- Muscle metabolism and nutrition
- Alcohol Consumption and Health Effects
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Clinical Nutrition and Gastroenterology
- Metabolism and Genetic Disorders
- Liver Disease Diagnosis and Treatment
- Nutrition, Genetics, and Disease
- Antioxidant Activity and Oxidative Stress
- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Alcoholism and Thiamine Deficiency
- Diet, Metabolism, and Disease
- Vitamin C and Antioxidants Research
- Mitochondrial Function and Pathology
- Biochemical effects in animals
- Exercise and Physiological Responses
- Muscle Physiology and Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Child Nutrition and Feeding Issues
- Eicosanoids and Hypertension Pharmacology
- Genetic Neurodegenerative Diseases
- Cardiac electrophysiology and arrhythmias
- Tea Polyphenols and Effects
King's College London
2014-2023
King's College Hospital
1989-2023
King's College School
1994-2014
Genomics (United Kingdom)
2013
University of Arizona
2007-2008
University of Nottingham
2008
University of Central Lancashire
2008
University of Reading
2008
St Thomas' Hospital
2008
Hizen Psychiatric Center
2002-2007
A rapid procedure for measuring the specific radioactivity of phenylalanine in tissues was developed. This facilitates accurate determination rates protein synthesis a wide range by injection 150 mumol L-[4-(3)H]phenylalanine/100 g body wt. The large dose amino acid results rise free to values close that plasma, followed slow but linear fall. enables rate be calculated from measurements and protein-bound during 10 min period after radioisotope.
1. Insulin was infused into young male rats in the postabsorptive state. Rates of protein synthesis skeletal muscle were determined during final 10 min infusion from incorporation label after intravenous injection a massive dose [3H]phenylalanine. not altered first insulin infusion, but increased significantly between and 60 min. 2. Rats with different amounts for 30 When concentrations to 40 microunits/ml plasma there no change synthesis, higher than 70 caused significant stimulation....
Polyphenols contained within plant tissues are consumed in significant amounts the human diet and known to influence a number of biological processes. This study investigated effects an anthocyanin-rich berry-extract on glucose uptake by intestinal Caco-2 cells. Acute exposure (15 min) berry extract (0.125%, w/v) significantly decreased both sodium-dependent (Total uptake) sodium-independent (facilitated ³H-D-glucose uptake. In longer-term studies, SGLT1 mRNA GLUT2 expression were reduced...