A5038066899- Advanced biosensing and bioanalysis techniques
- Force Microscopy Techniques and Applications
- Nanopore and Nanochannel Transport Studies
- Electrostatics and Colloid Interactions
- Lubricants and Their Additives
- Adhesion, Friction, and Surface Interactions
- RNA Interference and Gene Delivery
- Supramolecular Self-Assembly in Materials
- Material Dynamics and Properties
- Lipid Membrane Structure and Behavior
- RNA Research and Splicing
- Fluid Dynamics and Thin Films
- Gold and Silver Nanoparticles Synthesis and Applications
- Granular flow and fluidized beds
- Surfactants and Colloidal Systems
- Surface Modification and Superhydrophobicity
- Electrohydrodynamics and Fluid Dynamics
- Microfluidic and Bio-sensing Technologies
- Advanced Battery Technologies Research
- Brake Systems and Friction Analysis
- Membrane-based Ion Separation Techniques
- Bacteriophages and microbial interactions
- Fuel Cells and Related Materials
Institut Charles Sadron
2008-2024
Centre National de la Recherche Scientifique
2001-2024
Université de Strasbourg
2013-2024
University of Cambridge
2008
Institute for Atomic and Molecular Physics
2007-2008
University of Amsterdam
2008
Collège de France
2005-2006
Laboratoire de Dynamique des Fluides
2003
Laboratoire de Réactivité de Surface
2001
Using total internal reflection-fluorescence recovery after photobleaching, the local velocity, averaged over distances of 50 nm from solid wall, has been measured for two different simple liquids, squalane and hexadecane, sheared on three smooth surfaces with similar roughness but gradually decreasing fluid-solid interactions. We show that not only strength interactions, also shape molecules fluid deeply affect friction degree slip at wall.
It is commonly acknowledged that roughness decreases the aptitude of simple liquids to exhibit flow with slip at solid interfaces. Most available studies have, however, been conducted on substrates for which both surface chemistry and were varied simultaneously, making it difficult identify their respective role wall slip. To overcome this difficulty, we have developed a series surfaces formed by grafting hyperbranched polymeric nanoparticles smooth, dense, self-assembled monolayer...
We report an experimental study in which we compare the self-assembly of 1 μm colloids bridged through hybridization complementary single-stranded DNA (ssDNA) strands (12 bp) attached to variable-length double-stranded spacers that are grafted colloids. considered three different spacer lengths: long (48 500 bp), intermediate length (7500 and no (in case ssDNA were directly colloids). In all cases, same pairs used. However, confocal microscopy revealed aggregation behavior is very different....
We studied the aggregation of 1 µm colloids bridged by DNA with 32 contour length. mixed two species particles grafted double-stranded λ-DNA displaying short, complementary single-stranded 'overhangs' as free binding-ends. Confocal microscopy showed formation stable, size-limited clusters in which were at touching contact. Simulations suggest that observed close contact and limitation to grow both result from entropic exclusion bridging space between nearby particle surfaces.
Abstract Although cationic cell-penetrating peptides (CPPs) are able to bind cell membranes, thus promoting internalization by active pathways, attachment of cargo molecules CPPs invariably reduces their cellular uptake. We show here that CPP binding lipid bilayers, a simple model the membrane, can be recovered designing self-assemble into spherical micelles and increase local interfacial density on surface cargo. Experiments performed giant unilamellar vesicles under confocal laser scanning...
We have adsorbed plasmid pUc19 DNA on a supported bilayer. By varying the fraction of cationic lipids in membrane, we tuned surface charge. Plasmid conformations were imaged by Atomic Force Microscopy (AFM). performed two sets experiments: deposition from salt free solution charged bilayers and salty solutions neutral bilayers. Both show similar trends: at low charge density or bulk concentration, internal electrostatic repulsion forces plasmids to adopt completely opened structures, while...
Inspired by recent atomic force microscope (AFM) images of plasmids deposited on oppositely charged supported lipid bilayers from salt free solution, we propose a model for strongly adsorbed supercoiled cyclic stiff polyelectrolytes. We discuss how the excess linking number Lk cycle is shared between writhe Wr and twist Tw at equilibrium obtain typical self-crossings in as function surface charge density. The crossings simply determined crossing penalty which local quantity number. well...
We have adsorbed plasmid PuC19 DNA on a supported bilayer. The mobility of the lipids within bilayer ensured 2D equilibrium molecule. By varying fraction cationic in membrane, we tuned surface charge. Plasmids conformations were imaged by Atomic Force Microscopy (AFM).We performed two sets experiments: deposition from salt free solution charged bilayers and salty solutions neutral bilayers. can be seen as rings, completely opened structures, or tightly supercoiled plectonemes, depending...