Machiel J. Zwarts

ORCID: 0000-0003-3254-5438
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About
Contact & Profiles
Research Areas
  • Muscle activation and electromyography studies
  • Genetic Neurodegenerative Diseases
  • Neurogenetic and Muscular Disorders Research
  • Muscle Physiology and Disorders
  • Amyotrophic Lateral Sclerosis Research
  • Peripheral Nerve Disorders
  • Neuroscience and Neural Engineering
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Transcranial Magnetic Stimulation Studies
  • Motor Control and Adaptation
  • Advanced Sensor and Energy Harvesting Materials
  • Botulinum Toxin and Related Neurological Disorders
  • Ion channel regulation and function
  • EEG and Brain-Computer Interfaces
  • Epilepsy research and treatment
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Cardiomyopathy and Myosin Studies
  • Cerebral Palsy and Movement Disorders
  • Stroke Rehabilitation and Recovery
  • Hereditary Neurological Disorders
  • Nerve Injury and Rehabilitation
  • Musculoskeletal pain and rehabilitation
  • Orthopedic Surgery and Rehabilitation
  • Inflammatory Myopathies and Dermatomyositis

Kempenhaeghe
2010-2021

Maastricht University Medical Centre
2014-2019

Maastricht University
2019

Radboud University Nijmegen
2005-2015

Radboud University Medical Center
2005-2015

E Ink (South Korea)
2009

Vrije Universiteit Amsterdam
2007-2008

Dutch Institute for Fundamental Energy Research
2000-2007

Erasmus MC
2004

Erasmus University Rotterdam
2004

Abstract Ultrasonography can detect structural muscle changes caused by neuromuscular disease. Quantitative analysis is the preferred method to determine if ultrasound findings are within normal limits, but normative data incomplete. The purpose of this study was provide ultrasonography for thickness and echo intensity five different groups in adults. Bilateral scans sternocleidomastoid, biceps brachii/brachialis, forearm flexor group, quadriceps femoris, tibialis anterior were made 95...

10.1002/mus.21458 article EN Muscle & Nerve 2009-08-31

The purpose of this study was to establish normal values muscle thickness, ratio thickness subcutaneous fat and echo intensity in children between 11 weeks 16 years age. Transverse scans four muscles were made by standardized real-time ultrasound examination. digitized, mean measured using gray-scale analysis. A multiple regression equation used which independent parameter (age, height, weight, or sex) influenced the variables for each muscle. Muscle depended on child's weight. other...

10.1002/mus.10384 article EN Muscle & Nerve 2003-04-09

Abstract Background Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans of elderly people related to vascular risk factors cognitive motor impairment, ultimately leading dementia or parkinsonism in some. In general, the relations are weak, not all subjects with SVD become demented get parkinsonism. This might be explained by diversity underlying pathology both white matter lesions (WML) normal appearing (NAWM). Both cannot properly appreciated conventional MRI....

10.1186/1471-2377-11-29 article EN cc-by BMC Neurology 2011-02-28

Ehlers-Danlos syndrome (EDS) is a clinically and genetically heterogeneous group of heritable connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, fragility. Muscle involvement plausible based on recently discovered interactions between muscle cells extracellular matrix molecules; however, symptoms are only sporadically reported. We designed cross-sectional study to find out whether neuromuscular features part EDS.Standardized questionnaires, physical...

10.1002/ana.21643 article EN Annals of Neurology 2009-03-19

Different methods of measuring human muscle fiber conduction velocity (MFCV) are outlined. A major division can be made between invasive (needle) and noninvasive [surface electromyographic (EMG)] recording techniques. The benefits limitations associated with the different approaches discussed. individual fibers measurable needle recordings on routine EMG apparatus. Velocities measured electrical stimulation single or bundle in general lower than during voluntary contraction. With surface...

10.1097/00004691-198904000-00004 article EN Journal of Clinical Neurophysiology 1989-04-01

To obtain more insight into the changes in mean muscle fiber conduction velocity (MFCV) during sustained isometric exercise at relatively low contraction levels, we performed an in-depth study of human tibialis anterior by using multichannel surface electromyogram. The results show increase MFCV after initial decrease 30 or 40% maximum voluntary all five subjects studied. With a peak analysis, calculated distribution velocities action potentials bipolar electromyogram signal. It shows two...

10.1152/japplphysiol.00665.2002 article EN Journal of Applied Physiology 2003-09-01

Objective. The primary aim of this study was to compare the predictive value motor evoked potentials (MEPs) and early clinical assessment with regard long-term hand recovery in patients profound hemiplegia after stroke. Methods. sample an inception cohort 39 stroke acute, ischemic, supratentorial initial upper-extremity paralysis admitted academic hospital. Hand function defined at 26 weeks poststroke as a Fugl–Meyer Motor Assessment (FMA) score >3 points. following prognostic factors...

10.1177/1545968308317578 article EN Neurorehabilitation and neural repair 2008-09-15

Abstract Muscle ultrasound is a useful technique to detect neuromuscular disorders. Quantification of muscle echo intensity (EI) using gray‐scale analysis more reliable and sensitive compared with visual evaluation the images. We devised method reliably use EI normal values established one device for another device. Based on measurements in dedicated phantom 7 healthy subjects, conversion equation was calculated convert mean EI. The reliability this next evaluated follow‐up study 22...

10.1002/mus.21285 article EN Muscle & Nerve 2009-03-19
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