN Investigative Ophthalmology & Visual Science 2007-08-27

To compare anterior segment parameters between eyes of Chinese and Caucasians using optical coherence tomography to evaluate the association these chamber angle width two ethnic groups.60 60 Caucasians, 30 with open angles narrow (defined as Shaffer grade < or =2 in > =3 quadrants during dark room gonioscopy) each group, were consecutively enrolled. One eye subject was randomly selected for imaging a completely darkened room. Measurements, including depth (ACD), scleral spur-to-scleral spur...

10.1136/bjo.2009.167296 article EN British Journal of Ophthalmology 2010-07-07

To compare the visual outcomes and complications after suture-assisted fibrin glue-assisted scleral fixated intraocular (IOL) implantation.Scleral IOL implantation was performed in patients with inadequate capsular support. Intraocular lens fixation achieved using sutures or glue. Main parameters evaluated were complications.Fifty included study (n=25 suture, n=25 glue). The most common indication for cataract surgery complicated posterior capsule rupture (29/50 [58%]). No significant...

10.3928/1081597x-20120221-01 article EN Journal of Refractive Surgery 2012-03-05

A multicenter retrospective comparison of goniotomy versus trabecular bypass device implantation in glaucoma patients undergoing cataract extraction Syril K Dorairaj,1 Malik Y Kahook,2 Blake Williamson,3 Leonard Seibold,4 Mohammed ElMallah,5 Inder P Singh6 On behalf the KDB Goniotomy Study Group 1Department Ophthalmology, Mayo Clinic, Jacksonville, FL, 2School Medicine, University Colorado, Denver, CO, 3Williamson Eye Center, Baton Rouge, LA, 4School Aurora, 5Ocala Eye, Ocala, 6The Center...

10.2147/opth.s158403 article EN cc-by-nc Clinical ophthalmology 2018-04-01

To characterize the reduction in intraocular pressure (IOP) and IOP-lowering medication use following goniotomy via trabecular meshwork excision performed using Kahook Dual Blade as a stand-alone procedure adult eyes with glaucoma uncontrolled on regimen of 1–3 topical medications. In this retrospective analysis, data from consecutive patients undergoing by 11 surgeons were analyzed. Preoperative, intraoperative, postoperative follow-up through 6 months collected. The primary efficacy...

10.1007/s12325-018-0803-0 article EN cc-by-nc Advances in Therapy 2018-10-13

To compare the efficacy and safety of combined cataract extraction either excisional goniotomy performed with Kahook Dual Blade (KDB; phaco-KDB group) or single iStent trabecular bypass implantation (phaco-iStent in eyes mild to moderate glaucoma visually significant cataract. This was a retrospective analysis 315 from 230 adults treated one more intraocular pressure (IOP)-lowering medications (190 134 subjects group 125 96 phaco-iStent that required no subsequent surgical intervention for...

10.1007/s12325-019-01025-1 article EN cc-by-nc Advances in Therapy 2019-07-17

To evaluate dynamic changes in iris configuration and their association with anterior chamber angle width by using segment optical coherence tomography (ASOCT).Forty-six normal subjects open angles 40 narrow (Shaffer grade < or =2 three more quadrants during dark room gonioscopy) were analyzed. The ASOCT dark-light of bowing captured real-time video recording nasal bowing, angle, pupil diameter measured serial image frames selected from the capture. associations between thickness, depth...

10.1167/iovs.09-3941 article EN Investigative Ophthalmology & Visual Science 2010-03-17

To determine the prevalence and etiology of amblyopia in school children.A total 4020 children aged between 5 15 years were screened a population-based, cross-sectional study. Best corrected visual acuity detailed ophthalmic evaluation performed all participants. Amblyopia associated with degraded input due to high refractive error was labeled ametropic amblyopia. Anisometropic diagnosed participants interocular difference ≥1 diopter. Strabismic included that conflicting inputs eyes squint....

10.3109/09286586.2013.809772 article EN Ophthalmic Epidemiology 2013-07-18

To analyze the most common neurophthalmological conditions that may mimic glaucomatous optic neuropathy and to determine which often lead misdiagnosis when evaluated by a glaucoma specialist. We reviewed charts of consecutive patients with neuropathies caused screened in single Eye Clinic within period 24 months. Within these enrolled patients, we selected eyes whose fundoscopic appearance could resemble based pre-defined criteria (vertical cup-to-disc ratio ≥0.6, asymmetry ≥0.2 between...

10.1186/s12886-016-0395-x article EN cc-by BMC Ophthalmology 2017-01-10

The purpose of this study was to characterize reductions in intraocular pressure (IOP) and the need for IOP-lowering medications following phacoemulsification combined with Kahook Dual Blade-assisted goniosynechialysis excisional goniotomy eyes angle-closure glaucoma cataract.In retrospective, interventional case series, preoperative, operative, postoperative data were collected through 6 months follow-up from 42 24 subjects. Outcomes included mean IOP reduction, reduction medications,...

10.1097/ijg.0000000000001256 article EN Journal of Glaucoma 2019-04-11

To compare reduction in intraocular pressure (IOP) and IOP-lowering medication eyes undergoing excisional goniotomy with Kahook Dual Blade (KDB) vs iStent microbypass implantation, both combined phacoemulsification, mild to moderate open-angle glaucoma (OAG).Nine practices the United States.Prospective, randomized, active-controlled, parallel-group clinical trial.Eyes were randomized KDB-Phaco or iStent-Phaco group. Demographics, corrected distance visual acuity, IOP, medications, adverse...

10.1097/j.jcrs.0000000000000229 article EN Journal of Cataract & Refractive Surgery 2020-04-30

<h3>Objective</h3> To assess the agreement between findings obtained at dark-room gonioscopy and ultrasound biomicroscopy (UBM) in diagnosis of iridotrabecular apposition light dark conditions. <h3>Methods</h3> We enrolled patients with appositional angle closure performed using a 1-mm slitlamp beam that did not cross pupil. Ultrasound biomicroscopic images were acquired normal room subsequently all lights off. Images evaluated for presence or absence iris-cornea contact. The opening...

10.1001/archopht.125.10.1331 article EN Archives of Ophthalmology 2007-10-01

To determine the prevalence and etiology of childhood blindness in a rural population southern India through based study.A cross sectional, house-to-house survey to screen for included 14,423 children < 16 years. Blindness was defined as best corrected visual acuity 3/60 better eye. The first stage screening done by interns under supervision ophthalmology residents. Senior residents examined referred cases from stage. Those detected be blind were brought tertiary care hospital detailed...

10.1080/09286580801977668 article EN Ophthalmic Epidemiology 2008-01-01

Abstract Background To investigate anatomical configuration of ciliary body and iris using ultrasound biomicroscopy as a predictor malignant glaucoma development. Design Retrospective study in tertiary care hospital. Participants Cohort 31 consecutive patients diagnosed with post‐surgical glaucoma. Methods Anterior chamber angle, involved eyes that had evaluation prior to the onset were evaluated. In cases no presurgical exam eye, images from fellow eye (imaged within 6 months) analysed....

10.1111/ceo.12057 article EN Clinical and Experimental Ophthalmology 2012-12-25

Purpose: The aim of this study was to describe changes in intraocular pressure (IOP) and IOP medications after phacoemulsification with Kahook Dual Blade-assisted goniosynechialysis excisional goniotomy eyes angle-closure glaucoma cataract. Design: Retrospective case series. Methods: Data were collected retrospectively through 24 months follow-up 42 subjects. Results: Preoperative mean (SE) 25.5 (0.7) mm Hg using a 2.3 (0.1) per eye. At month 24, had decreased 13.5 (0.4) [a reduction 12.0...

10.1097/apo.0000000000000321 article EN cc-by-nc-nd Asia-Pacific Journal of Ophthalmology 2021-01-20

Purpose.: To compare macular pigment optical density (MPOD) in type 2 diabetic and nondiabetic patients by using dual-wavelength autofluorescence imaging to investigate the correlation of MPOD with glycosylated hemoglobin (HbA1C) serum lipid levels. Methods.: Forty-three were divided into groups 1 (controls, n = 14), (diabetic without retinopathy, 17), 3 mild nonproliferative 12). was measured a modified confocal scanning laser ophthalmoscope compared among (analysis variance). The HbA1C...

10.1167/iovs.09-4695 article EN Investigative Ophthalmology & Visual Science 2010-05-26
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