Amyloid fibril-based ultralow-density aerogels are designed by functionalization with gold nanoparticles and microcrystals, leading to hybrids of unprecedented lightness functionality. By changing the colloidal shape, size, concentration, composition can be tuned reach contents ≥20 kt equivalent, yet at densities ≈103 lighter than any equivalent alloys, combining unique features such as porosity, catalytic properties, pressure sensing, autofluorescence. As a service our authors readers, this...

Through a straightforward approach, new meltable, halogen-free, nitrogen-phosphorus-based flame retardant (FR), 6-(2-(4,6-diamino-1,3,5-triazin-2-yl)ethyl) dibenzo[c,e][1,2]oxaphosphinine 6-oxide (DTE-DOPO) was synthesized and incorporated in polyamide 6 (PA6). It proved that very low phosphorus content of 1.46 wt% for DTE-DOPO additive improved the retardancy PA6, leading to non-flammable material. The performance compared commercially-available Exolit® OP 1230. PA6 formulations were...

Abstract This feature article covers the recent developments of amyloid fibrils as templates for organic–inorganic hybrid aerogels. It aims at introducing reader to fibril functional bio‐nanomaterials and show how, building on prior art colloidal aerogels, these anisotropic colloids can be used template inorganic particles form gels Specifically, templated gold, silver, calcium aerogels are discussed focusing their material synthesis how preparation conditions tuned vary final materials'...

Amyloid fibrils are charged semiflexible assemblies with very large aspect ratio (length to diameter, L/D). Because of this ratio, the isotropic (I) and nematic (N) phase coexistence expected from first-order thermodynamic nature I–N transition, as predicted Onsager's theory, is vanishingly small and, in practice, challenging experimentally observe. In study we present a remarkable widening I + N biphasic region β-lactoglobulin suspension via freeze–thaw (F–T) cycling. The demixing behavior...

Abstract The use of oleoresin as natural colorant is widely used in daily food and beverages. However, there still a lack information about the solid–liquid extraction process to obtain this oily extract from sweet paprika. effects different operating variables, such technique, temperature, powder‐to‐solvent ratio type solvent on extraction, were investigated through experiments leaching was theoretically modeled. results indicated that although yields are not affected by ultrasound‐assisted...

The feasibility of producing pharmaceutical co-crystals by simultaneous high pressure homogenization (HPH) solid API and co-former has been investigated using as model the co-crystal forming system represented theophylline (TPL) saccharin (SAC). First, thermodynamic aspects this process have clarified investigating ternary TPL – SAC water, particularly constructing its phase diagram measuring representative points solubility in water at temperatures between 15 35 °C. In a second step,...

After reviewing several techniques for solid-state deracemisation, we study the deracemisation of two drug precursors with different techniques.

Poly(3-hydroxybutyrate) (P3HB) is a thermoplastic, biocompatible, and truly biodegradable polyester produced by bacteria characterized high degree of crystallinity due to its isotactic nature. In order tackle the challenges processability at time developing new green materials, use additives highly recommended. this work, biocompatible semicrystalline multiblock copolyester poly(butylene succinate-butylene dilinoleate) (PBS:DLA), shortly abbreviated as CoPo, used produce P3HB blends. The...

The formulation of poorly water-soluble active pharmaceutical ingredients (APIs) has been widely studied in the last few decades to overcome limited bioavailability imposed by these ingredients. In this work, supercritical fluid extraction emulsions applied using two different types excipients, i.e., poly(vinyl alcohol) (PVA) and glycyrrhizic acid (GA), address precipitation itraconazole (ITZ) as an amorphous solid. delivery profiles vitro dissolution tests ITZ–GA particles confirmed...

The flame retardancy of FPUFs can be enhanced by the manipulation solid-polymer interface chemistry.

Polymer crystallization obeys the laws of thermodynamics. Studying dynamic from melt to solid state may extend general understanding behavior polymers. In this work, non-isothermal kinetics copolyamide 6/12 (CoPA6/12) with different copolymerization ratios were investigated by differential scanning calorimetry. Jeziorny modified Avrami equation, Ozawa equation and Liu-Mo's method applied analyze CoPA6/12. The activation energy was evaluated using both Kissinger Friedman methods. Results show...

A new class of ultralight gold materials is produced by combining amyloid fibrils with nanoparticles, as described R. Mezzenga and co-workers on page 472. The content up to 20 karat equivalent allows the preservation optical properties traditional alloys, yet at densities thousands times lighter. By changing colloidal shape, size, concentration, composition material functionalities can be finely tuned, allowing catalysis pressure-sensing applications.